Topically applied recombinant tissue plasminogen activator for the treatment of venous ulcers: Preliminary report

Dermatologic Surgery

Volumn 22, Issue 7, 1996, Pages 643-644

  Falanga, Vincent ^a,b,d   Carson, Polly ^a   Greenberg, Adam ^a   Hasan, Anthony ^a   Nichols, Edward ^c   Mcpherson, John ^c  

^a UNIVERSITY OF MIAMI   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c GENZYME CORPORATION   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; FIBRIN;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EPITHELIZATION; FIBRIN DEPOSITION; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION; ULCER; ULCER HEALING;

EID: 0029898529     PISSN: 10760512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1524-4725.1996.tb00611.x     Document Type: Article

References (8)

1. Falanga V. Venous ulceration. J Dermatol Surg Oncol 1993;19: 764-71.
2. Falanga V, Eaglstein WH. The trap hypothesis of venous ulceration. Lancet 1993;341:1006-8.
3. Falanga V, Kirsner RS, Katz MH, Gould E, Eaglstein WH, McFalls. Pericapillary Fibrin Cuffs in venous ulceration. J Dermatol Surg Oncol 1992;18:409-14.
4. R) in acute myocardial infarction. J Am Coll Cardiol 1987;9:1205-13.
5. Falanga V, Kruskal JB, Franks JJ. Fibrin and fibrinogen-related antigens in patients with venous disease and venous ulceration. Arch Dermatol 1991;127:75-8.
6. Browse NL, Burnand KG. The cause of venous ulceration. Lancet 1982;2:243-5.
7. Falanga V, Grinnell F, Gilchrest B, Maddox YT, Moshell A. Experimental approaches to chronic wounds. Wound Rep Reg 1995; 3:132-40.
8. Higley HR, Ksander GA, Gerhardt CO, Falanga V. Extravasation of macromolecules and possible trapping of TGF-beta in venous ulceration. Br J Dermatol 1995;132:79-85.