The significance of vasoactive intestinal polypeptide (VIP) in immunomodulation

Advances in Neuroimmunology

Volumn 6, Issue 1, 1996, Pages 5-27

  Bellinger, D L ^a   Lorton, D ^a   Brouxhon, S ^a   Felten, S ^a   Felten, D L ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANTIBODY PRODUCTION; AUTOCRINE EFFECT; CELL POPULATION; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOMODULATION; IMMUNOREGULATION; REVIEW; TARGET CELL; TISSUE SPECIFICITY;

EID: 0029901533     PISSN: 09605428     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-5428(96)00008-3     Document Type: Article

References (171)

1. 3 Eur. J. Biochem. 183 1989 263 267
2. L.D. Alexander L.D. Sanders Involvement of vasopressin and corticotropin-releasing hormone in VIP-and PHI-induced secretion of ACTH and corticosterone Neuropeptides 28 1995 167 173
3. L.D. Alexander L.D. Sanders Vasoactive intestinal peptide stimulates ACTH and corticosterone released after injection into the PVN Regul. Pept. 51 1994 221 227
4. J. Aliakbari S.P. Sreedharan C.W. Turck E.J. Goetzl Selective localization of vasoactive intestinal peptide and substance P in human eosinophils Biochem. Biophys. Res. Commun. 148 1987 1440 1445
5. B.J. Arey M.E. Freeman Oxytocin, vasoactive intestinal peptide and serotonin regulate the mating-induced surges of prolactin secretion in the rat Endocrinology 126 1990 279 284
6. E.A. Beed M.S. O'Dorisio T.M. O'Dorisio T.S. Gaginella Demonstration of a functional receptor for vasoactive intestinal polypeptide on Molt 4b lymphoblasts Regul. Pept. 6 1983 1 12
7. D.L. Bellinger D.J. Earnest M. Gallagher D.L. Felten Presence and availability of VIP in primary and secondary lymphoid organs Soc. Neurosci. Abstr. 18 1992 1009 (abstract)
8. D.L. Bellinger D. Lorton T. Romano J.A. Olschowka S.Y. Felten D.L. Felten Neuropeptide innervation of lymphoid organs Ann. N.Y. Acad. Sci. 594 1990 17 33
9. H. Berisha H.D. Foda H. Sakakibara M. Trotz H. Pakbaz S.I. Said Vasoactive intestinal peptide prevents lung injury due to xanthine/xanthine oxidase Am. J. Physiol. 259 1990 L151 L155
10. A.M. Blum R. Mathew G.A. Cook A. Metwall R. Felman J.V. Weinstock Murine mucosal T cells have VIP receptors functionally distinct from those on intestinal epithelial cells J. Neuroimmunol. 39 1992 101 108
11. L. Bondesson K. Norolind S. Liden G. Gafvelin E. Theodorsson V. Mutt Dual effects of vasoactive intestinal peptide (VIP) on leucocyte migration Acta. Physiol. Scand. 141 1991 477 481
12. R. Boudard M. Bastide Inhibition of mouse T-cell proliferation by CGRP and VIP: Effects of these neuropeptides on IL-2 production and cAMP synthesis J. Neurosci. Res. 29 1991 29 41
13. J.R. Calvo J.M. Guerrero P. Molinero R. Blasco R. Goberna Interaction of vasoactive intestinal peptide (VIP) with human peripheral blood lymphocytes: specific binding and cyclic AMP production Gen. Pharmac. 17 1986 185 189
14. J.R. Calvo P. Molinero J. Jiminez R. Goderna J.M. Guerrero Interaction of vasoactive intestinal peptide (VIP) with rat lymphoid cells Peptides 7 1986 177 181
15. J.R. Calvo M.L. Montilla J.M. Guerrero J.J. Segura Expression of VIP receptors in mouse peritoneal macrophages: functional and molecular characterization J. Neuroimmunol. 50 1994 85 93
16. A. Cauvin A. Vandermeers M.-C. Vandermeers-Piret J. Rathe P. Robberecht J. Christophe Variable distribution of three molecular forms of PHI in rat tissue: identification of the large form as PHV(1–42) Endocrinology 125 1989 2645 2655
17. P.P.-J. Cheng S.P. Sreedharan J.L. Kishiyama E.J. Goetzl The SKW 6.4 line of human B lymphocytes specifically binds and responds to vasoactive intestinal peptide Immunology 79 1993 64 68
18. V. Chevendra L.C. Weaver Distribution of neuropeptide Y, vasoactive intestinal peptide and somatostatin in populations of postganglionic neurons innervating the rat kidney, spleen and intestine Neuroscience 50 1992 727 743
19. M.K. Church S. El-Lati J.P. Caulfield Neuropeptide-induced secretion from human skin mast cells Int. Arch. Allergy Appl. Immunol. 94 1991 310 318
20. H.J. Cooke Neurobiology of the intestinal mucosa Gastroenterology 90 1986 1057 1081
21. A. Couvineau B. Amiranoff M. Laburthe Solubilization of the liver vasoactive peptide receptor. Hydrodynamic characterization of evidence for an association with a functional GTP regulatory protein J. Biol. Chem. 261 1986 14482 14489
22. S.W. Craig J.J. Cebra Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit J. Exp. Med. 134 1971 188 200
23. E. Crivellato D. Damiani F. Mallardi L. Travan Suggestive evidence for a microanatomical relationship between mast cells and nerve fibers containing substance P, calcitonin gene-related peptide, vasoactive intestinal polypeptide, and somatostatin in the rat mesentery Acta Anat. 141 1991 127 131
24. D. Cutz W. Chan N.S. Track A. Goth S.I. Said Release of vasoactive intestinal polypeptide in mast cells by histamine liberators Nature 275 1978 661 662
25. A. Danek M.S. O'Dorisio T.M. O'Dorisio J.M. George Specific binding sites for vasoactive intestinal polypeptide on nonadherent peripheral blood lymphocytes J. Immunol. 131 1983 1173 1177
26. J.P. Dehaye J. Winand C. Damien F. Gomez P. Poloczek P. Robberecht A. Vandermeers M.C. Vandermeers-Piret M. Stievenart J. Christophe Receptors involved in helodermin action on rat pancreatic acini Am. J. Physiol. 251 1986 G602 G610
27. R.D. Dey J. Hoffpauir S.I. Said Colocalization of vasoactive intestinal peptide- and substance P-containing nerves in cat bronchi Neuroscience 24 1988 275 281
28. R.D. Dey S.I. Said Lung peptides and the pulmonary circulation S.I. Said The Pulmonary Circulation 1985 Futura Publishing New York 101 122
29. R.D. Dey W.A. Shannon Jr. S.I. Said Localization of VIP-immunoreactive nerves in airways and pulmonary vessels of dogs, cats, and human subjects Cell Tissue Res. 220 1981 231 238
30. V. Di Marzo J.R. Tippins H.R. Morris The effect of vasoactive intestinal peptide and calcitonin gene-related peptide on peptidoleukotriene release from platelet activating factor stimulated rat lungs and ionophore stimulated guinea pig lungs Biochem. Int. 13 1986 933 942
31. P. Drew D. Shearman Vasoactive intestinal peptide: A neurotransmitter which reduces human NK cell activity and increases Ig synthesis Aust. J. Exp. Biol. Med. Sci. 63 1985 313 318
32. E. Ekblad C. Winther R. Ekman R. Hakanson F. Sundler Projections of peptide-containing neurons in rat small intestine Neuroscience 20 1987 169 188
33. J. Epelbaum L. Tapia-Arancibia J. Besson W. Rotsztein C. Kordon Vasoactive intestinal peptide inhibits release of somatostatin from hypothalamus in vitro Eur. J. Pharmacol. 58 1979 493 495
34. T. Epsevik T.S. Figari M.R. Shalaby M.R. Lackides G.D. Lewis H.M. Shepard M.A. Palladino Inhibition of cytokine production by cyclosporin A and transforming growth factor β J. Exp. Med. 166 1987 571 576
35. J. Fahrenkrug T. Bek J.M. Lundberg T. Hokfelt VIP and PHI in cat neurons: colocalization but variable tissue content possibly due to differential processing Regul. Pept. 12 1985 21 34
36. J. Fahrenkrug P.C. Emson D. Ronnov-Jenssen Characterization and regional distribution of prepro-VIP derived peptides in the normal human brain and gut Regul. Pept. 26 1989 155 (abstract)
37. D.L. Felten S.Y. Felten S.L. Carlson J.A. Olschowka S. Livnat Noradrenergic and peptidergic innervation of lymphoid tissue J. Immunol. 135 1985 755s 765s
38. R. Finch S.P. Sreedharan E.J. Goetzl High affinity receptors for vasoactive intestinal peptide on human myeloma cells J. Immunol. 142 1989 1977 1981
39. T. Fink E. Weihe Multiple neuropeptides in nerves supplying mammalian lymph nodes: messenger candidates for sensory and autonomic neuroimmunomodulation? Neurosci. Lett. 90 1988 39 44
40. J. Fisher M.S. O'Dorisio T.M. O'Dorisio M.R. Grever The use of VIP and ADA as biochemical markers in leukemia D. Yohn J. Blakeslee Advances in Comparative Leukemia Research 1982 Elsevier New York 513 514
41. B. Fjellner O. Hagermark Studies on pruritogenic and histamine-releasing effects of some putative peptide neurotransmitters Acta Dermatovener (Stockholm) 61 1981 245 250
42. H.D. Foda T. Iwanaga L.W. Liu S.I. Said Vasoactive intestinal peptide protects against HCI-induced pulmonary edema in rats Ann. N.Y. Acad. Sci. 527 1988 633 636
43. J.B. Furness M. Costa Types of nerves in the enteric nervous system Neuroscience 5 1980 1 20
44. K. Fuxe T. Hokfelt S.I. Said V. Mutt Vasoactive intestinal polypeptide and the nervous system: immunohistochemical evidence for localization in central and peripheral neurons, particularly intracortical neurons in the cerebral cortex Neurosci. Lett. 5 1977 241 246
45. D. Ganea L. Sun Vasoactive intestinal peptide downregulates the expression of IL-2 but not of IFNγ from stimulated murine T lymphocytes J. Neuroimmunol. 47 1993 147 158
46. 2 receptors in human THP-1 monocytes/macrophages: a possible role in the regulation of superoxide anions production Regul. Pept. 26 1989 158 (abstract)
47. A.G. Gilman Guanine nucleotide binding regulatory proteins and dual control of adenylate cyclase J. Clin. Invest. 73 1984 1 4
48. C.H. Ginsburg J.T. Dambrauskas K.A. Ault Z.M. Falchuk Impaired natural killer cell activity in patients with inflammatory bowel disease: Evidence for a qualitative defect Gastroenterology 85 1983 846 851
49. E.J. Goetzl S.P. Sreedharan C.W. Turck Structurally distinctive vasoactive intestinal peptides from rat basophilic leukemia cells J. Biol. Chem. 263 1988 9083 9086
50. R.P. Gomariz M. De La Fuente A. Hernanz J. Leceta Occurrence of vasoactive intestinal peptide (VIP) in lymphoid organs Ann. N.Y. Acad. Sci. 650 1992 13 18
51. B. Gomariz M. Delgado J.R. Naranjo B. Mellstrom A. Tormo F. Mata J. Leceta VIP gene expression in rat thymus and spleen Brain Behav. Immun. 7 1993 271 278
52. R.P. Gomariz J. Leceta E. Garrido T. Garrido M. Delgado Vasoactive intestinal peptide (VIP) mRNA expression in rat T and B lymphocytes Regul. Pept. 50 1994 177 184
53. I. Gozes Biosynthesis and regulation. The vasoactive intestinal peptide gene Ann. N.Y. Acad. Sci. 527 1988 77 87
54. J.M. Guerrero J.C. Prieto J.R. Calvo R. Goberna Activation of cyclic AMP-dependent protein kinase by VIP in blood mononuclear cells Peptides 5 1984 371 373
55. J.M. Guerrero J.C. Prieto F.L. Elorza R. Ramirez R. Goberna Interaction of vasoactive intestinal peptide with human blood mononuclear cells Mol. Cell. Endocrinol. 21 1981 151 160
56. K.J. Hardy B. Manger M. Newton J.D. Stobo Molecular events involved in regulating human interferon-gamma gene expression during T cell activation J. Immunol. 138 1987 2353 2358
57. S. Ichikawa S.P. Sreedharan E.J. Goetzl R.L. Owen Immunohistochemical localization of peptidergic nerve fibers and neuropeptide receptors in Peyer's patches of the cat ileum Regul. Pept. 54 1994 385 395
58. Y. Inoue K. Kaku T. Kaneko N. Yanaihara T. Kanno Vasoactive intestinal peptide binding to specific receptors on rat parotid acinar cells induces amylase secretion accompanied by intracellular accumulation of cyclic adenosine 3'-5'-monophosphate Endocrinology 116 1985 686 692
59. T. Ishihara R. Shigemoto K. Mori K. Takahashi S. Nagata Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide Neuron 8 1992 811 819
60. C. Ishioka A. Yoshida H. Kimata H. Mikawa Vasoactive intestinal peptide stimulates immunoglobulin production and growth of human B cells Clin. Exp. Immunol. 87 1992 504 508
61. J.A. Johnston D.D. Taub A.R. Lloyd K. Conlon J.J. Oppenheim D.J. Kevlin Human T lymphocyte chemotaxis and adhesion induced by vasoactive intestinal peptide J. Immunol. 153 1994 1762 1768
62. T. Kaneko P.Y. Cheng H. Oka N. Oda N. Yanaihara C. Yanaihara Vasoactive intestinal polypeptide stimulates adenylate cyclase and serotonin N -acetyl-transferase activities in rat pineal in vitro Biomed. Res. 1 1980 84 87
63. Y. Kato Y. Iwasaki J. Iwasaki H. Abe H. Yanaihara T. Nakajima Y. Ibata Prolactin release by vasoactive intestinal polypeptide in rats Endocrinology 103 1978 554 558
64. H. Kimata M. Fujimoto Vasoactive intestinal peptide specifically induces human IgA1 and IgA2 production Eur. J. Immunol. 24 1994 2262 2265
65. 2 production in immature human fetal B cells and pre-B cells by vasoactive intestinal peptide Blood 85 1995 2098 2104
66. 4 production in atopic patients J. Immunol. 150 1993 4630 4640
67. H. Kimata A. Yoshida C. Ishioka H. Mikawa Differential effect of vasoactive intestinal peptide, somatostatin, and substance P on human IgE and IgG subclass production Cell Immunol. 144 1992 429 442
68. T.R. Koch J.A. Carney V.L.W. Go Distribution and quantitation of gut neuropeptides in normal intestine and inflammatory bowel disease Dig. Dis. Sci. 32 1987 369 376
69. T.R. Koch J.A. Carney V.L.W. Go J.H. Szurszewski Altered inhibitory innervation of circular smooth muscle in Crohn's colitis: association with decreased vasoactive intestinal polypeptide levels Gastroenterology 98 1990 1437 1444
70. C. Kroc A. Gores V. Go Gastrointestinal regulatory peptides modulate mouse lymphocyte functions under serum free conditions in vitro Immunol. Invest. 15 1986 103 111
71. C. Kroc A. Gores V. Go Gastrointestinal regulatory peptides modulate in vitro immune reactions of mouse lymphocytes Clin. Immunol. Immunopathol. 39 1986 308 318
72. M. Kurosawa T. Ishizuka Inhibitory effects of vasoactive intestinal peptide on superoxide anion formation by N -formyl-methionyl-leucyl-phenylalanine-activated inflammatory cells in vitro Int. Arch. Allergy Appl. Immunol. 100 1993 28 34
73. M. Laburthe B. Amiranoff N. Boige C. Royer-Fessard K. Tatemoto L. Moroder Interaction of GRF with VIP receptors and stimulation of adenylate cyclase in rat and human intestinal epithelial membranes. Comparison with PHI and secretin FEBS Lett. 159 1983 89 92
74. 1 hGRF is a competitive VIP antagonist in the rat Mol. Pharmacol. 29 1986 23 27
75. C.B. Lacey R.P. Elde V.S. Seybold Localization of vasoactive intestinal peptide binding sites in the thymus and bursa of fabricius of the chick Peptides 12 1991 383 391
76. J.-S. Lacroix S. Auberson D.R. Morel E. Theodorsson T. Hokfelt J.M. Lundberg Vascular control of the pig nasal mucosa: distribution and effect of somatostatin in relation to noradrenaline and neuropeptide Y Regul. Pept. 40 1992 373 387
77. A. Laitinen M. Partanen A. Hernonen M. Pelto-Huikko L.A. Laitinen VIP-like immunoreactive nerves in human respiratory tract Histochemistry 82 1985 313 319
78. I. Loren P.C. Emson J. Fahrenkrug J. Bjorklund R. Alumets R. Hakanson F. Sundler Distribution of vasoactive intestinal polypeptide in the rat and mouse brain Neuroscience 4 1979 1953 1976
79. J.M. Lundberg A. Änggård J. Pernow T. Hökfelt Neuropeptide Y-, substance P- and VIP-immunoreactive nerves in cat spleen in relation to autonomic vascular and volume control Cell Tissue Res. 239 1985 9 18
80. J.M. Lundberg J. Fahrenkrug T. Hokfelt C.-R. Martling K. Larsson K. Tatemoto A. Änggård Co-existence of peptide HI (PHI) and VIP in nerves regulating blood flow and bronchial smooth muscle tone in various mammals including man Peptide 5 1984 593 606
81. J.M. Lundberg J. Fahrenkrug O. Larsson A. Änggård Corelease of vasoactive intestinal and peptide histidine isoleucine in relation to atropine-resistant vasodilation in cat submandibular salivary gland Neurosci. Lett. 52 1984 37 42
82. J.M. Lundberg T. Hokfelt J. Kewenter G. Peterson H. Ahlman R. Edwin A. Dahlstrom G. Nilsson L. Terenius J. Rehfeld R. Elde S.I. Said Substance P-, VIP-, and enkephalin-like immunoreactivity in the human vagus nerve Gastroenterology 77 1979 468 471
83. J.M. Lundberg T. Hokfelt G. Nilsson L. Terenius J. Rehfeld R. Elde S. Said Peptide neurons in the vagus, splanchnic and sciatic nerves Acta Physiol. Scand. 104 1978 499 501
84. I. Lygren A. Revhaug P.G. Burhol K.E. Giercksky T.G. Jenssen Vasoactive intestinal polypeptide and somatostatin in leukocytes Scand. J. Clin. Lab. Invest. 44 1984 347 351
85. M. Madden C.F. Johnston J.E.S. Ardill K.D. Buchanan J.M. Bridges Vasoactive intestinal polypeptide as a biochemical marker for polymorphonuclear leukocytes J. Lab. Clin. Med. 99 1981 295 296 ( Lett. )
86. R.C. Mathew G.A. Cook A.M. Blum A. Metwall R. Felman J.V. Weinstock Vasoactive intestinal peptide stimulates T lymphocytes to release IL-5 in murine schistosomiasis mansoni infection J. Immunol. 148 1992 3572 3577
87. G. Mayrhofer Physiology of the intestinal immune system T.J. Newby C.R. Stokes Local Immune Responses of the Gut 1984 CRC Press Boca Raton 1 96
88. A. Metwall A. Blum R. Mathew M. Sandor R.G. Lynch J.V. Weinstock Modulation of T lymphocyte proliferation in mice infected with Schistosoma mansoni: VIP suppresses mitogen- and antigen-induced T cell proliferation possibly by inhibiting IL-2 production Cell. Immunol. 149 1993 11 23
89. E. Mezey J.Z. Kiss Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion Proc. Natl Acad. Sci. (USA) 82 1985 245 247
90. T.C. Moore Modification of lymphocyte traffic by vasoactive neurotransmitter substances Immunology 52 1984 511 518
91. T.C. Moore C.H. Spruck S.I. Said Depression of lymphocyte traffic in sheep by vasoactive intestinal peptide (VIP) Immunology 64 1988 475 478
92. R.F. Murphy R.S. France M. Chen M. Vorhees S.N. Jaffe Immunoreactivities of vasoactive intestinal peptide (VIP) and glucagon in leucocytes from leukemic patients J. Lab. Clin. Med. 99 1981 294 295 ( Lett. )
93. G.A. Neil A. Blum J.V. Weinstock Substance P but not vasoactive intestinal peptide modulates immunoglobulin secretion in murine schistosomiasis Cell. Immunol. 135 1991 394 401
94. D.A. Nio R.N. Moylan J.K. Roche Modulation of T lymphocyte function by neuropeptides. Evidence for their role as local immunoregulatory elements J. Immunol. 150 1993 5281 5288
95. D. Nohr E. Weihe The neuroimmune link in the bronchus-associated lymphoid tissue (BALT) of cat and rat: peptides and neural markers Brain Behav. Immun. 5 1991 84 101
96. K. Nordlind V. Mutt Influence of β-endorphin, somatostatin, substance P and VIP on proliferative response of human peripheral blood T cells to mercuric chloride Int. Arch. Allergy Appl. Immunol. 80 1986 326 328
97. M.S. O'Dorisio L.B. Campolito Comparison of vasoactive intestinal peptide-mediated protein phosphorylation in human lymphoblasts and colonic epithelial cells Mol. Immunol. 26 1989 583 590
98. M.S. O'Dorisio N.S. Hermina T.M. O'Dorisio S.P. Balcerzak Vasoactive intestinal polypeptide modulation of lymphocyte adenylate cyclase J. Immunol. 127 1981 2551 2554
99. M.S. O'Dorisio T.M. O'Dorisio S. Cataland S.P. Balcerzak VIP as biochemical marker for PMNs J. Lab. Clin. Med. 99 1981 297 298 ( Lett. )
100. M.S. O'Dorisio T. O'Dorisio S. Cotland S.P. Bakerzak Vasoactive intestinal polypeptide as a biochemical marker for polymorphonuclear leukocytes J. Lab. Clin. Med. 96 1980 666 672
101. M.S. O'Dorisio B.T. Shannon D.J. Fleshman L.B. Campolito Identification of high affinity receptors for vasoactive intestinal peptide on human lymphocytes of B cell lineage J. Immunol. 142 1989 3533 3536
102. M.S. O'Dorisio C. Wood G. Wenger L. Vasalo Cyclic AMP-dependent protein kinase in MOLT-4B lymphoblasts: identification by photoaffinity labeling and activation in intact cells by VIP and PHI J. Immunol. 134 1985 4078 4085
103. N. Ohkubo S. Miura H. Serizawa H.J. Yan H. Kimura H. Imaeda H. Tashiro M. Tsuchiya In vivo effect of chronic administration of vasoactive intestinal peptide on gut-associated lymphoid tissues in rats Regul. Pept. 50 1994 127 135
104. S. Ollerenshaw D. Jarvis A. Woolcock C. Sullivan T. Scheibner Absence of immunoreactive vasoactive intestinal polypeptide in tissue from the lungs of patients with asthma New Engl. J. Med. 320 1989 1244 1248
105. C.A. Ottaway In vitro alteration of receptors for vasoactive intestinal peptide changes the in vivo localization of mouse T cells J. Exp. Med. 160 1984 1054 1069
106. C.A. Ottaway Evidence for local neuromodulation of T cell migration in vivo Adv. Exp. Med. 186 1985 637 645
107. C.A. Ottaway Selective effects of vasoactive intestinal peptide on the mitogenic response of murine T cells Immunology 62 1987 291 297
108. C.A. Ottaway Vasoactive intestinal peptide as a modulator of lymphocyte and immune functions Ann. N.Y. Acad. Sci. 527 1988 486 500
109. C. Ottaway Vasoactive intestinal peptide and immune function R. Ader D.L. Felten N. Cohen second edition Psychoneuroimmunology 1991 Academic Press San Diego 225 262
110. C.A. Ottaway C. Bernaerts B. Chan G.R. Greenberg Specific binding of VIP to human circulating mononuclear cells Can. J. Physiol. Pharmacol. 61 1983 664 671
111. C.A. Ottaway G.R. Greenberg Interaction of vasoactive intestinal peptide with mouse lymphocytes: specific binding and the modulation of mitogen responses J. Immunol. 132 1984 417 423
112. C.A. Ottaway T. Lay G. Greenberg High affinity specific binding of vasoactive intestinal peptide to human circulating T cells, B cells and large granular lymphocytes J. Neuroimmunol. 29 1990 149 155
113. C.A. Ottaway D.L. Lewis S.L. Asa Vasoactive intestinal peptide-containing nerves in Peyer's patches Brain Behav. Immun. 1 1987 148 158
114. F. Pallone S. Fais B. Annibale M. Boirivant S. Morace G. Delle Fave Modulatory effects of somatostatin and vasoactive intestinal peptide on human intestinal lymphocytes Ann. N.Y. Acad. Sci. 594 1990 408 410
115. J.M. Palmer B. Greenwood Regional content of enteric substance P and vasoactive intestinal peptide during intestinal inflammation in the parasitized ferret Neuropeptides 25 1993 95 103
116. S. Paul Decreased selectivity of vasoactive intestinal peptide receptors by GTP Biochem. Pharmacol. 38 1989 699 702
117. C. Pedrera M. Lucas J. Bellido M.A. Lopez-Gonzalez Receptor-independent mechanisms are involved in the priming of neutrophil's oxidase by vasoactive intestinal peptide Regul. Pept. 54 1994 505 511
118. S. Peuriere C. Susini M. Alvinerie N. Vaysse L. Escoula Interactions between neuropeptides and dexamethasone on the mitogenic response of rabbit spleen lymphocytes Peptides 12 1991 645 651
119. J.M. Polak A.G.E. Pearse J.-C. Garaud S.R. Bloom Cellular localization of a vasoactive intestinal peptide in the mammalian and avian gastrointestinal tract Gut 15 1974 720 724
120. P. Popper C.R. Mantyh S.R. Vigna J.E. Magioos P.W. Mantyh The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes Peptides 9 1988 257 267
121. L. Probert J. de Mey J.M. Polak Distinct subpopulations of enteric p-type neurones contain substance P and vasoactive intestinal polypeptide Nature 294 1981 470 471
122. S. Provow G. Velicelebi Characterization and solubilization of vasoactive intestinal peptide receptors from rat lung membranes Endocrinology 120 1987 2442 2452
123. P. Robberecht A. Cauvin P. Gourlet J. Christophe Heterogeneity of VIP receptors Arch. Int. Pharmacodyn. 303 1990 51 66
124. P. Robberecht D.H. Coy P. De Neef J.-C. Camus M. Waelbroeck J. Christophe Specific labeling of high-affinity vasoactive intestinal peptide receptors in rat liver membranes by a growth hormone-releasing factor analog Neuroendocrinology 44 1986 108 111
125. 1 lymphoma cell membranes Regul. Pept. 26 1989 117 126
126. P. Robberecht P. De Neef M. Waelbroeck M. Tastenoy J. Christophe VIP and related peptides induce rapid homologous desensitization in the human lymphoma SUP T1 cell line Peptides 10 1989 441 446
127. P. Robberecht K. Tatemoto P. Chatelain M. Waelbroeck M. Delhaye G. Taton P. De Neef J.C. Camus D. Heuse J. Christophe Effects of PHI on vasoactive intestinal peptide receptors and adenylate cyclase activity in lung membranes. A comparison in man, rat, mouse and guinea-pig Regul. Pept. 4 1982 241 250
128. P. Robberecht E. Vervisch P. De Neef D.H. Coy J. Christophe Cholera toxin pretreatment of the human lymphoblastic cell line SUP T1 affects the selectivity of helodermin/VIP receptors Regul. Pept. 26 1989 177 (abstract)
129. P. Robberecht M. Waelbroeck D. Coy P. De Neef J.-C. Camus J. Christophe Comparative structural requirements of thirty GRF analogs for interaction with GRF- and VIP receptors and coupling to adenylate cyclase in rat adenopituitary, liver and pancreas Peptides 7 1986 53 59 ( Suppl. 1 )
130. P. Robberecht M. Waelbroeck P. De Neef J.C. Camus D.H. Coy J. Christophe Pharmacological characterization of VIP receptors in human lung membranes Peptides 9 1988 339 345
131. P. Robberecht M. Waelbroeck P. De Neef J.-C. Camus P. Gourlet J. Christophe Effect of freezing on the coupling of VIP receptors to adenylate cyclase in rat liver membranes Life Sci. 42 1988 505 510
132. 125I-helodermin of high-affinity VIP receptors in rat liver membranes FEBS Lett. 172 1984 55 58
133. P. Robberecht M. Waelbroeck P. De Neef M. Tastenoy P. Gourlet J. Cogniaux J. Christophe A new type of functional VIP receptor has an affinity for helodermin in human SUP-T1 lymphoblasts FEBS Lett. 228 1988 351 355
134. A.I. Roberts A. Panja R.E. Brolin E.C. Ebert Human intraepithelial lymphocytes. Immunomodulation and receptor binding of vasoactive intestinal peptide Dig. Dis. Sci. 36 1991 341 346
135. A. Robichon J.C. Marie Selective photolabeling of high and low affinity binding sites for vasoactive intestinal peptide (VIP): evidence for two classes of covalent VIP-receptor complexes in intestinal cell membranes Endocrinology 120 1987 978 985
136. A. Robichon S.P. Sreedharan J. Yang R.S. Shames E.C. Gronroos P.P.-J. Cheng E.J. Goetzl Induction of aggregation of Raji human B-lymphoblastic cells by vasoactive intestinal peptide Immunology 79 1993 574 579
137. M. Rola-Pleszczynski D. Bulduc A. St Pierre The effects of VIP on human NK cell function J. Immunology 135 1985 2659 2673
138. S.I. Said Influence of neuropeptides on airway smooth muscle Am. Rev. Respir. Dis. 136 1987 525 528 Suppl.
139. S.I. Said Vasoactive intestinal peptide in the lung Ann. N.Y. Acad. Sci. 527 1988 450 464
140. 2a S.I. Said Vasoactive Intestinal Peptide 1982 Raven Press New York 185 191
141. M. Schultzberg T. Hokfelt G. Nilsson L. Terenius J. Rehfeld M. Brown R. Elde M. Goldstein S. Said Distribution of peptide and catecholamine containing nerves in the gastrointestinal tract of rat and guinea pig Neuroscience 5 1980 689 744
142. R. Scicchitano J. Bienenstock A.M. Stanisz In vivo immunomodulation by the neuropeptide substance P Immunology 63 1988 733 735
143. K.B. Seaman W. Padgett J.W. Daly Forskolin: unique deterpene activator of adenylate cyclase in membranes and in intact cells Proc. Natl Acad. Sci. 78 1981 3367 3373 (USA)
144. J.J. Segura J.M. Guerrero R. Goberna J.R. Calvo Characterization of functional receptors for vasoactive intestinal peptide (VIP) in rat peritoneal macrophages Regul. Pept. 35 1991 133 143
145. F. Shanahan J.A. Denburg J. Fox J. Bienenstock D. Befus Mast cell heterogeneity: effects of neuroenteric peptides on histamine release J. Immunol. 135 1985 1331 1337
146. A. Shimatsu Y. Kato N. Matsushita H. Katakami N. Yanaihara H. Imura Effects of glucagon, neurotensin and vasoactive intestinal polypeptide on somatostatin release from perfused rat hypothalamus Endocrinology 110 1982 2113 2117
147. M.C. Sirianni B. Annibale F. Tagliaferri S. Fais S. De Luca F. Pallone G. Delle Fave F. Aiuti Modulation of human natural killer activity by vasoactive intestinal peptide (VIP) family. VIP, glucagon, and GHRF specifically inhibit NK activity Regul. Pept. 38 1992 79 87
148. S.P. Sreedharan D.R. Patel J.-X. Huang E.J. Goetzl Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor Biochem. Biophys. Res. Commun. 193 1993 546 553
149. A.M. Stanisz D. Befus J. Bienenstock Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferation by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen J. Immunol. 136 1986 152 156
150. A.M. Stanisz R. Scicchitano J. Bienenstock The role of vasoactive intestinal peptide and other neuropeptides in the regulation of the immune response in vitro and in vivo Ann. N.Y. Acad. Sci. 527 1988 478 485
151. R.H. Stead J. Bienenstock A.M. Stanisz Neuropeptide regulation of mucosal immunity Immunol. Rev. 100 1987 333 359
152. L. Sun D. Ganea Vasoactive intestinal peptide inhibits interleukin (IL)-2 and IL-4 production through different molecular mechanisms in T cells activated via the T cell receptor/CD3 complex J. Neuroimmunol. 48 1993 59 70
153. S.C. Tang H. Braunsteirner C.J. Wiedermann Regulation of human T lymphoblast growth by sensory neuropeptides: augmentation of cholecystokinin-induced inhibition of Molt-4 proliferation by somatostatin and vasoactive intestinal peptide in vitro Immunol. Lett. 34 1992 237 242
154. D.C. Thompson R.J. Altiere L. Diamond The effects of antagonists of vasoactive intestinal peptide on nonadrenergic noncholinergic inhibitory responses in feline airways Peptides 9 1988 443 447
155. R. Toni I. Kakucska S. Mosca P. Marrama R.M. Lechan Hypothyroidism increases vasoactive intestinal polypeptide (VIP) immuno-reactivity and gene expression in the rat hypothalamic paraventricular nucleus Endocrinology 131 1992 976 978
156. J.T. Turner D.B. Bylund Characterization of the vasoactive intestinal peptide receptor in rat submandibular gland: radioligand binding assay in membrane preparations J. Pharmacol. Exp. Ther. 242 1987 873 881
157. R. Uddman J. Alumets O. Densert R. Hakanson F. Sundler Occurrence and distribution of VIP nerves in the nasal mucosa and tracheobronchial wall Acta Otolaryngol 86 1978 443 448
158. R. Uddman F. Sundler VIP nerves in human upper respiratory tract Otorhinolaryngology 41 1979 221 226
159. B.J. Undem E.C. Dick C.K. Buckner Inhibition by vasoactive intestinal peptide of antigen-induced histamine release from guinea-pig minced lung Eur. J. Pharmacol. 88 1983 247 249
160. E.A.F. van Tol H.W. Verspaget B.E. Hansen C.B.H.W. Lamers Neuroenteric peptides affect natural killer activity by intestinal lamina propria mononuclear cells J. Neuroimmunol. 42 1993 139 146
161. E.A.F. van Tol H.W. Verspaget A.S. Pena J.B.M.J. Jansen N. Aparicio-Pages C.B.H.W. Lamers Modulatory effects of VIP and related peptides from the gastrointestinal tract on cell mediated cytotoxicity against tumour cells in vitro Immunol. Invest. 20 1991 257 267
162. W. Wan L. Janz C.Y. Vriend C.M. Sorensen A.H. Greenberg D.M. Nance Differential induction of c-fos immunoreactivity in hypothalamus and brain stem nuclei following central peripheral administration of endotoxin Brain Res. Bull. 32 1993 581 587
163. J.V. Weinstock A.M. Blum Detection of vasoactive intestinal peptide and localization of its mRNA within granulomas of murine schistosomiasis Cell. Immunol. 125 1990 291 300
164. J.V. Weinstock A.M. Blum S. Khetarpal Granulomas in murine Schistosomiasis mansoni contain vasoactive intestinal peptide-responsive lymphocytes Cell. Immunol. 134 1991 458 472
165. J.R. Westley A.I. Vinik T.M. O'Dorisio B. Glaser A. Fink A new syndrome of symptomatic cutaneous mastocytoma producing vasoactive intestinal polypeptide Gastroenterology 82 1982 963 967
166. P. Wiik Vasoactive intestinal peptide inhibits the respiratory burst in human monocytes by a cyclic AMP-mediated mechanism Regul. Pept. 25 1989 187 197
167. P. Wiik P.K. Opstad A. Boyum Binding of vasoactive intestinal polypeptide (VIP) by human blood monocytes: demonstration of specific binding sites Regul. Pept. 12 1985 145 153
168. Y. Yiangou N.D. Christofides M.A. Blank N. Yanaihara K. Tatemoto A.E. Bishop J.M. Polak S.R. Bloom Molecular forms in peptide histidine isoleucine-like immunoreactivity in the gastrointestinal tract. Nonequimolar levels of peptide histidine isoleucine and vasoactive intestinal peptide in the stomach explained by the presence of a big peptide histidine isoleucine-like molecule Gastroenterology 89 1985 516 524
169. Y. Yiangou R. Serrano J. Pena H. Festenstein Effects of prepro-vasoactive intestinal peptide-derived peptides on the murine immune response J. Neuroimmunol. 29 1990 65 72
170. A. Yuwiler Vasoactive intestinal peptide stimulation of pineal serotonin- N -acetyltransferase activity: General characteristics J. Neurochem. 41 1983 146 153
171. H.J. Zentel E. Weihe The neuro-B cell link of peptidergic innervation in the bursa Fabricii Brain Behav. Immun. 5 1991 132 147