Convenient one-pot synthesis of β-alkyl thio acid derivatives from thioacetates and the corresponding α,β-unsaturated compounds

Synthetic Communications

Volumn 26, Issue 11, 1996, Pages 2189-2196

  Lee, Dong Won ^a   Choi, Jaesung ^a   Yoon, Nung Min ^a  

^a Sogang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

SULFIDE; THIOL DERIVATIVE;

ARTICLE; CATALYSIS; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029899750     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003578     Document Type: Article

References (6)

1. Peach, M. E. Thiols as Nucleophiles. In The Chemistry of The Thiol Group; Patai, S., Ed. Wiley-Interscience: New York, 1974, Part 2, pp 721-784.
2. Hurd, C. D. and Gershbein, L. L. J. Org. Chem. 1947, 69, 2328.
3. Kuwajima, I., Murofushi, T., and Nakamura, E. Synthesis 1976, 602.
4. Taniguchi, Y., Maruo, M., Takaki, K., and Fujiwara, Y. Tetrahedron Lett. 1994, 35, 7789.
5. Choi, J. and Yoon, N. M. Synth. Commun. in press.
6. 3OH is an excellent reagent for the synthesis of phenyl sulfides from alkyl halides. However this system did not react with methyl crotonate under the standard conditions: Yoon, N. M., Choi, J., and Ahn, J. H. J. Org. Chem. 1994, 59, 3490.