L-DOPA induces concentration-dependent facilitation and inhibition of presynaptic acetylcholine release in the guinea-pig submucous plexus

Brain Research

Volumn 718, Issue 1-2, 1996, Pages 105-111

  Hirai, Keiji ^a   Katayama, Yoshifumi ^a   Misu, Yoshimi ^b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Fast EPSP; Fura 2 microfluorophotometry; Intracellular calcium concentration; Intracellular recording; L DOPA; L DOPA methyl ester; Neurotransmitter release; Submucous plexus neuron

Indexed keywords

FURA 2; LEVODOPA;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CECUM; CONTROLLED STUDY; GUINEA PIG; INTRACELLULAR RECORDING; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029904224     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00061-3     Document Type: Article

References (23)

1. Akasu, T., Hirai, K. and Koketsu, K., Modulatory effect of ATP on the release of acetylcholine from presynaptic nerve terminals in bullfrog sympathetic ganglia, Kurume Med. J., 29 (1982) 75-83.
2. Battifora, H., Recent progress in the immunohistochemistry of solid tumors, Semin. Diagn. Pathol., 1 (1984) 251-271.
3. Bornstein, J.C., Lees, G.M. and McBain, C.J., Comparative effects of calcium antagonists on inhibitory junction potentials of circular muscle of guinea-pig ileum., Br. J. Pharmacol., 86 (1985) 724P.
4. del Castillo, J. and Katz, B., Quantal components of the end-plate potential, J. Physiol., 124 (1954) 560-573.
5. Goshima, Y., Nakamura, S. and Misu, Y., L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices, J. Pharmacol. Exp. Ther., 258 (1991) 466-471.
6. 2+-dependent and tetrodotoxin-sensitive release of endogenous glutamate from rat striatal slices, Brain Res., 617 (1993) 167-170.
7. 2+ indicators with greatly improved fluorescence properties, J. Biol. Chem., 260 (1985) 3440-3450.
8. Hirai, K. and Koketsu, K., Presynaptic regulation of the release of acetylcholine by 5-hydroxytryptamine, Br. J. Physiol., 77 (1980) 499-500.
9. Hirai, K. and Katayama, Y., Effect of the endogenous analgesic dipeptide, kyotorphin, on transmitter release in sympathetic ganglia, Br. J. Pharmacol., 85 (1985) 629-634.
10. Hirai, K. and Katayama, Y., Methionine enkephalin presynaptically facilitates and inhibits bullfrog sympathetic ganglionic transmission, Brain Res., 448 (1988) 299-307.
11. Koketsu, K., Akasu, T., Miyagawa, M. and Hirai, K., Modulation of nicotinic transmission by biogenic amines in bullfrog sympathetic ganglia, J. Auton. Nerv. Syst., 6 (1982) 47-53.
12. Kuba, K., Kato, E., Kumamoto, E., Koketsu, K. and Hirai, K., Sustained potentiation of transmitter release by adrenaline and dibutyryl cyclic AMP in sympathetic ganglionic transmission, Nature, 291 (1981) 654-656.
13. Martin, A.R., A further study of the statistical composition of the end-plate potential, J. Physiol., 130 (1955) 114-122.
14. Mihara, S., Intracellular recordings from neurones of the submucous plexus, Prog. Neurobiol., 40 (1993) 529-572.
15. Misu, Y. and Goshima, Y., Is L-dopa an endogenous neurotransmitter?, Trends Pharmacol. Sci., 14 (1993) 119-123.
16. Misu, Y., Ueda, H. and Goshima, Y., Neurotransmitter-like actions of L-DOPA, Adv. Pharmacol., 32 (1995) 427-459.
17. +-evoked release of 3,4-dihydroxyphenylalanine from the striatum in conscious rats studied by microdialysis, J. Neurochem., 58 (1992) 270-275.
18. Shen, Y.-L., Hirai, K. and Katayama, Y., Efects of TN-871 on synaptic transmission in bullfrog lumbar sympathetic ganglia, Jpn. J. Physiol., 42 (1992) S312.
19. Tatsumi, H., Hirai, K. and Katayama, Y., Measurement of the intracellular calcium concentration in guinea pig myenteric neurons by using fura-2, Brain Res., 451 (1988) 371-375.
20. Yue, J.L., Ueda, H. and Misu, Y., Evidence for a dopamine receptor subtype sensitive to combination of D1 with D2 antagonist in measurement of G-protein activity using rat striatal membranes, Life Sci., 54 (1994) PL413-418.
21. Yue, J.L., Nakamura, S., Ueda, H. and Misu, Y., Endogenously released L-dopa itself tonically functions to potentiate postsynaptic D2 receptor-mediated locomotor activities of conscious rats, Neurosci. Lett., 170 (1994) 107-110.
22. Zucker, R.S. and Lando, L., Mechanism of transmitter release: voltage hypothesis and calcium hypothesis, Science, 231 (1986) 574-579.
23. Zucker, R.S. and Haydon, P.G., Membrane potential has no direct role in evoking neurotransmitter release, Nature, 335 (1988) 360-362.