메뉴 건너뛰기




Volumn 37, Issue 1, 1996, Pages 1-5

Concentration controlled and concentration defined clinical trials: Do they offer any advantages for antimicrobial chemotherapy?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT;

EID: 0029898046     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.1.1     Document Type: Editorial
Times cited : (5)

References (41)
  • 3
    • 0023176033 scopus 로고
    • Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bacterial activity and emergence of resistance
    • Blaser, J., Stone, B. B., Groner, M. C. & Zinner, S. H. (1987). Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bacterial activity and emergence of resistance Antimicrobial Agents and Chemotherapy 31, 1054-60.
    • (1987) Antimicrobial Agents and Chemotherapy , vol.31 , pp. 1054-1060
    • Blaser, J.1    Stone, B.B.2    Groner, M.C.3    Zinner, S.H.4
  • 4
    • 0026513661 scopus 로고
    • Prospective randomised phase II study of intravenous cefpirome 1 g or 2 g bd in the treatment of hospitalised patients with different infections
    • Carbon, C. & Cefpirome Study Group. (1992). Prospective randomised phase II study of intravenous cefpirome 1 g or 2 g bd in the treatment of hospitalised patients with different infections. Journal of Antimicrobial Chemotherapy 29, Suppl. A, 87-94.
    • (1992) Journal of Antimicrobial Chemotherapy , vol.29 , Issue.SUPPL. A , pp. 87-94
    • Carbon, C.1
  • 8
    • 0027457842 scopus 로고
    • Pharmacodynamic of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Psuedomonas sepsis
    • Drusano, G. L., Johnson, D. E., Rosen, M. & Standiford, H. C. (1993). Pharmacodynamic of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Psuedomonas sepsis. Antimicrobial Agents and Chemotherapy 37, 483-90.
    • (1993) Antimicrobial Agents and Chemotherapy , vol.37 , pp. 483-490
    • Drusano, G.L.1    Johnson, D.E.2    Rosen, M.3    Standiford, H.C.4
  • 10
    • 0028007333 scopus 로고
    • Relationship between plasma concentrations of 3′-deoxy-3′fluorothymidine (alovudine) and antinetroviral activity in two concentration-controlled trials
    • Flexner, C., van der Horst, C., Jacobson, M. A., Powderly, W., Duncanson, F., Ganes, D. et al. (1994). Relationship between plasma concentrations of 3′-deoxy-3′fluorothymidine (alovudine) and antinetroviral activity in two concentration-controlled trials. Journal of Infectious Diseases 170, 1394-403.
    • (1994) Journal of Infectious Diseases , vol.170 , pp. 1394-1403
    • Flexner, C.1    Van der Horst, C.2    Jacobson, M.A.3    Powderly, W.4    Duncanson, F.5    Ganes, D.6
  • 11
    • 0027197110 scopus 로고
    • Development of a population pharmacokinetic model and optimal sampling strategies for intravenous ciprofloxacin
    • Forrest, A., Ballow, C. H., Nix, D. E., Birmingham, M. C. & Schentag, J. J. (1993a). Development of a population pharmacokinetic model and optimal sampling strategies for intravenous ciprofloxacin. Antimicrobial Agents and Chemotherapy 37, 1065-72.
    • (1993) Antimicrobial Agents and Chemotherapy , vol.37 , pp. 1065-1072
    • Forrest, A.1    Ballow, C.H.2    Nix, D.E.3    Birmingham, M.C.4    Schentag, J.J.5
  • 15
    • 0025563353 scopus 로고
    • Concentration-dependent bacterial killing, adaptive resistance and post antibiotic effect of ciprofloxacin alone and in combination with gentamicin
    • Gould, I. M., Milne, K. & Jason, C. (1990). Concentration-dependent bacterial killing, adaptive resistance and post antibiotic effect of ciprofloxacin alone and in combination with gentamicin. Drugs Under Experimental and Clinical Research 16, 621-8.
    • (1990) Drugs under Experimental and Clinical Research , vol.16 , pp. 621-628
    • Gould, I.M.1    Milne, K.2    Jason, C.3
  • 17
    • 0006255843 scopus 로고
    • A review of the pharmacokinetics and side effects of cefuroxime axetil
    • Emmerson, A. M., Ed, Royal Society of Medicine Services International Congress and Symposium Series, no. 124. Royal School of Medicine, London
    • Kelsey, M C. (1987). A review of the pharmacokinetics and side effects of cefuroxime axetil. In The Management of Lower Respiratory Tract Infections with Cefuroxime Axetil (Emmerson, A. M., Ed), pp. 25-33 Royal Society of Medicine Services International Congress and Symposium Series, no. 124. Royal School of Medicine, London.
    • (1987) The Management of Lower Respiratory Tract Infections with Cefuroxime Axetil , pp. 25-33
    • Kelsey, M.C.1
  • 18
    • 0026505919 scopus 로고
    • A double-blind study of two dosage regimens of lomefloxacin in bacteriogically proven exacerbation's of chronic bronchitis of Gram-negative ethology
    • Kemper, P. & Kohler, D. (1992). A double-blind study of two dosage regimens of lomefloxacin in bacteriogically proven exacerbation's of chronic bronchitis of Gram-negative ethology. American Journal of Medicine 92, Suppl. 4A, 98-102.
    • (1992) American Journal of Medicine , vol.92 , Issue.SUPPL. 4A , pp. 98-102
    • Kemper, P.1    Kohler, D.2
  • 19
    • 0027934721 scopus 로고
    • Ciprofloxacin resistant Serratia marcescens endocarditis as a complication of non-Hodgkin's lymphoma
    • Körner, R. J., Nicol, A., Reeves, D. S., MacGowan, A. P. & Hows, J. (1994). Ciprofloxacin resistant Serratia marcescens endocarditis as a complication of non-Hodgkin's lymphoma. Journal of Infection 29, 73-6.
    • (1994) Journal of Infection , vol.29 , pp. 73-76
    • Körner, R.J.1    Nicol, A.2    Reeves, D.S.3    MacGowan, A.P.4    Hows, J.5
  • 21
    • 0027478845 scopus 로고
    • Concentration-controlled versus concentration-defined clinical trials
    • Levy, G. (1993). Concentration-controlled versus concentration-defined clinical trials. Clinical Pharmacology and Therapeutics 53, 385-8.
    • (1993) Clinical Pharmacology and Therapeutics , vol.53 , pp. 385-388
    • Levy, G.1
  • 23
    • 0027379397 scopus 로고
    • Dose-response and concentration-response relationships: Clinical and regulatory perspectives
    • Leiberman, R. & Nelson, R. (1993). Dose-response and concentration-response relationships: clinical and regulatory perspectives. Therapeutic Drug Monitoring 15, 498-502.
    • (1993) Therapeutic Drug Monitoring , vol.15 , pp. 498-502
    • Leiberman, R.1    Nelson, R.2
  • 24
    • 0027251546 scopus 로고
    • Dose response evaluation. Use of plasma concentration confidence intervals as a tool to predict optimal drug dose ratio
    • Lønning, P. E. (1993). Dose response evaluation. Use of plasma concentration confidence intervals as a tool to predict optimal drug dose ratio. Clinical Pharmacokinetics 25, 1-5.
    • (1993) Clinical Pharmacokinetics , vol.25 , pp. 1-5
    • Lønning, P.E.1
  • 26
    • 9244239212 scopus 로고
    • Once daily aminoglycosides therapy: Serum monitoring and clinical indications
    • MacGowan, A. P. (1994). Once daily aminoglycosides therapy: serum monitoring and clinical indications. Syva Drug Monitor 1, 1-6.
    • (1994) Syva Drug Monitor , vol.1 , pp. 1-6
    • MacGowan, A.P.1
  • 28
    • 0028608129 scopus 로고
    • Serum aminoglycoside concentrations: The case for routine monitoring
    • MacGowan, A. P. & Reeves, D. S. (1994). Serum aminoglycoside concentrations: the case for routine monitoring. Journal of Antimicrobial Chemotherapy 34, 829-37.
    • (1994) Journal of Antimicrobial Chemotherapy , vol.34 , pp. 829-837
    • MacGowan, A.P.1    Reeves, D.S.2
  • 30
    • 0023119430 scopus 로고
    • Clinical response to aminoglycoside therapy: Importance of ratio of peak concentration to minimal inhibitory concentration
    • Moore, R. D., Leitman, P. S. & Smith, C. R. (1987). Clinical response to aminoglycoside therapy: importance of ratio of peak concentration to minimal inhibitory concentration. Journal of Infectious Diseases 155, 93-9.
    • (1987) Journal of Infectious Diseases , vol.155 , pp. 93-99
    • Moore, R.D.1    Leitman, P.S.2    Smith, C.R.3
  • 31
    • 0027478845 scopus 로고
    • Concentration-controlled versus concentration-defined clinical trials-reply
    • Peck, C. C. (1993). Concentration-controlled versus concentration-defined clinical trials-reply. Clinical Pharmacology and Therapeutics 53, 385-7.
    • (1993) Clinical Pharmacology and Therapeutics , vol.53 , pp. 385-387
    • Peck, C.C.1
  • 32
    • 0028128511 scopus 로고
    • Meropenem: A new carbapenem antimicrobial
    • Pryka, R. D. & Haig, G. M. (1994) Meropenem: a new carbapenem antimicrobial. Annals of Pharmacotherapy 28, 1045-54.
    • (1994) Annals of Pharmacotherapy , vol.28 , pp. 1045-1054
    • Pryka, R.D.1    Haig, G.M.2
  • 33
    • 0028967964 scopus 로고
    • Therapeutic monitoring of antimicrobials: A summary of the information presented at the UK. NEQAS for antibiotic assays for participants October 1993
    • Reeves, D. S., MacGowan, A. P., Holt, H. A., Lovering, A. M., Warnock, D. W. & White, L. O. (1995) Therapeutic monitoring of antimicrobials: a summary of the information presented at the UK. NEQAS for antibiotic assays for participants October 1993. Journal of Antimicrobial Chemotherapy 35, 213-26.
    • (1995) Journal of Antimicrobial Chemotherapy , vol.35 , pp. 213-226
    • Reeves, D.S.1    MacGowan, A.P.2    Holt, H.A.3    Lovering, A.M.4    Warnock, D.W.5    White, L.O.6
  • 34
    • 0028046352 scopus 로고
    • A randomised trial comparing fluconazole with amphoteracin B for the treatment of candidemia in patients without neutropenia
    • Rex, J. H., Bennett, J. E , Sugar, A. M., Pappas, P. G., van der Horst, C. M., Edwards, J. E. et al. (1994). A randomised trial comparing fluconazole with amphoteracin B for the treatment of candidemia in patients without neutropenia. New England Journal of Medicine 331, 1325-30.
    • (1994) New England Journal of Medicine , vol.331 , pp. 1325-1330
    • Rex, J.H.1    Bennett, J.E.2    Sugar, A.M.3    Pappas, P.G.4    Van der Horst, C.M.5    Edwards, J.E.6
  • 35
    • 0027096496 scopus 로고
    • A world-wide clinical overview of lomefloxacin, once daily fluoroquinolone
    • Rizk, E. (1992). A world-wide clinical overview of lomefloxacin, once daily fluoroquinolone International Journal of Antimicrobial Agents 2, 67-78.
    • (1992) International Journal of Antimicrobial Agents , vol.2 , pp. 67-78
    • Rizk, E.1
  • 36
    • 0026320316 scopus 로고
    • The randomised concentration-controlled trial an evaluation of its sample size efficiency
    • Sanathanan, L. P. & Peck, C. C. (1991). The randomised concentration-controlled trial an evaluation of its sample size efficiency. Controlled Clinical Trials 12, 780-94.
    • (1991) Controlled Clinical Trials , vol.12 , pp. 780-794
    • Sanathanan, L.P.1    Peck, C.C.2
  • 37
    • 0025991702 scopus 로고
    • Randomisation, PK-controlled dosing, and titration: An integrated approach for designing clinical trials
    • Sanathanan, L. P., Peck, C. C., Temple, R., Lieberman, R. & Pledger, G. (1991). Randomisation, PK-controlled dosing, and titration: an integrated approach for designing clinical trials. Drug Information Journal 25, 425-31.
    • (1991) Drug Information Journal , vol.25 , pp. 425-431
    • Sanathanan, L.P.1    Peck, C.C.2    Temple, R.3    Lieberman, R.4    Pledger, G.5
  • 38
    • 0028557425 scopus 로고
    • Why monitor peak vancomycin concentration?
    • Saunders, N. J. (1994). Why monitor peak vancomycin concentration? Lancet 344, 1748-50.
    • (1994) Lancet , vol.344 , pp. 1748-1750
    • Saunders, N.J.1
  • 39
    • 0027436871 scopus 로고
    • The use of concentration measurements of parent drug and metabolites during clinical trials
    • Shaw, L. M., Bonner, H. S., Fields, L. & Leiberman, R. (1993). The use of concentration measurements of parent drug and metabolites during clinical trials. Therapeutic Drug Monitoring 15, 483-7.
    • (1993) Therapeutic Drug Monitoring , vol.15 , pp. 483-487
    • Shaw, L.M.1    Bonner, H.S.2    Fields, L.3    Leiberman, R.4
  • 41
    • 0027220096 scopus 로고
    • Chemoprophylaxis for candidosis and aspergillosis in neutropenia and transplantation. A review and recommendations
    • Working Party Report of the British Society for Antimicrobial Chemotherapy (1993) Chemoprophylaxis for candidosis and aspergillosis in neutropenia and transplantation. a review and recommendations. Journal of Antimicrobial Chemotherapy 32, 5-21.
    • (1993) Journal of Antimicrobial Chemotherapy , vol.32 , pp. 5-21


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.