The effect of combination splenectomy and low-dose FK506 therapy on graft survival after liver allograft transplantation in rats

Transplantation

Volumn 61, Issue 10, 1996, Pages 1522-1525

  Kashu, Yasuaki ^a   Abe, Yasuhito ^a   Miyauchi, Katsutoshi ^a   Nakata, Tatsuhiro ^a   Watanabe, Yuji ^a   Sato, Motomichi ^a   Sato, Naoshi ^a   Kimura, Shigeru ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE TREATMENT; JAUNDICE; LIVER TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPLENECTOMY; TREATMENT OUTCOME; XENOTRANSPLANTATION;

ANIMALS; B-LYMPHOCYTES; BODY WEIGHT; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; GRAFT SURVIVAL; IMMUNOSUPPRESSION; ISOANTIBODIES; LIVER TRANSPLANTATION; MALE; RATS; RATS, INBRED ACI; RATS, INBRED LEW; SPLENECTOMY; TACROLIMUS;

EID: 0029898793     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199605270-00019     Document Type: Article

References (26)

1. Starzl T, Todo S, Fung J, Demetris A, Venkataramman R, Jain A. FK506 for liver, kidney, and pancreas transplantation. Lancet 1989; ii: 1000.
2. Todo S, Fung JJ, Starzl TE. Liver, kidney and thoracic organ transplantation under FK506. Ann Surg 1990; 212: 295.
3. Egawa H, Esquivel CO, So SK, Cox K. FK506 conversion therapy in pediatric liver transplantation. Transplantation 1994; 57: 1169.
4. Klintmalm G, Iwatsuki S, Starzl T. Nephrotoxicity of cyclosporin A in liver and kidney transplant patient. Lancet 1981; 2: 470.
5. MacCauley J, Fung JJ, Jain A, Todo S, Starzl TE. The effects of FK506 on renal function after liver transplantation. Transplant Proc 1990; 22: 17.
6. Vathsala A, Goto S, Yoshimura N, Stepkowski S, Chou TC, Kahan BD. The immunosuppressive antagonism of low doses of FK506 and cyclosporine. Transplantation 1991; 52: 121.
7. Tanabe M, Todo S, Murase N, Irish W, Miyazawa H, Fujisaki S, Starzl TE. Combined immunosuppressive therapy with low dose FK506 and antimetabolites in rat allogeneic heart transplantation. Transplantation 1994; 58: 23.
8. Candinas D, Achilleos O, Lee SJ, et al. Efficacy of leflunomide in combination with current immunosuppressive agents in rat cardiac allotransplantation. Transplant Proc 1994; 26: 3251.
9. Morikawa K, Oseko F, Morikawa S, Sawada M. Immunosuppressive activity of fosfomycin on human T-lymphocyte function in vitro. Antimicrob Agents Chemother 1993; 37: 2684.
10. Chavin KD, Qin L, Woodward JE, Lin J, Bromberg JS. Anti-CD2 monoclonal antibodies synergize with FK506 but not with cyclosporine or rapamycin to induce tolerance. Transplantation 1994; 57: 736.
11. Latinne D, Soares M, Havaux X, Cormont F, Lesnikoski B, Bach FH, Bazin H. Depletion of IgM xenoreactive natural antibodies by injection of anti-mu monoclonal antibodies. Immunol Rev 1994; 141: 95.
12. Leventhal J, Flores H, Gruber S, Figueroa J, Platt J, Manivel J, Bach F, Matas A, Bolman R. Evidence that 15-deoxyspergualin inhibits natural antibody production but fails to prevent hyperacute rejection in a discordant xenograft model. Transplantation 1992; 54: 26.
13. Valdivia L, Monden M, Gotoh M, Nakano Y, Tono T, Mori T. Evidence that deoxyspergualin prevents sensitization and first-set cardiac xenograft rejection in rats by suppression of antibody formation. Transplantation 1990; 50: 132.
14. Murase N, Starzl TE, Demetris AJ, Valdivia L, Tanabe M, Cramer D, Makowka L. Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. Transplantation 1993; 55: 701.
15. Latinne D, Bazin H. Removal of circulating IgM from xenograft recipients. Transplant Proc 1994; 26: 1363.
16. Yamaguchi Y, Halperin EC, Harland RC, Wyble C, Bollinger RR. Significant prolongation of hamster liver transplant survival in Lewis rats by total-lymphoid irradiation, cyclosporine, and splenectomy. Transplantation 1990; 49: 13.
17. Langer A, Valdivia LA, Murase N, Woo J, Celli S, Fung JJ, Starzl TE, Demetris AJ. Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection: marked stimulation of IgM++bright/IgD+dull splenic B cells. Am J Pathol 1993; 143: 85.
18. Kamada N, Calne R. Orthotopic liver transplantation in the rat. Transplantation 1979; 28: 47.
19. Renard TH, Andrews WS. An approach to ABO-incompatible liver transplantation in children. Transplantation 1992; 53: 116.
20. Tsugita M, Valdivia LA, Woo J, et al. The effect of splenectomy on cardiac and liver xenografts in the nude rat. Transplant Proc 1994; 26: 1210.
21. Baldwin W, Rhoton K, Sanfilippo F. IgM and IgG alloantibody production by splenocytes and deposition in rat renal allografts are decreased by donor-specific blood transfusion. Transplantation 1991; 51: 481.
22. Sun J, McCaughan GW, Matsumoto Y, Sheil AG, Gallagher ND, Bishop GA. Tolerance to rat liver allografts: I. Differences between tolerance and rejection are more marked in the B cell compared with the T cell or cytokine response. Transplantation 1994; 57: 1349.
23. Nakano Y, Monden M, Valdivia LA, Gotoh M, Tono T, Mori T. Permanent acceptance of liver allografts by intraportal injection of donor spleen cells in rats. Surgery 1992; 111: 668.
24. Yamaoka K, Kim KM, Ishigami T, et al. Cyclosporin A and FK506 block the negative signaling mediated by surface IgM cross-linking in normal human mature B cells. Immunol Lett 1993; 36: 203.
25. Boussiotis VA, Nadler LM, Strominger JL, Goldfeld AE. Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. Proc Natl Acad Sci USA 1994; 91: 7007.
26. Goldfeld AE, Flemington EK, Boussiotis VA, et al. Transcription of the tumor necrosis factor alpha gene is rapidly induced by antiimmunoglobulin and blocked by cyclosporin A and FK506 in human B cells. Proc Natl Acad Sci USA 1992; 89: 12198.