Effect of bisphosphonates on the increase in bone resorption induced by a low calcium diet

Calcified Tissue International

Volumn 58, Issue 6, 1996, Pages 443-448

  Antic, V N ^a   Fleisch, H ^a   Muhlbauer R C ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Bisphosphonates; Bone resorption; Low calcium diet

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CLODRONIC ACID; IBANDRONIC ACID; PARATHYROID HORMONE; TETRACYCLINE; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM INTAKE; CONTROLLED STUDY; DIET RESTRICTION; DOSE RESPONSE; MALE; NONHUMAN; OSTEOLYSIS; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; THYROPARATHYROIDECTOMY; URINARY EXCRETION;

ALENDRONATE; ANIMALS; BONE RESORPTION; CALCIUM; CALCIUM, DIETARY; CLODRONIC ACID; DIPHOSPHONATES; DISEASE MODELS, ANIMAL; HOMEOSTASIS; MALE; RATS; RATS, WISTAR; TETRACYCLINE;

EID: 0029900461     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900073     Document Type: Article

References (24)

1. Fleisch H, Russell RGG, Francis MD (1969) Diphosphonates inhibit hydroxyapatite dissolution in vitro and bone resorption in tissue culture and in vivo. Science 165:1262-1264
2. Fleisch H (1995) Bisphosphonates in bone disease: from the laboratory to the patient, 2nd ed. The Parthenon Publishing Group Inc., London, New York
3. Kanis JA (1991) Drugs used for the treatment of Paget's disease. In: Kanis JA. Pathophysiology and treatment of Paget's disease of bone. Martin Dunitz Ltd, London, pp 159-216
4. Fleisch H (1991) Bisphosphonates. Pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease. Drugs 42:919-944
5. Watts NB, Harris ST, Genant HK, Wasnich RD, Miller PD, Jackson RD, Licata AA, Ross P, Woodson GC, Yanover MJ, Mysiw WJ, Kohse L, Rao MB, Steiger P, Richmond B, Chesnut CH III (1990) Intermittent cyclical etidronate treatment of postmenopausal osteoporosis. N Engl J Med 323:73-79
6. Adami S, Baroni MC, Broggini M, Carratelli L, Caruso I, Gnessi L, Laurenzi M, Lombardi A, Norbiato G, Ortolani S, Ricerca E, Romanini L, Subrizi S, Weinberg J, Yates AJ (1993) Treatment of postmenopausal osteoporosis with continuous daily oral alendronate in comparison with either placebo or intranasal salmon calcitonin. Osteoporosis Int (suppl 3):S21-27
7. Reid IR, Wattie DJ, Evans MC, Gamble GD, Stapleton JP, Cornish J (1994) Continuous therapy with pamidronate, a potent bisphosphonate, in postmenopausal osteoporosis. J Clin Endocrinol Metab 79:1595-1599
8. Chesnut CH, McClung MR, Ensrud KE, Bell NH, Genant HK, Harris ST, Singer FR, Stock JL, Yood RA, Delmas PD, Kher U, Pryor-Tillotson S, Santora AC (1995) Alendronate treatment of the postmenopausal osteoporotic woman: effect of multiple dosages on bone mass and bone remodeling. Am J Med 99:144-152
9. Liberman UA, Weiss SR, Bröll J, Minne HW, Quan H, Bell NH, Rodrigues-Portales J, Downs RW, Dequeker J, Favus M, Seeman E, Recker RR, Capizzi T, Santora AC, Lombardi A, Shah RV, Hirsch LJ, Karpf DB (1995) Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. N Engl J Med 333:1437-1443
10. Klein L, Jackman K (1976) Assay of bone resorption in vivo with 3H-tetracycline. Calcif Tissue Res 20:275-290
11. Klein L, Wong KM, Simmelink JW (1985) Biochemical and autoradiographic evaluation of bone turnover in prelabeled dogs and rabbits on normal and calcium-deficient diets. Bone 6:395-399
12. Mühlbauer RC, Fleisch H (1990) A method for continual monitoring of bone resorption in rats: evidence for a diurnal rhythm. Am J Physiol 258:R679-R689
13. Mühlbauer RC, Fleisch H (1995) The diurnal rhythm of bone resorption in the rat. Effect of feeding habits and pharmacological inhibitors. J Clin Invest 95:1933-1940
14. Trechsel U, Stutzer A, Fleisch H (1987) Hypercalcemia induced with an arotinoid in thyroparathyroidectomized rats. A new model to study bone resorption in vivo. J Clin Invest 80:1679-1686
15. Mühlbauer RC, Bauss F, Schenk R, Janner M, Bosies E, Strein K, Fleisch H (1991) BM 21.0955, a potent new bisphosphonate to inhibit bone resorption. J Bone Miner Res 6:1003-1011
16. Mühlbauer RC, Bonjour JP, Fleisch H (1977) Tubular localization of adaptation to dietary phosphate in rats. Am J Physiol 233:F342-F348
17. Wong KM, Singer L, Ophaug RH (1980) Metabolic aspects of bone resorption in calcium-deficient lactating rats. Calcif Tissue Int 32:213-219
18. Kalu DN, Hadji-Georgopoulos A, Sarr MG, Solomon BA, Foster GV (1974) The role of parathyroid hormone in the maintenance of plasma calcium levels in rats. Endocrinology 95:1156-1165
19. Haldimann B, Bonjour JP, Fleisch H (1977) Role of parathyroid hormone in regulation of main calcium fluxes in rats. Am J Physiol 232:E535-E541
20. Inomata N, Akiyama M, Kubota N, Jüppner H (1995) Characterization of a novel parathyroid hormone (PTH) receptor with specificity for the carboxyl-terminal region of PTH-(1-84). Endocrinology 136:4732-4740
21. Gasser AB, Morgan DB, Fleisch HA, Richelle LJ (1972) The influence of two diphosphonates on calcium metabolism in the rat. Clin Sci 43:31-45
22. Morgan DB, Gasser A, Largiadèr U, Jung A, Fleisch H (1975) Effects of a diphosphonate on calcium metabolism in calcium-deprived rats. Am J Physiol 228:1750-1756
23. Stutzer A, Fleisch H, Trechsel U (1988) Short- and long-term effects of a single dose of bisphosphonates on retinoid-induced bone resorption in thyroparathyroidectomized rats. Calcif Tissue Int 43:294-299
24. Adami S, Bolzicco GP, Rizzo A, Salvagno G, Bertoldo F, Rossini M, Suppi R, Lo Cascio V (1987) The use of dichloromethylene bisphosphonate and aminobutane bisphosphonate in hypercalcemia of malignancy. Bone Miner 2:395-404