A research shortcut from a common cold virus to human cancer

Cancer

Volumn 78, Issue 3, 1996, Pages 558-565

  Harlow, Ed ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

CANCER RESEARCH; CELL CYCLE; GLIOBLASTOMA; HUMAN; HUMAN RHINOVIRUS; MALIGNANT NEOPLASTIC DISEASE; MEDICAL RESEARCH; PRIORITY JOURNAL; RETINOBLASTOMA; REVIEW; TUMOR SUPPRESSOR GENE; VIRUS INFECTION;

ADENOVIRIDAE; ADENOVIRUS INFECTIONS, HUMAN; ANIMALS; CELL CYCLE; GENES, RETINOBLASTOMA; HUMANS; MUTATION; NEOPLASM PROTEINS; NEOPLASMS; TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 0029898213     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19960801)78:3<558::AID-CNCR26>3.0.CO;2-X     Document Type: Review

References (34)

1. Nevins JR: E2F: A link between the Rb Tumor suppressor protein and viral oncoproteins. Science 1992; 258:424-429.
2. Whyte P, Buchkovich KJ, Horowitz JM, Friend SH, Raybuck M, Weinberg RA et al: Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 1988; 334:124-129.
3. Arany Z, Newsome D, Oldread E, Livingston D, Eckner R: A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature 1995; 374:81-84.
4. Lundblad J, Kwok R, Laurance M, Harter M, Goodman R: Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CPB. Nature 1995; 374:85-88.
5. Sarnow P, Ho YS, Williams J, Levine AJ: Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell 1982; 28:387-394.
6. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW: Participation of p53 in the cellular response to DNA damage. Cancer Res 1991; 51:6304-6311.
7. Sabbatini P, Lin J, Levine A, White E: Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev 1995; 9:2184-2192.
8. Weinberg RA: The retinoblastoma gene and cell growth control. Trends Biochem Sci 1990; 15:199-202.
9. Knudson AGJ: Mutation and cancer: Statistical study of retinoblastomas. Proc Natl Acad Sci USA 1971; 68:820-823.
10. Weinberg RA: The retinoblastoma protein and cell cycle control. Cell 1995; 81:323-330.
11. Nevins JR: Mechanism of activation of early viral transcription by the adenovirus E1A gene product. Cell 1981; 26:213-220.
12. Ruley HE: Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature 1983; 304:602-606.
13. Lillie JW, Loewenstein PM, Green MR, Green M: Functional domains of adenovirus type 5 E1a proteins. Cell 1987; 50:1091-1100.
14. Moran E, Mathews MB: Multiple functional domains in the adenovirus E1A gene. Cell 1987; 48:177-178.
15. Whyte P, Ruley HE, Harlow E: Two regions of the adenovirus early region 1A proteins are required for transformation. J Virol 1988; 62:257-265.
16. Whyte P, Williamson NM, Harlow E: Cellular targets for transformation by the adenovirus E1A proteins. Cell 1989; 56:67-75.
17. Lee WH, Shew JY, Hong FD, Sety TW, Donoso LA, Young LJ et al.: The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity. Nature 1987; 329:642-645.
18. Mudryj M, Hiebert SW, Nevins JR: A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway. EMBO J 1990; 9:2179-2184.
19. Chellappan S, Hiebert S, Mudryj M, Horowitz J, Nevins J: The E2F transcription factor is a cellular target for the RB protein. Cell 1991; 65:1053-1061.
20. Bagchi S, Weinmann R, Raychaudhuri P: The retinoblastoma protein copurifies with E2F-1, and E1A-regulated inhibitor of the transcription factor E2F. Cell 1991; 65:1063-1072.
21. Bandara LR, La Thangue NB: Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature 1991; 351:494-497.
22. Sarnow P, Hearing P, Anderson CW, Halbert DN, Shenk T, Levine AJ: Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells. J Virol 1984; 49:692-700.
23. Raychaudhuri P, Bagchi S, Neill S, Nevins JR: Activation of the E2F transcription factor in adenovirus infected cells involves an E1A-dependent stimulation of DNA binding activity and induction of cooperative binding mediated by an E4 gene product. J Virol 1990; 64:2702-2710.
24. Buchkovich K, Duffy AL, Harlow E: The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 1989; 58:1097-1105.
25. DeCaprio JA, Ludlow JW, Lynch D, Furukawa Y, Griffin J, Piwnica-Worms H et al: The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 1989; 58:1085-1095.
26. Chen P-L, Scully P, Shew J-Y, Wang J, Lee W-H: Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 1989; 58:1193-1198.
27. Helin K, Lees JA, Vidal M, Dyson N, Harlow E, Fattaey A: A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 1992; 70:337-350.
28. Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/ cdk4. Nature 1993; 366:704-707.
29. Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA: Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994; 368:753-756.
30. Kamb A, Shattuck-Eidens D, Eeles R et al: Analysis of the p16 gene (cdkN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature Genetics 1994; 8:22-26.
31. DeCaprio JA, Ludlow JW, Figge J, Shew JY, Huang CM, Lee WH et al: SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 1988; 54:275-283.
32. Dyson N, Howley PM, Munger K, Harlow E: The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989; 243:934-937.
33. Lane DP, Crawford LV: T antigen is bound to a host protein in SV40-transformed cells. Nature 1979; 278:261-263.
34. Linzer DI, Levine AJ: Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 1979; 17:43-52.