Retransplantation reverses mononuclear infiltration but not myointimal proliferation in a rat model of chronic cardiac allograft rejection

Transplantation

Volumn 61, Issue 12, 1996, Pages 1695-1699

  Schmid, Christof ^a   Heemann, Uwe ^b   Tilney, Nicholas L ^b  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD18 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RAPAMYCIN; SCLEROPROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ALLOGRAFT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HEART VENTRICLE FUNCTION; IMMUNOHISTOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

ANIMALS; CELL DIVISION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; GRAFT REJECTION; HEART TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; LEUKOCYTES, MONONUCLEAR; MALE; RATS; RATS, INBRED F344; RATS, INBRED LEW; REOPERATION; TRANSPLANTATION, HETEROTOPIC; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC; TUNICA INTIMA; VENTRICULAR FUNCTION;

EID: 0029902010     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199606270-00005     Document Type: Article

References (18)

1. Hosenpud JD, Novick RJ, Breen TJ, Daily PO. The registry of the International Society for Heart and Lung Transplantation: Eleventh Official Report-1994. J Heart Lung Transplant 1994; 13: 142.
2. Geerling RA, DeBruin RWF, Scheringa M, et al. Suppression of acute rejection prevents graft arteriosclerosis after allogenic aorta transplantation in the rat. Transplantation 1994; 58: 1258.
3. Schmid C, Heemann U, Azuma H, Tilney NL. Rapamycin inhibits transplant vasculopathy in long-surviving rat heart allografts. Transplantation 1995; 60: L729.
4. Tilney NL, Whitely WD, Diamond JR, Kupiec-Weglinski JW, Adams DH. Chronic rejection - an undefined conundrum. Transplantation 1991; 52: 389.
5. Tullius SG, Tilney NL. Both alloantigen-dependent and -independent factors influence chronic allograft rejection. Transplantation 1995; 59: 313.
6. Schmid C, Heemann U, Azuma H, Tilney NL. Transplant vasculopathy in rat heart transplantation - a morphologic chameleon determined by antigen-dependent and independent factors. Transplant Proc 1995; 27: 2077.
7. Meiser B, Billingham ME, Morris RE. Effects of cyclosporin, FK 506, and rapamycin in graft-vessel disease. Lancet 1991; 338: 1297.
8. Kupiec-Weglinski JW, Araujo JL, Towpik E, et al. Host-graft relationship: the systemic nature of allograft rejection. Surgery 1985; 98: 259.
9. Schmid C, Binder J, Heemann U, Tilney NL. Successful heterotopic heart transplantation in the rat. Microsurgery 1994; 15: 279.
10. Harlow E, Lane D. Antibodies. A laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory, 1988: 359.
11. Schoen FJ, Libby P. Cardiac transplant graft arteriosclerosis. Trends Cardiovasc Med 1991; 1: 216.
12. Yilmaz S, Paavonen T, Häyry P. Chronic rejection of rat renal allografts. II. The impact of prolonged ischemia time on transplant vasculopathy. Transplantation 1992; 53: 823.
13. Gohra H, McDonald TO, Verrier ED, Aziz S. Endothelial loss and regeneration in a model of transplant arteriosclerosis. Transplantation 1995; 60: 96.
14. Masetti P, DiSiesa VJ, Schoen FJ, et al. Ischemic injury before heart transplantation does not cause coronary arteriopathy in experimental isografts. J Heart Lung Transplant 1991; 10: 597.
15. Tullius SG, Heemann UW, Wagner K, Tilney NL. Changes of chronic kidney allograft rejection are reversible after retransplantation. Transplant Proc 1993; 25: 906.
16. Hanna AK, DiSesa VJ. Reversal of cardiac allograft rejection without immunotherapy: an animal model. Ann Thorac Surg 1993; 56: 1335.
17. Shirotani M, Yui Y, Kawai C. Restenosis after coronary angioplasty: pathogenesis of neointimal thickening initiated by endothelial loss. Endothelium 1993; 1: 5.
18. Shackleton CR, Ettinger SL, McLoughlin MG, Scudamore CH, Miller RR, Keown PA. Effect of recovery from ischemic injury on class I and class II MHC antigen expression. Transplantation 1990; 49: 641.