The micronucleus test and NTP rodent carcinogens: Not so many false negatives

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 352, Issue 1-2, 1996, Pages 185-188

  Galloway, Sheila M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

BONE MARROW; CARCINOGEN TESTING; CYTOGENETICS; GENOTOXICITY; LABORATORY DIAGNOSIS; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REVIEW; RODENT;

RODENTIA;

EID: 0029898987     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(95)00225-1     Document Type: Article

References (5)

1. Albanese, R., E. Mirkova, D. Gatehouse and J. Ashby (1988) Species-specific response to the rodent carcinogens 1,2-dimethylhydrazine and 1,2-dibromo-chloropropane in rodent bone-marrow micronucleus assays, Mutagenesis, 3, 35-38.
2. Ashby, J. (1994) Benzyl acetate: from mutagenic carcinogen to non-mutagenic non-carcinogen in 7 years? Mutation Res., 306, 107-109.
3. Ashby, J and R.W. Tennant (1991) Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the US NTP, Mutation Res., 257, 229-306.
4. Shelby, M.D., G.L. Erexson, G.J. Hook and R.R. Tice (1993) Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Mol. Mutagen, 21, 160-179.
5. Tinwell, H. and J. Ashby (1994) Comparative activity of human carcinogens and NTP rodent carcinogens in the mouse bone marrow micronucleus assay. Environ. Health Perspect., 102, 758-762.