Functional identification of genes up- and down-regulated by glucocorticoids in AtT-20 pituitary cells using an enhancer trap

Endocrinology

Volumn 137, Issue 7, 1996, Pages 2758-2765

  Harrison, Robert W ^a   Miller, Janice C ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; GLUCOCORTICOID RECEPTOR;

ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; DNA STRUCTURE; ENHANCER REGION; HORMONAL REGULATION; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; TRANSGENE;

EID: 0029898497     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.7.8770895     Document Type: Article

References (55)

1. Arnold C, Hodgson IJ 1991 Vectorette PCR: a novel approach to genomic walking. PCR Methods Appl 1:39-42
2. Atkinson MJ, Freeman MW, Kronenberg HM 1990 Thymosin beta 4 is expressed in ROS 17/2.8 osteosarcoma cells in a regulated manner. Mol Endocrinol 4:69-74
3. Benjannet S, Rondeau N, Day R, Chretien M, Seidah NG 1991 PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. Proc Natl Acad Sci USA 88:3564-3568
4. Baughman G, Harrigan MT, Campbell NF, Nurrish SJ, Bourgeois S 1991 Genes newly identified as regulated by glucocorticoids in murine thymocytes. Mol Endocrinol 5:637-644
5. Budarf ML, Herbert E 1982 Effect of tunicamycin on the synthesis, processing, and secretion of pro-opiomelanocortin peptides in mouse pituitary cells. J Biol Chem 257:10128-10135
6. Bhat K, McBurney MW, Hamada H 1988 Functional cloning of mouse chromosomal loci specifically active in embryonal carcinoma stem cells. Mol Cell Biol 8:3251-3259
7. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
8. Cohen JJ 1992 Glucocorticoid-induced apoptosis in the thymus. Semin Immunol 4:363-369
9. Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR 1990 Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249:1266-1272
10. Feinberg AP, Vogelstein B 1983 A technique for radiolabeling DNA restriction endonuclease restriction fragments to high specific activity. Anal Biochem 132:6-13
11. Fickel J, Savoly S, Vogel U, Furkert J, Melzig M 1994 The proopiomelanocortin (POMC) gene expression of AtT20 mouse pituitary cells is dependent on cell culture conditions. Cell Mol Biol 40:201-209
12. Friedrich G, Soriano P 1991 Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5:1513-1523
13. Gametchu B, Harrison RW 1984 Characterization of a monoclonal antibody to the rat liver glucocorticoid receptor. Endocrinology 114:274-279
14. Garroway NW, Orth DN, Harrison RW 1976 Binding of cytosol receptor-glucocorticoid complexes by isolated nuclei of glucocorticoid-responsive and nonresponsive cultured cells. Endocrinology 98:1092-100
15. Hamada H 1986 Random isolation of gene activator elements from the human genome. Mol Cell Biol 6:4185-4194
16. Hamada H 1986 Activation of an enhancerless gene by chromosomal integration. Mol Cell Biol 6:4179-4184
17. Haralson MA, Fairfield SJ, Nicholson WE, Harrison RW, Orth DN 1979 Cell-free synthesis of mouse corticotropin. Evidence for two high molecular weight gene products. J Biol Chem 254:2172-2175
18. Harrison RW, Woodward C, Thompson E 1983 Titratable effects of p-chloromercuriphenyl sulfonate, a thiol-attacking reagent, on glucocorticoid receptor binding. Biochim Biophys Acta 759:1-6
19. Harrison RW, Miyabe S 1981 Steroid structure and nuclear translocation of glucocorticoid receptors in intact AtT-20 mouse pituitary tumor cells. J Steroid Biochem 15:393-396
20. Harrison RW, Lippman SS, Hendry WJ, Chien MC 1990 Isolation of a genomic sublibrary enriched for glucocorticoid-regulated genes. DNA Cell Biol 9:95-102
21. Harrison RW, Yeakley J 1979 Corticosterone binding in AtT-20 pituitary tumor cell cytosol: evidence for one class of binding site for both natural and synthetic glucocorticoids. Biochim Biophys Acta 583:360-369
22. Hawkins JD 1988 A survey on intron and exon lengths. Nucleic Acids Res 16:9893-9908
23. Hendry WJ, Hakkak R, Harrison RW 1993 An analysis of autologous glucocorticoid receptor protein regulation in AtT-20 cells also reveals differential specificity of the BuGR2 monoclonal antibody. Biochim Biophys Acta 1178:176-188
24. Howard K, Jaglarz M, Zhang N, Shah J, Warrior R 1993 Migration of Drosophila germ cells: analysis using enhancer trap lines. Development [Suppl] 213-218
25. Jones DH, Winistorfer SC 1993 Genome walking with 2- to 4-kb steps using panhandle PCR. PCR Methods Appl 2:197-203
26. Karin M, Yang-Yen HF, Chambard JC, Deng T, Saatcioglu F 1993 Various modes of gene regulation by nuclear receptors for steroid and thyroid hormones. Eur J Clin Pharmacol 45:S9-S15
27. Korn R, Schoor M, Neuhaus H, Henseling U, Soininen R, Zachgo J, Gossler A 1992 Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes. Mech Dev 39:95-109
28. LaPointe MC, Chang CH, Vedeckis WV 1986 Structure of the mouse glucocorticoid receptor: rapid analysis by size-exclusion high-performance liquid chromatography. Biochemistry 25:2094-2101
29. Lippman SS, Detection of glucocorticoid-regulated genes using an "enhancer-trap" plasmid. 70th Annual Meeting of The Endocrine Society, Washington DC, 1988 (Abstract 939)
30. Lupton SD, Brunton LL, Kalberg VA, Overell RW 1991 Dominant positive and negative selection using a hygromycin phosphotransferase-thymidine kinase fusion gene. Mol Cell Biol 11:3374-3378
31. Macleod D, Lovell-Badge R, Jones S, Jackson I 1990 A promoter trap in embryonic stem (ES) cells selects for integration of DNA into CpG islands. Nucleic Acids Res 19:17-23
32. Miyabe S, Harrison RW 1983 In vivo activation and nuclear binding of the AtT-20 mouse pituitary tumor cell glucocorticoid receptor. Endocrinology 112:2174-2180
33. Munck A, Naray-Fejes-Toth A 1992 The ups and downs of glucocorticoid physiology. Permissive and suppressive effects revisited. Mol Cell Endocrinol 90:C1-C4
34. Nakai Y, Usui T, Tsukada T, Takahashi H, Fukata J, Fukushima M, Senoo K Imura H 1991 Molecular mechanisms of glucocorticoid inhibition of human proopiomelanocortin gene transcription. J Steroid Biochem Mol Biol 40:301-306
35. Niwa H, Araki K, Kimura S, Taniguchi SI, Wakasugi S, Yamamura KI 1992 An efficient gene-trap method using poly A trap vectors and characterization of gene-trap events. J Biochem 113:343-349
36. O'Banion MK, Young DA, Bonn MC 1994 Corticosterone-responsive mRNAs in primary rat astrocytes. Mol Brain Res 22:57-68
37. Oikarinen A 1992 Dermal connective tissue modulated by pharmacologic agents. Int J Dermatol 31:149-156
38. Reed KC, Mann DA 1985 Rapid transfer of DNA from agarose gels to nylon membranes. Nucleic Acids Res 13:7207-7221
39. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning-A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor
40. Sandford RN, Elgar GS 1992 A novel method for rapid genomic walking using lambda vectors. Nucleic Acids Res 20:4665-4666
41. Sarkar GS, Turner RT, Bolander ME 1993 Restriction-site PCR: a direct method of unknown sequence retrieval adjacent to a known locus by using universal primers. PCR Methods Appl 2:318-322
42. Screaton GR, Bangham CR, Bell JI 1993 Direct sequencing of single primer PCR products: a rapid method to achieve short chromosomal walks. Nucleic Acids Res 21:2263-2264
43. Simons SS Jr, Oshima H, Szapary D 1992 Higher levels of control: modulation of steroid hormone-regulated gene transcription. Mol Endocrinol 6:995-1002
44. Staveley BE, Hodgetts RB, O'Keefe SL, Bell JB 1994 Targeting of an enhancer trap to vestigial. Dev Biol 165:290-293
45. Smith D, Wohlgemuth J, Calvi BR, Franklin I, Gelbart WM 1993 Hobo enhancer trapping mutagenesis in Drosophila reveals an insertion specificity different from P elements. Genetics 135:1063-1076
46. Tam WW, Andreasson KI, Loh YP 1993 The amino-terminal sequence of pro-opiomelanocortin directs intracellular targeting to the regulated secretory pathway. Eur J Cell Biol 62:294-306
47. Thakore JH, Dinan TG 1994 Growth hormone secretion: the role of glucocorticoids. Life Sci 55:1083-1099
48. Therrien M, Drouin J 1991 Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements. Mol Cell Biol 11:3492-3503
49. Thomas PS 1980 Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci USA 77:5201-5205
50. Truss M, Beato M 1993 Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocr Rev 14:459-479
51. Wahli W, Martinez E 1991 Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression. FASEB J 5:2243-2249
52. Watanabe H, Orth DN, Toft DO 1973 Glucocorticoid receptors in pituitary tumor cells. I. Cytosol receptors. J Biol Chem 248:7625-7630
53. Watanabe H, Orth DN, Toft DO 1974 Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding. Biochemistry 13: 332-337
54. Yeakley JM, Balasubramanian K, Harrison RW 1980 Comparison of glucocorticoid-receptor binding kinetics with predictions from a biomolecular model. J Biol Chem 255:4182-4188
55. Young DA 1984 Advantages of separations on "giant" two-dimensional gels for detection of physiologically relevant changes in the expression of protein gene-products. Clin Chem 30:2104-2108