메뉴 건너뛰기




Volumn 26, Issue 5, 1996, Pages 411-417

The antifibrinolytic effect of lipoprotein(a) in heterozygous subjects is modulated by the relative concentration of each of the apolipoprotein(a) isoforms and their affinity for fibrin

Author keywords

Apo(a); apolipoprotein(a); atherosclerosis; lipoprotein(a); Lp(a); plasminogen; thr ombosis

Indexed keywords

APOLIPOPROTEIN A; LIPOPROTEIN A; PLASMINOGEN;

EID: 0029898657     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.1996.156288.x     Document Type: Article
Times cited : (40)

References (40)
  • 1
    • 0024963945 scopus 로고
    • Thrombogenesis linked to atherogenesis at last?
    • Scott J. Thrombogenesis linked to atherogenesis at last? Nature 1989;341:22-3.
    • (1989) Nature , vol.341 , pp. 22-23
    • Scott, J.1
  • 2
    • 0022515518 scopus 로고
    • Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography
    • Dahlen GH, Guyton JR, Arrar M, Farmer JA, Kautz JA, Gotto AM. Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography. Circulation 1986;74:758-65.
    • (1986) Circulation , vol.74 , pp. 758-765
    • Dahlen, G.H.1    Guyton, J.R.2    Arrar, M.3    Farmer, J.A.4    Kautz, J.A.5    Gotto, A.M.6
  • 3
    • 0023636242 scopus 로고
    • cDNA sequence of human apolipoprotein(a) is homologous to plasminogen
    • McLean JW, Tomlinson JE, Kuang WJ et al. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature 1987;330:132-7.
    • (1987) Nature , vol.330 , pp. 132-137
    • McLean, J.W.1    Tomlinson, J.E.2    Kuang, W.J.3
  • 4
    • 0010965565 scopus 로고
    • Partial amino acid sequence of apolipoprotein(a) shows that is homologous to plasminogen
    • Eaton DL, Fless GM, Kohn WJ et al. Partial amino acid sequence of apolipoprotein(a) shows that is homologous to plasminogen. Proc Natl Acad Sci USA. 1987;84:3224-8.
    • (1987) Proc Natl Acad Sci USA. , vol.84 , pp. 3224-3228
    • Eaton, D.L.1    Fless, G.M.2    Kohn, W.J.3
  • 5
    • 0027179248 scopus 로고
    • Molecular definition of the extreme size polymorphism in apolipoprotein(a)
    • Lackner C, Cohen JC, Hobbs HH. Molecular definition of the extreme size polymorphism in apolipoprotein(a). Hum Mol Genet 1993;2:933-40.
    • (1993) Hum Mol Genet , vol.2 , pp. 933-940
    • Lackner, C.1    Cohen, J.C.2    Hobbs, H.H.3
  • 6
    • 0027237890 scopus 로고
    • Identification of 34 apolipoprotein(a) isoforms: Differential expression of apolipoprotein(a) alleles between american blacks and whites
    • Marcovina SM, Zhang ZH, Gaur VP, Albers JJ. Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between american blacks and whites. Biochem Biophys Res Comm 1993;191:1192-6.
    • (1993) Biochem Biophys Res Comm , vol.191 , pp. 1192-1196
    • Marcovina, S.M.1    Zhang, Z.H.2    Gaur, V.P.3    Albers, J.J.4
  • 7
    • 0025938419 scopus 로고
    • Expressed hypervariable polymorphism of apolipoprotein(a)
    • Llyas Kamboch M, Ferrell RE, Kottke BA. Expressed hypervariable polymorphism of apolipoprotein(a). Am J Hum Genet 1991;49:1063-74.
    • (1991) Am J Hum Genet , vol.49 , pp. 1063-1074
    • Llyas Kamboch, M.1    Ferrell, R.E.2    Kottke, B.A.3
  • 8
    • 0020490296 scopus 로고
    • Location of the intermediate and high affinity ω-aminocarboxylic acid-binding sites in human plasminogen
    • Vali Z, Patthy L. Location of the intermediate and high affinity ω-aminocarboxylic acid-binding sites in human plasminogen. J Biol Chem 1982;257:2104-10.
    • (1982) J Biol Chem , vol.257 , pp. 2104-2110
    • Vali, Z.1    Patthy, L.2
  • 9
    • 0025764362 scopus 로고
    • Lipoprotein(a) impairs generation of plasmin by fibrin bound tissue-type plasminogen activator
    • Rouy D, Grailhe P, Nigon F, Chapman MJ, Anglés-Cano E. Lipoprotein(a) impairs generation of plasmin by fibrin bound tissue-type plasminogen activator. Arterioscler Thromb 1991; 11:629-38.
    • (1991) Arterioscler Thromb , vol.11 , pp. 629-638
    • Rouy, D.1    Grailhe, P.2    Nigon, F.3    Chapman, M.J.4    Anglés-Cano, E.5
  • 10
    • 0012600414 scopus 로고
    • Plasmin catalyses binding of lipoprotein(a) to immobilized fibrinogen and fibrin
    • Harpel PC, Gordon BR, Parker TS. Plasmin catalyses binding of lipoprotein(a) to immobilized fibrinogen and fibrin. Proc Natl Acad Sci USA 1989;86:3847-51.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3847-3851
    • Harpel, P.C.1    Gordon, B.R.2    Parker, T.S.3
  • 12
    • 0024539832 scopus 로고
    • Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis
    • Hajjar KA, Gavish D, Breslow JL, Nachman RL. Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis. Nature 1989;339:303-5.
    • (1989) Nature , vol.339 , pp. 303-305
    • Hajjar, K.A.1    Gavish, D.2    Breslow, J.L.3    Nachman, R.L.4
  • 13
    • 0024554547 scopus 로고
    • A potential basis for the thrombotic risks associated with lipoprotein(a)
    • Miles LA, Fless GM, Levin EG, Scanu AM, Plow EF. A potential basis for the thrombotic risks associated with lipoprotein(a). Nature 1989;339:301-3.
    • (1989) Nature , vol.339 , pp. 301-303
    • Miles, L.A.1    Fless, G.M.2    Levin, E.G.3    Scanu, A.M.4    Plow, E.F.5
  • 14
    • 0027288033 scopus 로고
    • Comparison of ligand-binding sites of modeled apo(a) kringle-like sequences in human lipoprotein(a)
    • Guevara J, Jan YJ, Knapp R, Tulinsky A, Morrisett JD. Comparison of ligand-binding sites of modeled apo(a) kringle-like sequences in human lipoprotein(a). Arterioscler Thromb 1993;13:758-70.
    • (1993) Arterioscler Thromb , vol.13 , pp. 758-770
    • Guevara, J.1    Jan, Y.J.2    Knapp, R.3    Tulinsky, A.4    Morrisett, J.D.5
  • 15
    • 0027446093 scopus 로고
    • Rhesus monkey lipoprotein(a) binds to lysine sepharose and U937 monocytoid cells less efficiently than in human lipoprotein(a)
    • Scanu AM, Miles LA, Fless GM et al. Rhesus monkey lipoprotein(a) binds to lysine sepharose and U937 monocytoid cells less efficiently than in human lipoprotein(a). J Clin Invest 1993; 91:283-91.
    • (1993) J Clin Invest , vol.91 , pp. 283-291
    • Scanu, A.M.1    Miles, L.A.2    Fless, G.M.3
  • 16
    • 0023393811 scopus 로고
    • Lp(a) glycoprotein phenotypes: Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma
    • Utermann G, Menzel H, Kraft H, Duba H, Kemmler H, Seitz C. Lp(a) glycoprotein phenotypes: inheritance and relation to Lp(a)-lipoprotein concentrations in plasma. J Clin Invest 1987; 80:458-65.
    • (1987) J Clin Invest , vol.80 , pp. 458-465
    • Utermann, G.1    Menzel, H.2    Kraft, H.3    Duba, H.4    Kemmler, H.5    Seitz, C.6
  • 17
    • 0027293533 scopus 로고
    • Does apolipoprotein (a) heterogeneity influence lipoprotein(a) effects on fibrinolysis?
    • Hervio L, Chapman MJ, Thillet J, Loyau S, Anglés-Cano E: Does apolipoprotein (a) heterogeneity influence lipoprotein(a) effects on fibrinolysis? Blood 1993;82:392-7.
    • (1993) Blood , vol.82 , pp. 392-397
    • Hervio, L.1    Chapman, M.J.2    Thillet, J.3    Loyau, S.4    Anglés-Cano, E.5
  • 18
    • 0026667073 scopus 로고
    • Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations
    • Boerwinkle E, Leffert CC, Lin J, Lackner C, Chiesa G, Hobbs HH. Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. J Clin Invest 1992;90:52-9.
    • (1992) J Clin Invest , vol.90 , pp. 52-59
    • Boerwinkle, E.1    Leffert, C.C.2    Lin, J.3    Lackner, C.4    Chiesa, G.5    Hobbs, H.H.6
  • 19
    • 0026509691 scopus 로고
    • Apolipoprotein(a) alleles determine lipoprotein(a) particle density and concentration in plasma
    • Kraft HG, Sandholzer C, Menzel HG, Utermann G. Apolipoprotein(a) alleles determine lipoprotein(a) particle density and concentration in plasma. Arterioscler Thromb 1992;12:302-6.
    • (1992) Arterioscler Thromb , vol.12 , pp. 302-306
    • Kraft, H.G.1    Sandholzer, C.2    Menzel, H.G.3    Utermann, G.4
  • 20
    • 0021188563 scopus 로고
    • Heterogeneity of human plasma lipoprotein(a). Isolation and characterization of the lipoprotein subspecies and their apoproteins
    • Fless GM, Rolih C, Scanu AM. Heterogeneity of human plasma lipoprotein(a). Isolation and characterization of the lipoprotein subspecies and their apoproteins. J Biol Chem 1984;259:11470-8.
    • (1984) J Biol Chem , vol.259 , pp. 11470-11478
    • Fless, G.M.1    Rolih, C.2    Scanu, A.M.3
  • 21
    • 0023388743 scopus 로고
    • Enzymatically induced alterations in the structure of rat serum lipoproteins
    • Swaney JB, Orishimo M, Girard A: Enzymatically induced alterations in the structure of rat serum lipoproteins. J Lipid Res 1987;28:982-92.
    • (1987) J Lipid Res , vol.28 , pp. 982-992
    • Swaney, J.B.1    Orishimo, M.2    Girard, A.3
  • 22
    • 0021678736 scopus 로고
    • Electroblotting of multiple gels: A single apparatus without buffer tank for rapid transfer of protein from polyacrylamide to nitrocellulose
    • Khyse-Andersen J. Electroblotting of multiple gels: a single apparatus without buffer tank for rapid transfer of protein from polyacrylamide to nitrocellulose. J Biochem Biophys Methods 1984;10:203-9.
    • (1984) J Biochem Biophys Methods , vol.10 , pp. 203-209
    • Khyse-Andersen, J.1
  • 23
    • 0025718644 scopus 로고
    • Characterization of the binding of plasminogen to fibrin surfaces: The role of carboxy-terminal lysines
    • Fleury V, Anglés-Cano E. Characterization of the binding of plasminogen to fibrin surfaces: the role of carboxy-terminal lysines. Biochemistry 1991;30:7630-8.
    • (1991) Biochemistry , vol.30 , pp. 7630-7638
    • Fleury, V.1    Anglés-Cano, E.2
  • 24
    • 0001408345 scopus 로고
    • The preparation and some properties of fibrinogen precipitated from human plasma by glycine
    • Kazal LA, Amsel S, Miller OP, Tocantins LM. The preparation and some properties of fibrinogen precipitated from human plasma by glycine. Proc Soc Exp Biol Med 1963;113:989-94.
    • (1963) Proc Soc Exp Biol Med , vol.113 , pp. 989-994
    • Kazal, L.A.1    Amsel, S.2    Miller, O.P.3    Tocantins, L.M.4
  • 26
    • 0026723854 scopus 로고
    • Apolipoprotein(a) and plasminogen interactions with fibrin: A study with recombinant apolipoprotein(a) and isolated plasminogen fragments
    • Rouy D, Koschinsky ML, Fleury V, Chapman MJ, Anglés-Cano E. Apolipoprotein(a) and plasminogen interactions with fibrin: a study with recombinant apolipoprotein(a) and isolated plasminogen fragments. Biochemistry 1992;31:6333-9.
    • (1992) Biochemistry , vol.31 , pp. 6333-6339
    • Rouy, D.1    Koschinsky, M.L.2    Fleury, V.3    Chapman, M.J.4    Anglés-Cano, E.5
  • 27
    • 9344264752 scopus 로고
    • A simplification of the protein assay of Lowry et al. which is more generally applicable
    • Petersons GL. A simplification of the protein assay of Lowry et al. which is more generally applicable. Anal Biochem 1977;15: 45-52.
    • (1977) Anal Biochem , vol.15 , pp. 45-52
    • Petersons, G.L.1
  • 28
    • 0013895324 scopus 로고
    • Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies
    • Laurell CB. Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 1966;15:45-52.
    • (1966) Anal Biochem , vol.15 , pp. 45-52
    • Laurell, C.B.1
  • 29
    • 0026666728 scopus 로고
    • Serum lipoprotein(a) levels in racially different populations
    • Cobbaert C, Kesteloot H. Serum lipoprotein(a) levels in racially different populations. Am J Epidemiol 1992;136:441-9.
    • (1992) Am J Epidemiol , vol.136 , pp. 441-449
    • Cobbaert, C.1    Kesteloot, H.2
  • 30
    • 0024362630 scopus 로고
    • The mysteries of lipoprotem(a)
    • Utermann G. The mysteries of lipoprotem(a). Science 1989;246: 904-10.
    • (1989) Science , vol.246 , pp. 904-910
    • Utermann, G.1
  • 31
    • 0026560389 scopus 로고
    • Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: Evidence for the role of the apo(a) gene in coronary heart disease
    • Sandholzer CH, Boerwinkle E, Saha N, Tong MC, Utermann G. Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease. J Clin Invest 1992;89:1040-6.
    • (1992) J Clin Invest , vol.89 , pp. 1040-1046
    • Sandholzer, C.H.1    Boerwinkle, E.2    Saha, N.3    Tong, M.C.4    Utermann, G.5
  • 32
    • 0026700306 scopus 로고
    • Apo(a) isoforms predict risk for coronary heart disease. A study of six populations
    • Sandholzer CH, Saha N, Kark JD et al. Apo(a) isoforms predict risk for coronary heart disease. A study of six populations. Arterioscler Thromb 1992;12:1214-26.
    • (1992) Arterioscler Thromb , vol.12 , pp. 1214-1226
    • Sandholzer, C.H.1    Saha, N.2    Kark, J.D.3
  • 33
    • 0026631199 scopus 로고
    • Significant association between low-molecular-weight apolipoprotein(a) isoforms and intermittent claudication
    • Mölgaard J, Klausen IC, Lassvik C, Faergeman O, Gerdes LU. Olsson AG. Significant association between low-molecular-weight apolipoprotein(a) isoforms and intermittent claudication. Arterioscler Thomb 1992;12:895-901.
    • (1992) Arterioscler Thomb , vol.12 , pp. 895-901
    • Mölgaard, J.1    Klausen, I.C.2    Lassvik, C.3    Faergeman, O.4    Gerdes, L.U.5    Olsson, A.G.6
  • 34
    • 0027471324 scopus 로고
    • Plasma Lp(a), apolipoprotein(a) isoforms and acute myocardial infarction in men and women: A case-control study in the Jerusalem population
    • Kark JD, Sandholzer C, Friedlander Y, Utermann G. Plasma Lp(a), apolipoprotein(a) isoforms and acute myocardial infarction in men and women: a case-control study in the Jerusalem population. Atherosclerosis 1993;139-151.
    • (1993) Atherosclerosis , pp. 139-151
    • Kark, J.D.1    Sandholzer, C.2    Friedlander, Y.3    Utermann, G.4
  • 35
    • 0023940579 scopus 로고
    • Apolipoproteins (a), AI and B and parental history in man with early onset ischaemic heart disease
    • Durrington PN, Ishola M, Hunt L, Arrol S. Apolipoproteins (a), AI and B and parental history in man with early onset ischaemic heart disease. Lancet 1988;1:1070-3.
    • (1988) Lancet , vol.1 , pp. 1070-1073
    • Durrington, P.N.1    Ishola, M.2    Hunt, L.3    Arrol, S.4
  • 36
    • 0024557798 scopus 로고
    • Evidence for increased levels of plasminogen activator inhibitor and tissue plasminogen activator in plasma of patients with angiographically verified coronary artery disease
    • Oloffson BO, Dahlen G, Bilsson TK. Evidence for increased levels of plasminogen activator inhibitor and tissue plasminogen activator in plasma of patients with angiographically verified coronary artery disease. Eur J Heart 1989;1:77-82.
    • (1989) Eur J Heart , vol.1 , pp. 77-82
    • Oloffson, B.O.1    Dahlen, G.2    Bilsson, T.K.3
  • 37
    • 0026592584 scopus 로고
    • Lack of association between Lp(a) concentrations and coronary heart disease mortality in diabetes: The Wisconsin epidemiologic Study of Diabetic Retinopathy
    • Haffner SM, Moss SE, Klein BE, Klein R. Lack of association between Lp(a) concentrations and coronary heart disease mortality in diabetes: the Wisconsin epidemiologic Study of Diabetic Retinopathy. Metabolism 1992;41:194-7.
    • (1992) Metabolism , vol.41 , pp. 194-197
    • Haffner, S.M.1    Moss, S.E.2    Klein, B.E.3    Klein, R.4
  • 38
    • 0025769197 scopus 로고
    • Lipoprotein (a) and coronary heart disease risk: A nested case-control study of the Helsinki Heart Study participants
    • Jauhiainen M, Koskinen P, Ehnholm C et al. Lipoprotein (a) and coronary heart disease risk: a nested case-control study of the Helsinki Heart Study participants. Atherosclerosis 1991;89: 59-67.
    • (1991) Atherosclerosis , vol.89 , pp. 59-67
    • Jauhiainen, M.1    Koskinen, P.2    Ehnholm, C.3
  • 39
    • 0027366185 scopus 로고
    • A prospective study of lipoprotein(a) and the risk of myocardial infarction
    • Ridker PM, Hennekens CH, Stamper MJ. A prospective study of lipoprotein(a) and the risk of myocardial infarction. JAMA 1993;270:2195-9.
    • (1993) JAMA , vol.270 , pp. 2195-2199
    • Ridker, P.M.1    Hennekens, C.H.2    Stamper, M.J.3
  • 40
    • 0028786755 scopus 로고
    • Multiple binding with identical linkage: A mecanism that explains the effect of lipoprotein(a) on fibrinolysis
    • Hervio L, Durlach V, Girard-Globa A, Anglés-Cano E. Multiple binding with identical linkage: a mecanism that explains the effect of lipoprotein(a) on fibrinolysis. Biochemistry 1995;34: 595-606.
    • (1995) Biochemistry , vol.34 , pp. 595-606
    • Hervio, L.1    Durlach, V.2    Girard-Globa, A.3    Anglés-Cano, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.