EBV induces proliferation of immature human thymocytes in an IL-2-mediated response

Journal of Immunology

Volumn 156, Issue 11, 1996, Pages 4217-4223

  Todd, Scott C ^a   Tsoukas, Constantine D ^a,b,c  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; INTERLEUKIN 2;

ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNITY; CELL PROLIFERATION; CELLULAR IMMUNITY; EPSTEIN BARR VIRUS; ETIOLOGY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; THYMOCYTE; VIRUS CARCINOGENESIS;

ANTIBODIES, BLOCKING; CELL AGGREGATION; CELL DIVISION; CHILD; HERPESVIRUS 4, HUMAN; HUMANS; INTERLEUKIN-2; KINETICS; LYMPHOCYTE ACTIVATION; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, COMPLEMENT 3D; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; VIRAL MATRIX PROTEINS;

EID: 0029901624     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Epstein, M. A., and B. G. Achong. 1977. Recent progress in Epstein-Barr virus research. Annu. Rev. Microbiol. 31:421.
2. Joske, D., and H. Knecht. 1993. Epstein-Barr virus in lymphomas: a review. Blood Rev. 7:215.
3. Straus, S. E., J. I. Cohen, G. Tosato, and J. Meier. 1993. Epstein-Barr virus infections: biology, pathogenesis, and management. Ann. Intern. Med. 118:45.
4. Klein, G. 1994. Epstein-Barr virus strategy in normal and neoplastic B cells. Cell 77:791.
5. Jones, J. F., S. Shurin, C. Abramowsky, R. R. Tubbs, C. G. Sciotto, R. Wahl, J. Sands, D. Gottman, B. Z. Katz, and J. Sklar. 1988. T-cell lymphomas containing Epstein-Barr viral DNA in patients with chronic Epstein-Barr virus infections. N. Engl. J. Med. 318:713.
6. Tsoukas, C. D., and J. D. Lambris. 1993. Expression of EBV/C3d receptors on T cells: biological significance. Immunol. Today 14:56.
7. Luka, J., Z. E. Deeb, D. P Hartmann, B. Jenson, and G. R. Pearson. 1988. Detection of antigens associated with Epstein-Barr virus replication in extracts from biopsy specimens of nasopharyngeal carcinomas. J. Natl. Cancer Inst. 80: 1164.
8. Nalesnik, M. A. 1991. Lymphoproliferative disease in organ transplant recipients. Springer Semin. Immunopathol. 13:199.
9. Brousset, P., H. Knecht, B. Rubin, E. Drouet, S. Chittal, F. Meggetto, T. A. Saati, E. Bachmann, G. Denoyel, A. Sergeant, and G. Delsol. 1993. Demonstration of Epstein-Barr virus replication in Reed-Sternberg cells of Hodgkin's disease. Blood 82:872.
10. Fingeroth, J. D., J. J. Weis, T. F. Tedder, J. L. Strominger, P. A. Biro, and D. T. Fearon. 1984. Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proc. Natl. Acad. Sci. USA 81:4510.
11. Frade, R., M. Barel, B. Ehlin-Henriksson, and G. Klein. 1985. gp140, the C3d receptor of human B lymphocytes, is also the Epstein-Barr virus receptor. Proc. Natl. Acad. Sci. USA 82:1490.
12. Nemerow, G. R., R. Wolfert, M. E. McNaughton, and N. R. Cooper. 1985. Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2). J. Virol. 55:347.
13. Hurley, E. A., and D. A. Thorley-Lawson. 1988. B cell activation and the establishment of Epstein-Barr virus latency. J. Exp. Med. 168:2059.
14. Alfieri, C., M. Birkenbach, and E. Kieff. 1991. Early events in Epstein-Barr virus infection of human B lymphocytes. Virology 181:595.
15. Tomkinson, B. E., D. K. Wagner, D. L. Nelson, and J. L. Sullivan. 1987. Activated lymphocytes during acute Epstein-Barr virus infection. J. Immunol. 139: 3802.
16. Tsoukas, C. D., and J. D. Lambris. 1988. Expression of CR2/EBV receptors on human thymocytes detected by monoclonal antibodies. Eur. J. Immunol. 18:1299.
17. Watry, D., J. A. Hedrick, S. Siervo, G. Rhodes, J. J. Lamberti, J. D. Lambris, and C. D. Tsoukas. 1991. Infection of human thymocytes by Epstein-Barr virus. J. Exp. Med. 173:971.
18. Delibrias, C. C., A. Mouhoub, E. Fischer, and M. D. Kazatchkine. 1994. CR1(CD35) and CR2(CD21) complement C3 receptors are expressed on normal human thymocytes and mediate infection of thymocytes with opsonized human immunodeficiency virus. Eur. J. Immunol. 24:2784.
19. Kaufman Paterson, R. L., C. A. Kelleher, J. E. Streib, T. D. Amankonah, J. W. Xu, J. F. Jones, and E. W. Gelfand. 1995. Activation of human thymocytes after infection with EBV. J. Immunol. 154:1440.
20. Kelleher, C. A., R. K. Paterson, D. H. Dreyfus, J. E. Streib, J. W. Xu, K. Takase, J. F. Jones, and E. W. Gelfand. 1995. Epstein-Barr virus replicative gene transcription during de novo infection of human thymocytes: simultaneous early expression of BZLF-1 and its repressor RAZ. Virology 208:685.
21. Spits, H. 1994. Early stages in human and mouse T-cell development. Curr. Opin. Immunol. 6:212.
22. Robey, E., and B. J. Fowlkes. 1994. Selective events in T cell development. Annu. Rev. Immunol. 12:675.
23. + human thymocytes proliferate in response to superantigen staphylococcal enterotoxin B. J. Immunol. 153:2038.
24. Wahl, S. M., D. L. Rosenstreich, and J. J. Oppenheim. 1976. Separation of human lymphocytes by E rosette sedimentation. In In Vitro Methods in Cell-Mediated and Tumor Immunity. B. R. Bloom and J. R. David, eds. Academic Press, New York, p. 231.
25. Hedrick, J. A., Z. Lao, S. G. Lipps, Y. Wang, S. C. Todd, J. D. Lambris, and C. D. Tsoukas. 1994. Characterization of a 70-kDa, EBV gp350/220-binding protein on HSB-2 T cells. J. Immunol. 153:4418.
26. Martin, L. H., F. Calabi, F. A. Lefebvre, C. A. Bilsland, and C. Milstein. 1987. Structure and expression of the human thymocyte antigens CD1a, CD1b and CD1c. Proc. Natl. Acad. Sci. USA 84:9189.
27. + thymocytes in suspension culture by extrathymic antigen-presenting cells. Nature 351:150.
28. + precursor stage. Nature 334:620.
29. + thymocytes. Nature 333:742.
30. Vasquez, N. J., J. Kaye, and S. M. Hedrick. 1992. In vivo and in vitro deletion of double-positive thymocytes. J. Exp. Med. 175:1307.
31. Ring, C. J. A. 1994. The B cell-immortalizing functions of Epstein-Barr virus. J. Gen. Virol. 75:1.
32. Veronese, M. L., A. Veronesi, E. D'Andrea, A. Del Mistro, S. Indraccolo, M. R. Mazza, M. Mion, R. Zamarchi, C. Menin, M. Panozzo, A. Amadori, and L. Chieco-Bianchi. 1992. Lymphoproliferative disease in human peripheral blood mononuclear cell-injected mice: i.t. lymphocyte requirement for B cell tumor generation. J. Exp. Med. 176:1763.
33. Landry, D., L. Doyon, J. Poudrier, M. Lafontaine, M. Pelletier, and S. Montplaisir. 1990. Accessory function of human thymic dendritic cells in Con A-induced proliferation of autologous thymocyte subsets. J. Immunol. 144:836.
34. Lindhout, E., A. Lakeman, M. L. C. M. Mevissen, and C. de Groot. 1994. Functionally active Epstein-Barr virus-transformed follicular dendritic cell-like lines. J. Exp. Med. 179:1173.
35. Inoue, N., S. Harada, N. Miyasaka, A. Oya, and K. Yanagi. 1991. Analysis of antibody titers to Epstein-Barr virus nuclear antigens in sera of patients with Sjögren's syndrome and with rheumatoid arthritis. J. Infect. Dis. 164:22.
36. Marchini, B., M. P. Dolcher, A. Sabbatini, G. Klein, and P. Migliorini. 1994. Immune response to different sequences of the EBNA I molecule in Epstein-Barr virus-related disorders and in autoimmune diseases. J. Autoimmun. 7:179.
37. F ox, R. I., M. Luppi, H. I. Kang, and P. Pisa. 1991. Reactivation of Epstein-Barr virus in Sjögren's syndrome. Springer Semin. Immunopathol. 13:217.
38. Alvarez-Vallina, L., A. Gonzalez, F. Gambon, M. Kreisler, and F. Diaz-Espada. 1993. Delimitation of the proliferative stages in the human thymus indicates that cell expansion occurs before the expression of CD3 (T cell receptor). J. Immunol. 150:8.
39. Vandekerckhove, B. A. E., A. Barcena, D. Schols, S. Mohan-Peterson, H. Spits, and M. G. Roncarolo. 1994. In vivo cytokine expression in the thymus. J. Immunol. 152:1738.
40. Carding, S. R., A. C. Mayday, and K. Bottomly. 1991. Cytokines in T-cell development. Immunol. Today 12:239.