메뉴 건너뛰기




Volumn 42, Issue 1, 1996, Pages 43-52

Transgenic mouse models in carcinogenesis: Interaction of c-myc with transforming growth factor a and hepatocyte growth factor in hepatocarcinogenesis

Author keywords

Carcinogenesis; Oncogenes; Suppressor genes; Transgenic mouse

Indexed keywords

PHENOBARBITAL; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0029901652     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1996.03748.x     Document Type: Conference Paper
Times cited : (40)

References (84)
  • 1
    • 0023145547 scopus 로고
    • The molecular genetics of cancer
    • Bishop JM. The molecular genetics of cancer. Science 1987; 235: 305-308.
    • (1987) Science , vol.235 , pp. 305-308
    • Bishop, J.M.1
  • 2
    • 0026010995 scopus 로고
    • Molecular themes in ontogenesis
    • Bishop JM. Molecular themes in ontogenesis. Cell 1991; 64: 235-248.
    • (1991) Cell , vol.64 , pp. 235-248
    • Bishop, J.M.1
  • 3
    • 0026074818 scopus 로고
    • Cooperation between oncogenes
    • Hunter T. Cooperation between oncogenes. Cell 1991; 64: 249-270.
    • (1991) Cell , vol.64 , pp. 249-270
    • Hunter, T.1
  • 4
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon EF, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.F.1    Vogelstein, B.2
  • 6
    • 0024155366 scopus 로고
    • Dissecting multistep tumorigenesis in transgenic mice
    • Hanahan D. Dissecting multistep tumorigenesis in transgenic mice. Ann Rev Genet 1988; 22: 479-519.
    • (1988) Ann Rev Genet , vol.22 , pp. 479-519
    • Hanahan, D.1
  • 7
    • 0025953899 scopus 로고
    • Myc family oncogenes in development of normal and neoplastic cells
    • DePinho RA, Schreiber-Agus N, Alt FW. Myc family oncogenes in development of normal and neoplastic cells. Adv Cancer Res 1991; 57: 1-46.
    • (1991) Adv Cancer Res , vol.57 , pp. 1-46
    • DePinho, R.A.1    Schreiber-Agus, N.2    Alt, F.W.3
  • 8
    • 0025607921 scopus 로고
    • New light on myc and myb. Part. I. Myc
    • Luscher B, Eisenman RN. New light on myc and myb. Part. I. Myc. Genes Dev 1990; 4: 2025-2035.
    • (1990) Genes Dev , vol.4 , pp. 2025-2035
    • Luscher, B.1    Eisenman, R.N.2
  • 9
    • 0345257594 scopus 로고
    • Use of transgenic mice to study normal and abnormal mammalian development
    • eds Broder S, et al., Baltimore, MD: Williams and Wilkins
    • Moroy T, Alt FW, DePinho RA. Use of transgenic mice to study normal and abnormal mammalian development. In Molecular Foundation of Oncology, eds Broder S, et al., Baltimore, MD: Williams and Wilkins, 1991: 455-487.
    • (1991) Molecular Foundation of Oncology , pp. 455-487
    • Moroy, T.1    Alt, F.W.2    DePinho, R.A.3
  • 10
    • 0010452104 scopus 로고
    • c-Myc gene amplification during hepatocarcinogenesis by a choline-devoid diet
    • Chandar N, Lombardi B, Locker J. c-Myc gene amplification during hepatocarcinogenesis by a choline-devoid diet. Proc. Natl Acad Sci USA, 1989; 86: 2703-2707.
    • (1989) Proc. Natl Acad Sci USA , vol.86 , pp. 2703-2707
    • Chandar, N.1    Lombardi, B.2    Locker, J.3
  • 11
    • 0021912710 scopus 로고
    • Expression of c-Ki-ras, c-Ha-ras and c-myc in specific cell types during hepatocarcinogenesis
    • Yaswen P, Goyette M, Shank PR, Fausto N. Expression of c-Ki-ras, c-Ha-ras and c-myc in specific cell types during hepatocarcinogenesis. Mol Cell Biol 1985; 5: 780-786.
    • (1985) Mol Cell Biol , vol.5 , pp. 780-786
    • Yaswen, P.1    Goyette, M.2    Shank, P.R.3    Fausto, N.4
  • 13
    • 0023767641 scopus 로고
    • Cellular distribution of c-myc transcripts during chemical hepatocarcinogenesis in rats
    • Nagy P, Evarts RP, Marsden E, Roach J. Thorgeirsson SS. Cellular distribution of c-myc transcripts during chemical hepatocarcinogenesis in rats. Cancer Res 1988; 48: 5522-5527.
    • (1988) Cancer Res , vol.48 , pp. 5522-5527
    • Nagy, P.1    Evarts, R.P.2    Marsden, E.3    Roach, J.4    Thorgeirsson, S.S.5
  • 14
    • 0023100052 scopus 로고
    • Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumours
    • Derynck R, Goeddel DV, Ullrich A. et al. Synthesis of messenger RNAs for transforming growth factors α and β and the epidermal growth factor receptor by human tumours. Cancer Res 1987; 47: 707-712.
    • (1987) Cancer Res , vol.47 , pp. 707-712
    • Derynck, R.1    Goeddel, D.V.2    Ullrich, A.3
  • 15
    • 0023949586 scopus 로고
    • Transforming growth factors produced by normal and neoplastically transformed rat liver epithelial cells in culture
    • Liu C, Tsao MS, Grisham JW. Transforming growth factors produced by normal and neoplastically transformed rat liver epithelial cells in culture. Cancer Res 1988; 48: 850-855.
    • (1988) Cancer Res , vol.48 , pp. 850-855
    • Liu, C.1    Tsao, M.S.2    Grisham, J.W.3
  • 16
    • 0024327902 scopus 로고
    • Regulation of transforming growth factor α messenger RNA expression in a chemically transformed rat hepatic epithelial cell line by phorbol ester and hormones
    • Raymond VW, Lee DC, Grisham JW, Earp HS. Regulation of transforming growth factor α messenger RNA expression in a chemically transformed rat hepatic epithelial cell line by phorbol ester and hormones. Cancer Res 1989; 49: 3608-3612.
    • (1989) Cancer Res , vol.49 , pp. 3608-3612
    • Raymond, V.W.1    Lee, D.C.2    Grisham, J.W.3    Earp, H.S.4
  • 17
    • 0020806079 scopus 로고
    • Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: Amino acid sequence homology with epidermal growth factor
    • Marquardt H, Hunkapillar MW, Hood LE, et al. Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor. Proc Natl Acad Sci USA 1983; 80: 4684-4688.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4684-4688
    • Marquardt, H.1    Hunkapillar, M.W.2    Hood, L.E.3
  • 18
    • 0021013896 scopus 로고
    • Epidermal growth factor-like transforming growth factor II. Interaction with epidermal growth factor receptors on human placenta membrane and A431 cells
    • Massague J. Epidermal growth factor-like transforming growth factor II. Interaction with epidermal growth factor receptors on human placenta membrane and A431 cells. J Biol Chem 1983; 258: 13614-13620.
    • (1983) J Biol Chem , vol.258 , pp. 13614-13620
    • Massague, J.1
  • 19
    • 0021360015 scopus 로고
    • Rat transforming growth factor type I: Structure and relation to epidermal growth factor
    • Marquardt H, Hunkapillar MW, Hood LE, Todaro GJ. Rat transforming growth factor type I: structure and relation to epidermal growth factor. Science 1984; 223: 1079-1082.
    • (1984) Science , vol.223 , pp. 1079-1082
    • Marquardt, H.1    Hunkapillar, M.W.2    Hood, L.E.3    Todaro, G.J.4
  • 21
    • 0025777146 scopus 로고
    • Characterization of trans-immortalized hepatic cell lines established from transgenic mice
    • Perraud F, Dalemans W, Genrault JL, et al. Characterization of trans-immortalized hepatic cell lines established from transgenic mice. Exp Cell Res 1991; 195: 59-65.
    • (1991) Exp Cell Res , vol.195 , pp. 59-65
    • Perraud, F.1    Dalemans, W.2    Genrault, J.L.3
  • 22
    • 0025341727 scopus 로고
    • TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
    • Jhappan C, Stahle C, Harkins RN, Fausto N, Smith GH, Merlino GT. TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell 1990; 61: 1137-1146.
    • (1990) Cell , vol.61 , pp. 1137-1146
    • Jhappan, C.1    Stahle, C.2    Harkins, R.N.3    Fausto, N.4    Smith, G.H.5    Merlino, G.T.6
  • 23
    • 0025297086 scopus 로고
    • Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGFα in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990; 61: 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 24
    • 0026656358 scopus 로고
    • Hypertrophic gastropathy resembling Menetrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach
    • Takagi H, Jhappan C, Sharp R, Merlino G. Hypertrophic gastropathy resembling Menetrier's disease in transgenic mice overexpressing transforming growth factor alpha in the stomach. J Clin Invest 1991; 90: 1161-1167.
    • (1991) J Clin Invest , vol.90 , pp. 1161-1167
    • Takagi, H.1    Jhappan, C.2    Sharp, R.3    Merlino, G.4
  • 26
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura T, Nawa K, Ichiara A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 1984; 122: 1450-1459.
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichiara, A.3
  • 27
    • 0026048814 scopus 로고
    • Localization of hepatocyte growth factor in human and rat tissues: An immunohistochemical study
    • Wolf HK, Zarnegar R, Michalopoulos GK. Localization of hepatocyte growth factor in human and rat tissues: an immunohistochemical study. Hepatology 1991; 14: 488-494.
    • (1991) Hepatology , vol.14 , pp. 488-494
    • Wolf, H.K.1    Zarnegar, R.2    Michalopoulos, G.K.3
  • 28
    • 0027744494 scopus 로고
    • Expression of hepatocyte growth factor and c-met genes during hepatic differentiation and liver development in the rat
    • Hu Z, Evarts RP, Fujio K, Marsden ER, Thorgeirsson SS. Expression of hepatocyte growth factor and c-met genes during hepatic differentiation and liver development in the rat. Am J Pathol 1993; 142: 1823-1830.
    • (1993) Am J Pathol , vol.142 , pp. 1823-1830
    • Hu, Z.1    Evarts, R.P.2    Fujio, K.3    Marsden, E.R.4    Thorgeirsson, S.S.5
  • 29
    • 0028207168 scopus 로고
    • Ultrastructural location of human hepatocyte growth factor in human liver
    • Sakaguchi H, Seki S, Tsubouchi H, et al. Ultrastructural location of human hepatocyte growth factor in human liver. Hepatology 1994; 19: 1157-1163.
    • (1994) Hepatology , vol.19 , pp. 1157-1163
    • Sakaguchi, H.1    Seki, S.2    Tsubouchi, H.3
  • 30
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M, Gherardi E, Perryman M, Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987; 327: 239-242.
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 31
    • 0025886454 scopus 로고
    • Evidence for the identity of human scatter factor and human hepatocyte growth factor
    • Weidner KM, Arakaki N, Hartmann G, et al. Evidence for the identity of human scatter factor and human hepatocyte growth factor. Proc Natl Acad Sci USA 1991; 88: 7001-7005.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7001-7005
    • Weidner, K.M.1    Arakaki, N.2    Hartmann, G.3
  • 32
    • 0025771101 scopus 로고
    • Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor
    • Naldini L, Weidner KM, Vigna E, et al. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 1991; 10: 2867-2878.
    • (1991) EMBO J , vol.10 , pp. 2867-2878
    • Naldini, L.1    Weidner, K.M.2    Vigna, E.3
  • 33
    • 0025855880 scopus 로고
    • Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes
    • Strain A, Ismail T, Tsubouchi H, et al. Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes. J Clin Invest 1991; 87: 1853-1857.
    • (1991) J Clin Invest , vol.87 , pp. 1853-1857
    • Strain, A.1    Ismail, T.2    Tsubouchi, H.3
  • 34
    • 0027344558 scopus 로고
    • Roles of HGF as a pleiotropic factor in organ regeneration
    • eds. Goldberg ID, Rosen EM. Birkhäuser: Verlag, Basel
    • Matsumoto K, Nakamura T. Roles of HGF as a pleiotropic factor in organ regeneration. In Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-Met Receptor. eds. Goldberg ID, Rosen EM. Birkhäuser: Verlag, Basel, 1993: 225-249.
    • (1993) Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-Met Receptor , pp. 225-249
    • Matsumoto, K.1    Nakamura, T.2
  • 35
    • 0026722243 scopus 로고
    • Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
    • Bussolino F, Di Renzo MF, Ziche M, et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 1992; 119: 629-641.
    • (1992) J Cell Biol , vol.119 , pp. 629-641
    • Bussolino, F.1    Di Renzo, M.F.2    Ziche, M.3
  • 37
    • 0028999868 scopus 로고
    • The many faces of hepatocyte growth factor: From hepatopoiesis to hematopoiesis
    • Zarnegar R, Michalopoulos GK. The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J Cell Biol 1995; 129: 1177-1180.
    • (1995) J Cell Biol , vol.129 , pp. 1177-1180
    • Zarnegar, R.1    Michalopoulos, G.K.2
  • 38
    • 0026669204 scopus 로고
    • Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine epithelial cells
    • Pepper MS, Matsumoto K, Nakamura T, Orci L, Montesano R. Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine epithelial cells. J Biol Chem 1992; 267: 20493.
    • (1992) J Biol Chem , vol.267 , pp. 20493
    • Pepper, M.S.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4    Montesano, R.5
  • 39
    • 0028337426 scopus 로고
    • Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in HepG2 cells
    • Wojta J, Nakamura T, Fabry A. et al. Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in HepG2 cells. Blood 1994; 84: 151-157.
    • (1994) Blood , vol.84 , pp. 151-157
    • Wojta, J.1    Nakamura, T.2    Fabry, A.3
  • 41
    • 0028605945 scopus 로고
    • The expression of regenerative growth factors in chronic liver injury and repair
    • Aldana PR, Goerke ME, Carr SC, Tracy TF Jr. The expression of regenerative growth factors in chronic liver injury and repair. J Surg Res 1994; 57: 711-717.
    • (1994) J Surg Res , vol.57 , pp. 711-717
    • Aldana, P.R.1    Goerke, M.E.2    Carr, S.C.3    Tracy Jr., T.F.4
  • 42
    • 0028564863 scopus 로고
    • Scatter Factor and the c-Met receptor: A paradigm for mesenchymal/epithelial interaction
    • Rosen EM, Nigam SK, Goldberg ID. Scatter Factor and the c-Met receptor: a paradigm for mesenchymal/epithelial interaction. J Cell Biol 1994; 127: 1783-1787.
    • (1994) J Cell Biol , vol.127 , pp. 1783-1787
    • Rosen, E.M.1    Nigam, S.K.2    Goldberg, I.D.3
  • 43
    • 0028899952 scopus 로고
    • Scatter factor hepatocyte growth factor is essential for liver development
    • Schmidt C, Bladt F, Goedecke S, et al. Scatter factor hepatocyte growth factor is essential for liver development. Nature 1995; 373: 699-702.
    • (1995) Nature , vol.373 , pp. 699-702
    • Schmidt, C.1    Bladt, F.2    Goedecke, S.3
  • 44
    • 0028911690 scopus 로고
    • Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
    • Uehara Y, Uehara Y, Minowa O, et al. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 1995; 373: 702-705.
    • (1995) Nature , vol.373 , pp. 702-705
    • Uehara, Y.1    Uehara, Y.2    Minowa, O.3
  • 45
    • 0025805633 scopus 로고
    • Identification of the HGF receptor as the c-Met proto-oncogene product
    • Bottaro DP, Rubin JS, Faletto DL, et al. Identification of the HGF receptor as the c-Met proto-oncogene product. Science 1991; 251: 802-804.
    • (1991) Science , vol.251 , pp. 802-804
    • Bottaro, D.P.1    Rubin, J.S.2    Faletto, D.L.3
  • 46
    • 0027348905 scopus 로고
    • Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cells
    • eds Goldberg ID, Rosen EM. Birkhäuser Verlag, Basel
    • Comoglio PM. Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cells. In Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-Met receptor, eds Goldberg ID, Rosen EM. Birkhäuser Verlag, Basel. 1993: 131-165.
    • (1993) Hepatocyte Growth Factor-Scatter Factor (HGF-SF) and c-Met Receptor , pp. 131-165
    • Comoglio, P.M.1
  • 47
    • 0027410889 scopus 로고
    • The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells
    • Weidner KM, Sachs M, Birchmeier W. The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells. J Cell Biol 1993; 127: 145-154.
    • (1993) J Cell Biol , vol.127 , pp. 145-154
    • Weidner, K.M.1    Sachs, M.2    Birchmeier, W.3
  • 48
    • 0025954574 scopus 로고
    • The receptor encoded by the human c-met oncogene is expressed in hepatocytes, epithelial cells and solid tumors
    • Prat M, Narsimhan RP, Crepaldi T, et al. The receptor encoded by the human c-met oncogene is expressed in hepatocytes, epithelial cells and solid tumors. Int J Cancer 1991; 49: 323-328.
    • (1991) Int J Cancer , vol.49 , pp. 323-328
    • Prat, M.1    Narsimhan, R.P.2    Crepaldi, T.3
  • 49
    • 0026655776 scopus 로고
    • Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
    • Rong S, Bodescot M, Blair D, et al. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol 1992; 12: 5152-5158.
    • (1992) Mol Cell Biol , vol.12 , pp. 5152-5158
    • Rong, S.1    Bodescot, M.2    Blair, D.3
  • 50
    • 0026441272 scopus 로고
    • Overexpression of the c-met/HGF receptor gene in human thyroid carcinomas
    • Di Renzo MF, Olivero M, Ferro S, et al. Overexpression of the c-met/HGF receptor gene in human thyroid carcinomas. Oncogene 1992; 7: 2549-2553.
    • (1992) Oncogene , vol.7 , pp. 2549-2553
    • Di Renzo, M.F.1    Olivero, M.2    Ferro, S.3
  • 52
    • 0027633237 scopus 로고
    • Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells
    • Tsao MS, Zhu H, Giaid A, et al. Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. Cell Growth Differ 1993; 4: 571-579.
    • (1993) Cell Growth Differ , vol.4 , pp. 571-579
    • Tsao, M.S.1    Zhu, H.2    Giaid, A.3
  • 53
    • 0027939437 scopus 로고
    • Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer
    • Ebert M, Yokoyama M, Friess H, Büchler MW, Korc M. Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer. Cancer Res 1994; 54: 5775-5778.
    • (1994) Cancer Res , vol.54 , pp. 5775-5778
    • Ebert, M.1    Yokoyama, M.2    Friess, H.3    Büchler, M.W.4    Korc, M.5
  • 54
    • 0027382172 scopus 로고
    • Expression of the c-met/HGF receptor in human melanocytic neoplasms: Demonstration of the relationship to malignant melanoma tumour progression
    • Natala PG, Nicotra MR, Di Renzo MF, et al. Expression of the c-met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression. Br J Cancer 1993; 68: 746-750.
    • (1993) Br J Cancer , vol.68 , pp. 746-750
    • Natala, P.G.1    Nicotra, M.R.2    Di Renzo, M.F.3
  • 55
    • 0028268338 scopus 로고
    • Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increase tumorigenicity
    • Bellusci S, Moens G, Gaudino G, et al. Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increase tumorigenicity. Oncogene 1994; 9: 1091-1099.
    • (1994) Oncogene , vol.9 , pp. 1091-1099
    • Bellusci, S.1    Moens, G.2    Gaudino, G.3
  • 56
    • 0028276786 scopus 로고
    • Invasiveness and metastasis of NIH/3T3 cells induced by Met-HGF/SF autocrine stimulation
    • Rong S, Segal S, Anver M, Resau JH, Vande Woude GF. Invasiveness and metastasis of NIH/3T3 cells induced by Met-HGF/SF autocrine stimulation. Proc Natl Acad Sci USA 1994; 91: 4731-4735.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4731-4735
    • Rong, S.1    Segal, S.2    Anver, M.3    Resau, J.H.4    Vande Woude, G.F.5
  • 57
    • 0028946604 scopus 로고
    • Overexpression and amplilication of the met/HGF receptor gene during progression of colorectal cancer
    • Di Renzo MF, Olivero M, Giacomini A, et al. Overexpression and amplilication of the met/HGF receptor gene during progression of colorectal cancer. Clin Cancer Res 1995; 1: 147-154.
    • (1995) Clin Cancer Res , vol.1 , pp. 147-154
    • Di Renzo, M.F.1    Olivero, M.2    Giacomini, A.3
  • 58
    • 0028937152 scopus 로고
    • Met protooncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients
    • Rong S, Donehower LA, Hansen MF, et al. Met protooncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients. Cancer Res 1995; 55: 1963-1970.
    • (1995) Cancer Res , vol.55 , pp. 1963-1970
    • Rong, S.1    Donehower, L.A.2    Hansen, M.F.3
  • 59
    • 0025171006 scopus 로고
    • Identity of a tumor cytotoxic factor from human fibroblasts and hepatocyte growth factor
    • Higashio K, Shima N, Goto M, et al. Identity of a tumor cytotoxic factor from human fibroblasts and hepatocyte growth factor. Biochem Biophys Res Commun 1990; 170: 397-404.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 397-404
    • Higashio, K.1    Shima, N.2    Goto, M.3
  • 60
    • 0026046210 scopus 로고
    • Hepatocyte growth factor has a potent anti-proliferalive activity in various tumor cell lines
    • Tajima H, Matsumoto K, Nakamura T. Hepatocyte growth factor has a potent anti-proliferalive activity in various tumor cell lines. FEBS Lett 1991; 291: 229-232.
    • (1991) FEBS Lett , vol.291 , pp. 229-232
    • Tajima, H.1    Matsumoto, K.2    Nakamura, T.3
  • 61
    • 0025787867 scopus 로고
    • Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein
    • Shima N, Nagao M, Ogaki F, et al. Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: cloning of its cDNA, purification and characterization of recombinant protein. Biochem Biophys Res Commun 1991; 180: 1151-1158.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 1151-1158
    • Shima, N.1    Nagao, M.2    Ogaki, F.3
  • 63
    • 0028137180 scopus 로고
    • Inhibitory effect of hepatocyte growth factor against FaO hepatocellular carcinoma cells may be associated with changes of intracellular signaling pathways mediated by protein kinase C
    • Shiota G, Kawasaki H, Nakamura T, Schmidt EV. Inhibitory effect of hepatocyte growth factor against FaO hepatocellular carcinoma cells may be associated with changes of intracellular signaling pathways mediated by protein kinase C. Res Commun Mol Pathol Pharmacol 1994; 85: 271-278.
    • (1994) Res Commun Mol Pathol Pharmacol , vol.85 , pp. 271-278
    • Shiota, G.1    Kawasaki, H.2    Nakamura, T.3    Schmidt, E.V.4
  • 64
    • 0028965029 scopus 로고
    • Hepatocyte growth factor inhibits cell proliferation in vivo of rat hepatocellular carcinomas induced by diethylnitrosamine
    • Liu ML, Mars WM, Michalopoulos GK. Hepatocyte growth factor inhibits cell proliferation in vivo of rat hepatocellular carcinomas induced by diethylnitrosamine. Cardinogenesis 1995; 16: 841-843.
    • (1995) Cardinogenesis , vol.16 , pp. 841-843
    • Liu, M.L.1    Mars, W.M.2    Michalopoulos, G.K.3
  • 65
    • 0028587320 scopus 로고
    • The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergize with epidermal growth factor to promote clonal expansion of initiated rat hepatocytes
    • James NH, Roberts RA. The peroxisome proliferator class of non-genotoxic hepatocarcinogens synergize with epidermal growth factor to promote clonal expansion of initiated rat hepatocytes. Carcinogenesis 1994; 15: 2687-2694.
    • (1994) Carcinogenesis , vol.15 , pp. 2687-2694
    • James, N.H.1    Roberts, R.A.2
  • 66
    • 0028213841 scopus 로고
    • Hepatocyte growth factor in transgenic mice: Effects on hepatocyte growth, liver regeneration and gene expression
    • Shiota G, Wang TC, Nakamura T, Schmidt EV. Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression. Hepatology 1994; 19: 962.
    • (1994) Hepatology , vol.19 , pp. 962
    • Shiota, G.1    Wang, T.C.2    Nakamura, T.3    Schmidt, E.V.4
  • 67
    • 0027245446 scopus 로고
    • Transgenic model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: Interaction of c-myc and transforming growth factor α in hepatic oncogenesis
    • Murakami H, Sanderson ND, Nagy P, et al. Transgenic model for synergistic effects of nuclear oncogenes and growth factors in tumorigenesis: interaction of c-myc and transforming growth factor α in hepatic oncogenesis. Cancer Res 1993; 53: 1719-1723.
    • (1993) Cancer Res , vol.53 , pp. 1719-1723
    • Murakami, H.1    Sanderson, N.D.2    Nagy, P.3
  • 68
    • 0023127653 scopus 로고
    • Expression and characterization of transforming growth factor α precursor protein in transfected mammalian cells
    • Gentry LE, Twardzik DR, Lim GJ, Ranchalis JE, Lee DC. Expression and characterization of transforming growth factor α precursor protein in transfected mammalian cells. Mol Cell Biol 1987; 7: 1585-1591.
    • (1987) Mol Cell Biol , vol.7 , pp. 1585-1591
    • Gentry, L.E.1    Twardzik, D.R.2    Lim, G.J.3    Ranchalis, J.E.4    Lee, D.C.5
  • 69
    • 0026596801 scopus 로고
    • Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation
    • Evarts RP, Nakatsukasa H, Marsden ER, Hu Z, Thorgeirsson SS. Expression of transforming growth factor-alpha in regenerating liver and during hepatic differentiation. Mol Carcinog 1992; 5: 25-31.
    • (1992) Mol Carcinog , vol.5 , pp. 25-31
    • Evarts, R.P.1    Nakatsukasa, H.2    Marsden, E.R.3    Hu, Z.4    Thorgeirsson, S.S.5
  • 70
    • 0025607961 scopus 로고
    • Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues
    • Wright NA, Poulsom R, Stamp GWH, et al. Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues. J Pathol 1990; 162: 279-284.
    • (1990) J Pathol , vol.162 , pp. 279-284
    • Wright, N.A.1    Poulsom, R.2    Stamp, G.W.H.3
  • 73
    • 0021248961 scopus 로고
    • Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters
    • Bursch W, Lauer B. Timmermann-Trosiener I, et al. Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 1984; 5: 453-458.
    • (1984) Carcinogenesis , vol.5 , pp. 453-458
    • Bursch, W.1    Lauer, B.2    Timmermann-Trosiener, I.3
  • 74
    • 0025828052 scopus 로고
    • Liver tumor promotion: Effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-β1 expression
    • Jirtle RL, Meyer SA. Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-β1 expression. Dig Dis Sci 1991; 36: 659-668.
    • (1991) Dig Dis Sci , vol.36 , pp. 659-668
    • Jirtle, R.L.1    Meyer, S.A.2
  • 75
    • 0028206176 scopus 로고
    • Colocalized alterations in connexin 32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters
    • Neveu MJ, Babcock KL, Hertzberg EL, et al. Colocalized alterations in connexin 32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters. Cancer Res 1994; 54: 3145-3152.
    • (1994) Cancer Res , vol.54 , pp. 3145-3152
    • Neveu, M.J.1    Babcock, K.L.2    Hertzberg, E.L.3
  • 76
    • 0027978109 scopus 로고
    • Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital
    • Jirtle RL, Hankins GR, Reisenbichler H, Boyer IJ. Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital. Carcinogenesis 1994; 15: 1473-1478.
    • (1994) Carcinogenesis , vol.15 , pp. 1473-1478
    • Jirtle, R.L.1    Hankins, G.R.2    Reisenbichler, H.3    Boyer, I.J.4
  • 77
    • 0025118259 scopus 로고
    • Liver tumor promoters stimulate growth of transplanted hepatocellular carcinomas
    • Seglen PO, Saeterm G, Schwarze PE. Liver tumor promoters stimulate growth of transplanted hepatocellular carcinomas. Hepatology 1990; 12: 295-300.
    • (1990) Hepatology , vol.12 , pp. 295-300
    • Seglen, P.O.1    Saeterm, G.2    Schwarze, P.E.3
  • 78
    • 0027892873 scopus 로고
    • Collaboration between growth factors and diverse chemical carcinogens in hepatocarcinogenesis of transforming growth factor α transgenic mice
    • Takagi H, Sharp R, Takayama H, et al. Collaboration between growth factors and diverse chemical carcinogens in hepatocarcinogenesis of transforming growth factor α transgenic mice. Cancer Res. 1993; 53: 4329-4336.
    • (1993) Cancer Res. , vol.53 , pp. 4329-4336
    • Takagi, H.1    Sharp, R.2    Takayama, H.3
  • 80
    • 0027246159 scopus 로고
    • Response of phenobarbital- and ciprofibrate-exposed hepatocytes to growth factors in type I collagen gels
    • Lindroos P, Michalopoulos GK. Response of phenobarbital- and ciprofibrate-exposed hepatocytes to growth factors in type I collagen gels. Carcinogenesis 1993; 14: 731-735.
    • (1993) Carcinogenesis , vol.14 , pp. 731-735
    • Lindroos, P.1    Michalopoulos, G.K.2
  • 81
    • 0025766290 scopus 로고
    • Selective amplification of periportal transitional cells precedes formation of hepatocellular carcinoma in SV40 large tag transgenic mice
    • Schirmacher P, Held WA, Yang D, Biempica L, Rogler CE. Selective amplification of periportal transitional cells precedes formation of hepatocellular carcinoma in SV40 large tag transgenic mice. Am J Pathol 1991; 139: 231-241.
    • (1991) Am J Pathol , vol.139 , pp. 231-241
    • Schirmacher, P.1    Held, W.A.2    Yang, D.3    Biempica, L.4    Rogler, C.E.5
  • 82
    • 0023767641 scopus 로고
    • Cellular distribution of c-myc transcripts during chemical carcinogenesis in rats
    • Nagy P, Evarts RP, Marsden E, Roach J, Thorgeirsson SS. Cellular distribution of c-myc transcripts during chemical carcinogenesis in rats. Cancer Res 1988; 48: 5522-5527.
    • (1988) Cancer Res , vol.48 , pp. 5522-5527
    • Nagy, P.1    Evarts, R.P.2    Marsden, E.3    Roach, J.4    Thorgeirsson, S.S.5
  • 83
    • 0029043171 scopus 로고
    • Overexpression of c-met protooncogene product and raised Ki67 index in hepatocellular carcinomas with respect to benign conditions
    • Grigioni WF, Fiorentino M, D'Errico A, et al. Overexpression of c-met protooncogene product and raised Ki67 index in hepatocellular carcinomas with respect to benign conditions. Hepatology 1995; 21: 1543-1546.
    • (1995) Hepatology , vol.21 , pp. 1543-1546
    • Grigioni, W.F.1    Fiorentino, M.2    D'Errico, A.3
  • 84
    • 0025384670 scopus 로고
    • Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene
    • Iyer A, Kmiecik TE, Park M, et al. Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene. Cell Growth Differ 1990; 1: 87-95.
    • (1990) Cell Growth Differ , vol.1 , pp. 87-95
    • Iyer, A.1    Kmiecik, T.E.2    Park, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.