BPAg2 antibodies are present at lower levels than BPAg1 antibodies in serum from patients with bullous pemphigoid

European Journal of Dermatology

Volumn 6, Issue 7, 1996, Pages 491-494

  Ghohestani, Reza F ^a   Cozzani, Emanuel ^a   Kanitakis, Jean ^a   Nicolas, Jean François ^a   Faure, Michel ^a   Claudy, Alain L ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Autoantibodies; Autoimmune diseases; Hemidesmosomes; Serology

Indexed keywords

AUTOANTIBODY;

ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; PEMPHIGOID;

EID: 0029903968     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Bernard PH, Vaillant L, Labeille B, et al. Incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions. Arch Dermatol 1995; 131: 48-52.
2. Stanley JR. Autoantibodies against adhesion molecules and structures in blistering skin diseases. J Exp Med 1995; 181: 1-4.
3. Gaucherand M, Nicolas JF, Paranhos Baccala G, et al. Major antigenic epitopes of bullous pemphigoid 230 kDa antigen map within the C-terminal end of the protein; evidence using a 55 kDa recombinant protein. Br J Dermatol 1995; 132: 190-6.
4. Giudice GJ, Emery DJ, Zelickson BD, et al. Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BPAg180 ectodomain. J Immunol 1993; 151: 5742-50.
5. Kelly SE, Bhogal BS, Wojnarowska F, et al. Western blot analysis of the antigen in pemphigoid gestationis. Br J Dermatol 1990; 122: 445-9.
6. Ghohestani R, Nicolas JF, Kanitakis J, et al. Pemphigoid gestationis with autoantibodies exclusively directed against bullous pemphigoid 230 kDa antigen (BP230Ag). Br J Dermatol 1996; 134: 603-4.
7. Ghohestani R, Kanitakis J, Nicolas JF, et al. Comparative study of indirect immunofluoresence to immunoblot assay in detection of circulating antibodies to bullous pemphigoid antigen 1 and 2. Br J Dermatol 1996 (in press).
8. Reano A, Thivolet J, Staquet MJ, Fargier MC. Utilisation de la technique d'immunotransfert pour l'étude des anticorps présents dans le sérum de malades atteints de pemphigoïde bulleuse. Ann Dermatol Venereol 1988; 115: 11-8.
9. Machado P, Michalaki H, Roche P, et al. Serological diagnosis of bullous pemphigoid: comparison of the sensitivity of indirect immunofluorescence on salt-split skin to immunoblotting. Br J Dermatol 1992; 126: 236-41.
10. Peyron E, Nicolas JF, Reano A, et al. Human monoclonal auto-antibodies specific for the bullous pemphigoid antigen 1 (BPAg1). J Immunol 1994; 153: 1333-9.
11. Kelly SE, Wojnarowska F. Pemphigoid gestationis. Eur J Dermatol 1994; 4: 16-20.
12. Huilgol SC, Bhogal BS, Black MM. Immunofluorescence of the immunobullous disorders. Eur J Dermatol 1995; 5: 186-95.
13. Nicolas JF, Machado P, Cozzani E, Schmitt D. Techniques d'immunofluorescence appliquées au diagnostic des dermatoses bulleuses auto-immunes de la jonction dermo-épidermique. Ann Dermatol Venereol 1993; 120: 715-22.
14. Kitajima Y, Hirako Y, Owaribe K, Yaoita H. A possible cell-biologic mechanism involved in blister formation of bullous pemphigoid. Anti-180 kDa BP antibody is an initiator. Dermatology 1994; 189 (suppl 1): 46-59.
15. Liu Z, Diaz LA. Troy JL, et al. A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BPAg180. J Clin Invest 1993; 92: 2480-8.
16. Sams WM, Jordon RE. Correlation of pemphiaoid and pemphigus antibody titres with activity of disease. Br J Dermatol 1971; 84: 7-13.
17. Pas HH de Jong MCJM, Jonkman MF Heers K, Slijper-Pal IJ, Van der Meer JB. Bullous pemphigoid: serum antibody titre and antigen specificity. Exp Dermatol 1995; 4: 372-6.