Differentiation and IFNγ regulate WAF1/CIP1 transcription in p53-independent and p53-dependent pathways in epithelial cells

In Vivo

Volumn 10, Issue 1, 1996, Pages 119-124

  Arany, Istvan ^a   Brysk, Miriam M ^a   Calhoun, Karen H ^a   Tyring, Stephen K ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Differentiation; Epithelia; Interferon; P53; WAF1 CIP1

Indexed keywords

GAMMA INTERFERON; PROTEIN P21; PROTEIN P53;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINIZATION; KERATINOCYTE; TRANSCRIPTION REGULATION;

EID: 0029902701     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Wille JJ, Pittelkow MR, Shipley GD and Scott RE: Integrated control of growth and differentiation of normal human prokeratinocytes cultured in serum-free medium: clonal analyses, growth kinetics, and cell cycle studies. J Cell Physiol 121: 31-44, 1984.
2. Fuchs E: Epidermal differentiation:the bare essentials. J Cell Biol 111: 2807-2814, 1990.
3. Saunders NA, Smith RJ and Jetten AM: Regulation of proliferation-specific and ' differentiation-specific genes during senescence of human epidermal keratinocyte and mammary epithelial cells. Biochem Biophys Res Commun 197: 46-54, 1993.
4. Saunders NA and Jetten AM: Control of growth regulatory and differentiation specific genes in human epidermal keratinocytes by interferon y. Antagonism by retinoic acid and transforming growth factor β1. J Biol Chem 269: 2016-2022, 1994.
5. Waga S, Hannon GJ, Beach D and Stillman B: The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369: 574-578, 1994.
6. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 75: 817-825, 1993.
7. Michieli P, Chedid M, Lin D, Pierce JH, Mercer WE and Givol D: Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res 54: 3391-3395, 1994.
8. Drysk MM, Arany I, Brysk H, Chen S-H, Calhoun KH and Tyring SK: Epithelial cell responsiveness to interferon gamma:epidermis vs. buccal mucosa. Mol Cell Differentiation 3: 213-223, 1995.
9. Brysk MM, Arany I, Brysk H, Chen S-H, Calhoun KH and Tyring SK: Gene expression of markers associated with proliferation and differentiation in keratinocytes cultured from skin and from oral mucosa. Arch Oral Biol, 40: 855-862, 1995.
10. Arany I, Rady P and Tyring SK: Interferon treatment enhances the expression of underphosphorylated (biologically active) retinoblastoma protein in human papillomavirus infected cells through the inhibitory TGFβ1 /IFNβ cytokine pathway. Antivir Res 23: 131-141,1994.
11. Fuchs E: Epidermal differentiation. Curr Opin Cell Biol 2: 1028-1035, 1990.
12. Steinman RA, Hoffman B, Iro A, Guillouf C, Liebermann DA and el-Houseini ME: Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 9: 3389-3396, 1994.
13. Johnson M, Dimitrov D, Vojta PJ, Barrett JC, Noda A, Pereira-Smith OM and Smith JR: Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/WAF1/p21 RNA in human cells. Mol Carcinog 11: 59-64, 1994.
14. Jiang H, Lin J, Su ZZ, Collart FR, Huberman E and Fisher PB: Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene 9: 3397-3406, 1994.
15. Hennings H, Michael D, Cheng C, Steinert P, Holbrook K and Yuspa SH: Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19: 245-254, 1980.
16. Luger TA and Schwarz T: Evidence for an epidermal cytokine network. J Invest Dermatol 95: 100s-104s, 1990.
17. Sheikh MS, Li XS, Chen JC, Shao ZM, Ordonez JV and Fontana JA: Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways. Oncogene 9: 3407-3415,1994.
18. Slebos RJC, Lee MH, Plunkett BS, Kessis TD, Williams BO, Jacks T, Hedrick L, Kastan MB and Cho KR: p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc Natl Acad Sci USA 91: 5320-5324, 1994.
19. Ozcdlik H, Mousses and Andrulis IL: Low levels of expression of an inhibitor of cyclin-dependent kinases (CIP1/WAF1) in primary breast carcinomas with p53 mutations. Clin Cancer Res 1: 907-912, 1995.
20. Jiang H, Lin J, Su Z, Herlyn M, Kerbel RS, Weissman BE, Welch DR and Fisher PB: The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells. Oncogene 10: 1855-1864, 1995.
21. Zhang W, Grasso L, McClain CD, Gambel AM, Cha Y, Travali S, Deisseroth AB and Mercer WE: p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation. Cancer Res 55: 668-674, 1995.
22. Reiss M, Vellucci VF and Zhou ZL: Mutant p53 tumor suppressor gene causes resistance to transforming growth factor β 1 in murine keratinocytes. Cancer Res 53: 899-904, 1993.