CD4+ T cell mediated destruction of xenografts within cell-impermeable membranes in the absence of CD8+ T cells and B cells

Transplantation

Volumn 61, Issue 12, 1996, Pages 1678-1684

  Loudovaris, Thomas ^a,b   Mandel, Thomas E ^a   Charlton, Brett ^a,c  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b BAXTER HEALTHCARE CORPORATION   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD4 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL CELL; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CERCOPITHECIDAE; CONTROLLED STUDY; DIFFUSION CHAMBER; FEMALE; FLOW CYTOMETRY; GRAFT SURVIVAL; MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE; XENOGRAFT;

ANIMALS; ANTIBODIES; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL MEMBRANE PERMEABILITY; CELL TRANSPLANTATION; CERCOPITHECUS AETHIOPS; FEMALE; GRAFT REJECTION; KIDNEY; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; MICE, NUDE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0029901796     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199606270-00003     Document Type: Article

References (36)

1. Sachs DH, Bach FH. Immunology of xenograft rejection. Hum Immunol 1990; 28: 245.
2. Calne RY. Organ transplantation between widely disparate species. Transplant Proc 1970; 2: 550.
3. Hammer C, Chaussy C, Brendel W. Preformed natural antibodies in animals and man. Outlook on xenotransplantation. Eur Surg Res 1973; 5: 162.
4. Geller RL, Turman MA, Dalmasso AP, Platt JL. The natural immune barrier to xenotransplantation. J Am Soc Nephrol 1992; 3: 1189.
5. + helper T cells and self antigen-presenting cells in the mouse. J Exp Med 1990; 172: 567.
6. Moses RD, Auchincloss H Jr. Defects in accessory molecule and other cell surface molecule interactions are responsible for weak mouse helper T-cell responses to xenoantigens. Transplant Proc 1991; 23: 883.
7. Moses RD, Winn HJ, Auchincloss H Jr. Evidence that multiple defects in cell-surface molecule interactions across species differences are responsible for diminished xenogeneic T cell responses. Transplantation 1992; 53: 203.
8. Algire GH, Weaver JM, Prehn RT. Growth of cells in vivo in diffusion chambers. I. Survival of homografts in immunized mice. J Natl Cancer Inst 1954; 15: 493.
9. Prehn RT, Weaver JM, Algire GH. The diffusion-chamber technique applied to a study of the nature of homograft resistance. J Natl Cancer Inst 1954; 15: 509.
10. Weaver JM, Algire GH, Prehn RT. Growth of cells in vivo in diffusion chambers. II. The role of cells in the destruction of homografts in mice. J Natl Cancer Inst 1955; 15: 1737.
11. Amos DB. The use of simplified systems as an aid to the interpretation of mechanisms of graft rejection. Prog Allergy 1962; 6: 468.
12. Brauker J, Martinson LA, Loudovaris T, et al. Immunisolation with large pore membranes: allografts are protected under conditions that result in destruction of xenografts. Cell Transplant 1992; 1: 164.
13. Loudovaris T, Charlton B, Hodgson RJ, Mandel TE. Destruction of xenografts but not allografts within cell impermeable membranes. Transplant Proc 1992; 24: 2291.
14. Ledbetter JA, Herzenberg LA. Xenogeneic monoclonal antibodies to lymphoid differentiation antigens. Immunol Rev 1979; 47: 63.
15. Dialynas DP, Quan ZS, Wall KA, et al. Characterization of the murine T cell surface molecule designated L3T4 identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule. J Immunol 1983; 131: 2445.
16. Algire GH. Diffusion-chamber techniques for studies of cellular immunity. Ann NY Acad Sci 1957; 69: 663.
17. Brauker J, Martinson LA, Young SK, Johnson RC. Local inflammatory response around diffusion chambers containing xenografts: non-specific destruction of tissues and decreased local vascularization. Transplantation 1996; 61: 1671.
18. Mueller BM, Romerdahl CA, Trent JM, Reisfeld RA. Suppression of spontaneous melanoma metastasis in SCID mice with an antibody to the epidermal growth factor receptor. Cancer Res 1991; 51: 2193.
19. Roder J, Duwe A. The beige mutation in the mouse selectively impairs natural killer cells. Nature 1979; 278: 451.
20. Ghobrial RR, Boublik M, Winn HJ, Auchincloss H Jr. In vivo use of monoclonal antibodies against murine T cell antigens. Clin Immunol Immunopathol 1989; 52: 486.
21. Flavin T, Shizuru J, Seydel K, et al. Selective T-cell depletion with Ox-38 anti-CD4 monoclonal antibody prevents cardiac allograft rejection in rats. J Heart Transplant 1990; 9: 482.
22. + cells in rejection of multiple minor H-disparate skin grafts. Transplantation 1989; 47: 909.
23. + cells in islet allo- and xeno-graft rejection. Horm Metab Res 1990; Suppl. 25: 173.
24. + cells in islet allograft rejection. Transplantation 1990; 50: 120.
25. + T cell-depleted mice by xenotransplantation of pig proislets. Transplant Proc 1989; 49: 849.
26. Kaufman DS, Kong CS, Shizuru JA, Gregory AK, Fathman CG. Use of anti-L3T4 and anti-Ia treatments for prolongation of xenogeneic islet transplants. Transplantation 1988; 46: 210.
27. + T cell-depleted diabetic mice. Transplantation 1990; 50: 657.
28. + T lymphocyte-deficient mice. Transplantation 1993; 55: 718.
29. + T-lymphocytes. Transplant Proc 1992; 24: 2877.
30. Chen Z, Cobbold S, Metcalfe S, Waldmann H. Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts and to rat heart xenografts using monoclonal antibodies to CD4 and CD8. Eur J Immunol 1992; 22: 805.
31. Bosma GC, Custer RP, Bosman MJ. A severe combined immunodeficiency mutation in the mouse. Nature 1983; 301: 527.
32. + or B lymphocytes can reject xenogeneic skin grafts. Xenotransplantation 1994; 1: 8.
33. + T cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract. J Exp Med 1992; 175: 1685.
34. + cells in the resistance to Pneumocystis carinii pneumonia in mice. J Exp Med 1990; 172: 937.
35. + helper T cells in the destruction of microencapsulated islet xenografts in nod mice. Transplantation 1990; 49: 396.
36. Weber CJ, Ayres-Price J, Costanzo M, Baker A, Stall A. NOD mouse peritoneal cellular response to poly-L-lysine-alginate microencapsulated rat islets. Transplant Proc 1994; 26: 1116.