Fluticasone propionate 1 mg daily and beclomethasone dipropionate 2 mg daily: A comparison over 1 yr

Respiratory Medicine

Volumn 90, Issue 10, 1996, Pages 609-617

  Lorentzen, K A ^a   Van Helmond, J L M ^b   Bauer, K ^c   Langaker, K E ^d   Bonifazi, F ^e   Harris, T A J ^f  

^a St Franciscus Ziekenhuis ^*  (Denmark)

^b SINT FRANCISCUS GASTHUIS   (Netherlands)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d Glaxo Research and Development Ltd ^*  (Norway)

^e Azienda Ospedaliera Umberto I   (Italy)

^f GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; FLUTICASONE PROPIONATE; GLUCOCORTICOID; HYDROCORTISONE;

ADULT; AGED; ARTICLE; ASTHMA; BRONCHITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; FEMALE; FORCED EXPIRATORY VOLUME; HEADACHE; HOARSENESS; HUMAN; HYDROCORTISONE BLOOD LEVEL; INHALATIONAL DRUG ADMINISTRATION; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINITIS; SORE THROAT; THRUSH; UROGENITAL TRACT DISEASE; VITAL CAPACITY;

EID: 0029902848     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0954-6111(96)90019-0     Document Type: Article

References (25)

1. Guidelines on the management of asthma. Thorax 1993; 48 (Suppl.): S1-S24.
2. International Consensus Report on Diagnosis and Management of Asthma. National Institute of Health. Publication No. 92-3091. Eur Resp J 1992; 5: 601-641.
3. Thompson NC. New therapy for asthma. Update 15 January 1994; 101-110.
4. Barnes PJ, Pedersen S. Efficacy and safety of inhaled corticosteroids in asthma. Am Rev Respir Dis 1993; 148: S1-26.
5. Boe J, Skoogh B-E. Is long-term treatment with inhaled steroids in adults hazardous? Eur Respir J 1992; 5: 1037-1039.
6. Geddes DM Inhaled corticosteriods: benefits and risks. Thorax 1992; 47: 404-407.
7. Brown PH, Blundell G, Greening AP et al. Hypothalamo-pituitary-adrenal axis suppression in asthmatics inhaling high dose corticosteroids. Respir Med 1991; 85: 501-510.
8. Barnes PJ. New drugs for asthma. Eur Respir J 1992; 5: 1126-1136.
9. Harding SM. The human pharmacology of fluticasone propionate. Respir Med 1990; 84 (Suppl. A): 25-29.
10. Dahl R, Lundback B, Malo J-L et al. A dose-ranging study of fluticasone propionate in adult patients with moderate asthma. Chest 1993; 104: 1352-1358.
11. Gustafsson P, Tsanakas J, Gold M, Primhak R, Radford M, Gillies E. A comparison of the efficacy and safety of inhaled fluticasone propionate 200 μg/day with inhaled beclomethasone dipropionate 400 μg/day in mild and moderate asthma. Arch Dis Child 1993; 69: 206-211.
12. Barnes NC, Marone G, Di Maria GU, Visser, Utama I, Payne SL. A comparison of fluticasone propionate 1 mg daily with beclomethasone dipropionate 2mg daily in the treatment of severe asthma. Eur Resp J 1993; 6: 877-884.
13. Leblanc P, Mink S, Keistinen T et al.. A comparison of fluticasone propionate 200 μg/day with beclomethasone dipropionate 400 μg/day in adult asthma. Allergy 1994; 49: 380-385.
14. Lundback B, Alexander M, Day J et al. Evaluation of fluticasone propionate (500 μg/day) administered either as dry powder via a Diskhaler inhaler or pressurised inhaler and compared with beclomethasone dipropionate (1000 μg/day) administered by pressurised inhaler. Respir Med 1993; 87: 609-620.
15. Langdon CG, Thompson J. A multicentre study to compare the efficacy and safety of inhaled fluticasone propionate and budesonide via metered dose inhalers with mild-to-moderate asthma. Br J Clin Res 1994; 5: 73-84.
16. Langdon CG, Capsey LJ. Fluticasone propionate and budesonide in adult asthmatics: a comparison using dry powder inhaler devices. Br J Clin Res 1994; 5: 85-99.
17. Connolly A. A comparison of fluticasone propionate 100 mg twice daily with budesonide 200 μg twice daily via their respective powder inhaler devices in the treatment of mild asthma. Eur J Clin Res 1995; 7: 15-29.
18. Ayres JG, Bateman ED, Lundback B, Harris TAJ. High dose fluticasone propionate, 1 mg daily, versus 2 mg daily, or budesonide, 1-6 mg daily, in patients with chronic severe asthma. Eur Respir J 1995; 8: 579-586.
19. Fabbri L, Burge PS, Croonenborgh L et al. Comparison of fluticasone propionate with beclomethasone dipropionate in moderate to severe asthma treated for one year. Thorax, 1993: 48: 817-823.
20. Bauer K, Bantje TA, Sips AP et al. The effects of inhaled fluticasone propionate (fluticasone propionate); a new potent corticosteroid in severe asthma. Eur Resp J 1988; 1 (Suppl 2): P201s.
21. Monson JP. Systemic effects of inhaled corticosteroids. Thorax 1993; 48: 955-956.
22. Brown PH, Blundell G, Greening AP et al. Screening for hypothalamic-pituitary-adrenal suppression in asthmatics taking high dose inhaled corticosteroids. Respir Med 1991; 85: 511-516.
23. Brown PH, Greening AP, Cromptin GK. Large volume spacer devices and the influence of high dose beclomethasone dipropionate on hypothalamic-pituitaryadrenal function. Thorax 1993; 48: 233-238.
24. Laursen LC, Taudorf E, Weeke B. High dose inhaled budesonide in treatment of severe steroid-dependent asthma. Eur J Respir Dis 1986; 68: 19-28.
25. Hägg E, Asplund K, Lithner F. Value of basal plasma cortisol assays in the assessment of pituitary-adrenal insufficiency. Clin Endocrinology 1987; 26: 221-226.