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Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture
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A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet GPIIb/llIa complex
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The immunogenicity of the 7E3 murine monoelonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions
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Knight DM, Wagner C. Jordan R. MeAleer MF, DeRita R, Fass DN, Coller BS, Weisman HF, Ghrayeb J. The immunogenicity of the 7E3 murine monoelonal Fab antibody fragment variable region is dramatically reduced in humans by substitution of human for murine constant regions. Mol Immunol 1995;32:1271-1281.
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Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab Patients with Glanzmann thrombasthenia in Israel
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Coller BS, Cheresh DA. Asch E, Seiigsolm U. Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab Patients with Glanzmann thrombasthenia in Israel. Blood 1991;77:75-83.
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Monoclonal antibodies to platelet GPIIb/IIIa as antithrombotic agents
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Coller BS. Scudder LE, Beer J. Gold HK. Folts JD. Cabagnaro J. Jordan R, Wagner C, Iuliucci J. Knight D. Monoclonal antibodies to platelet GPIIb/IIIa as antithrombotic agents. Ann NY Acad Sci 1991:614:193-213.
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Inhibitors of the platelet glycoprotein Ilb/IIIa receptor as conjunctive therapy for coronary artery thrombolysis
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Coller BS. Inhibitors of the platelet glycoprotein Ilb/IIIa receptor as conjunctive therapy for coronary artery thrombolysis. Coron Art Dis 1992;3:1016-1029.
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Topol EJ, Calif! RM. Weismann HF, Ellis SG, Tcheng JE. Worley S. Ivanhoe R. George BS, Fintel D, Weston M. Randomized trial of coronary intervention with antibody against platelet Ilb/IIIa integrin for reduction of clinical restenosis: results at six months. Lancet 1994:343:881-886.
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0006421787
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Multicenter, randomized, double-blind pilot trial of standard versus low dose weight-adjusted heparin in patients treated with platelet GPIIb/IIIa receptor antibody c7E3 during percutaneous coronary revascularization
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Lincoff AM, Tcheng JE, Bass TA. Popma JJ, Teirstein PS, Kleiman NS, Weisman HF, Musco NH. Cabot CF. Berdan LGA. Multicenter, randomized, double-blind pilot trial of standard versus low dose weight-adjusted heparin in patients treated with platelet GPIIb/IIIa receptor antibody c7E3 during percutaneous coronary revascularization. JAm Coll Cardiol 1995;80A(Abstract)
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Effect of platelet glycoprotein Ilb/IIIa integrin blockade on activated clotting time during percutaneous transluminal coronary angioplasty or directional atherectomy (The EPIC trial). Evaluation of c7E3 Fab in the Prevention of Ischemic Complications trial
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Activated clotting lime of heparinized blood is increased by in vitro platelet glycoprotein Ilb/IIIa receptor blockade with antibody c7E3 Fab
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Ammar T. Sarier K. Coller BS. Activated clotting lime of heparinized blood is increased by in vitro platelet glycoprotein Ilb/IIIa receptor blockade with antibody c7E3 Fab. Thromb Haemostas 1995;73:1313(Abstract)
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Inhibition of platelet-mediated, tissue factor-induced, thrombin generation by the mouse/human chimeric 7E3 antibody: Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis"
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Reverter JC, Béguin S, Kessels H, Kumar R. Hemker HC, Coller BS. Inhibition of platelet-mediated, tissue factor-induced, thrombin generation by the mouse/human chimeric 7E3 antibody: potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis". J Clin Invest 1996;(in press)
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Wagner CL, Cunningham MR, Wyand MS, Weisman HF. Coller BS, Jordan RE. Reversal of the anti-platelet effects of chimeric 7E3 Fab treatment by platelet transfusion in cynomolgus monkeys. Thromb Haemostas 1995;73:1313(Abstract)
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A rapid, whole blood, bedside assay to monitor platelet glyco protein (GP) Ilb/IIIa blockade
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