Lipoprotein(a) inhibits collagen-induced aggregation of thrombocytes

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 5, 1996, Pages 648-655

  Gries, Anna ^a   Gries, Maria ^a   Wurm, Helmut ^a   Kenner, Thomas ^a   Ijsseldijk, Martin ^c   Sixma, Jan J ^a   Kostner, Gert M ^b  

^a Institute of Adaptive and Spaceflight Physiology   (Austria)

^b Institute of Medical Biochemistry   (Austria)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

lipoprotein(a); platelet adhesion; platelet aggregation; serotonin release; thromboxane A2

Indexed keywords

COLLAGEN; LIPOPROTEIN A;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LIPID ANALYSIS; PRIORITY JOURNAL; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION;

EID: 0029897984     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.5.648     Document Type: Article

References (48)

1. MBewu AD, Durrington PN. Lipoprotein(a): structure, properties and possible involvement in thrombogenesis and atherogenesis. Atherosclerosis. 1990;85:1-14.
2. Utermann G, Weber W. Protein composition of Lp(a) lipoprotein from human plasma. FEBS Lett. 1983;154:357-361.
3. Gaubatz JW, Chari MV, Nava ML, Guyton JR, Morrisett JD. Isolation and characterization of the two major apoproteins in human lipoprotein(a). J Lipid Res. 1987;28:69-79.
4. Kostner GM, Avogaro P, Cazzolato G, Marth E, Bittolo-Bon G. Lipoprotein Lp(a) and the risk for myocardial infarction. Atherosclerosis. 1981;38:51-61.
5. Armstrong VW, Cremer P, Eberle E, Manke A, Schulze F, Wieland H, Kreuzer H, Seidel D. The association between serum Lp(a) concentrations and angiographically assessed coronary atherosclerosis. Atherosclerosis. 1986;62:249-257.
6. Gushing GL, Gaubatz JW, Nava ML, Burdick BJ, Bocan TMA, Guyton JR, Weilbaecher D, DcBakey ME, Lawrie GM, Morrisett JD. Quantitation and localization of apolipoproteins(a) and B in coronary artery bypass vein grafts resected at reoperation. Arteriosclerosis. 1989;9:593-603.
7. Seed M, Hoppichler F, Reaveley D, McCarthy S, Thompson GR, Boerwinkle E, Utermann G. Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med. 1990;322:1494-1499.
8. McLean JW, Tomlinson JE, Kuang WJ, Eaton DL, Chen EY, Fless GM, Scanu AM, Lawn RM. cDNA sequence of human apolipoprotein(a) is homologous to plasminogen. Nature. 1987; 330:132-137.
9. Karadi I, Kostner GM, Gries A, Nimpf J, Romics L, Malle E. Lipoprotein (a) and plasminogen are immunochemically related. Biochim Biophys Acta. 1988;960:91-97.
10. Bihari-Varga M, Gruber E, Rotheneder M, Zechner R. Kostner GM. Interaction of lipoprotein(a) and low-density lipoprotein with glycosaminoglycans from human aorta. Arteriosclerosis. 1988;8: 851-857.
11. Zioncheck TF, Powell LM, Rice GC, Eaton DL, Lawn RM. Interaction of recombinant apolipoprotein(a) and lipoprotein(a) with macrophages. J Clin Invest. 1991;87:767-771.
12. Salonen E, Jauhiainen M, Zardi L, Vaheri A, Ehnholm C. Lipoprotein(a) binds to fibronectin and has serine protease activity capable of cleaving it. EMBO J. 1991;8:4035-4040.
13. Kluft C, Jie AFH, Los P, DeWit E, Havekes L. Functional analogy between lipoprotein(a) and plasminogen in the binding to the kringle 4 binding protein tetranectin. Biochem Biophys Res Commun. 1989;161:427-433.
14. McConathy WJ, Trieu VN. Lp(a) interactions. Prog Lipid Res. 1991; 30:195-203.
15. Kostner GM, Grillhofer H. Lipoprotein(a) mediates high affinity low density lipoprotein association to receptor negative fibroblasts. J Biol Chem. 1991;266:21287-21292.
16. Rossi EC. The function of platelets in hemostasis. Med Clin North Am. 1972;56:25-38.
17. Jaffe R, Deykin D. Evidence for a structural requirement for the aggregation of platelets by collagen. J Clin Invest. 1974;53:875-883.
18. Aviram M, Brook JG. Platelet activation by plasma lipoproteins. Prog Cardiovasc Dis. 1987;30:61-72.
19. Aviram M, Brook JG. Platelet interaction with high- and low-density lipoproteins. Atherosclerosis. 1983;46:259-268.
20. Weber K, Osborne M. The reliability of molecular weight determination by dodecylsulfate polyacrylamide gel electrophoresis. J Biol Chem. 1969;244:4406-4412.
21. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA. 1979;76: 4350-4354.
22. Hatch FT, Lees RS. Practical methods for plasma lipoprotein analysis. Adv Lipid Res. 1968;6:1-8.
23. Jürgens G, Kostner GM. Studies on the structure of the Lp(a) lipoprotein: isolation and partial characterization of the Lp(a)-specific antigen. Immunogenetics. 1975;1:560-569.
24. Tangen O, Berman HJ, Marfey P. Gel filtration: a new technique for separation of blood platelets from plasma. Thromb Diathes Haemorrh. 1971;25:268-278.
25. Mustard JF, Packham MA, Kinlough-Rathbone RL, Perry DW, Regoeczi E. Fibrinogen and ADP-induced platelet aggregation. Blood. 1978;52:453-457.
26. Born GVR. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature. 1962;194:927-930.
27. Surya II, Gorter G, Mommersteeg M, Akkerman JWN. Enhancement of platelet functions by low density lipoproteins. Biochim Biophys Acta. 1992;1165:19-26.
28. Ostfeld I, Dadosh-Goffer N, Borokowski S, Talmon J, Mani A, Zor U, Lahav J. Lupus anticoagulant antibodies inhibit collagen-induced adhesion and aggregation of human platelets in vitro. J Clin Immunol. 1992;12:415-423.
29. Houdijk WPM, Sakariassen KJ, Niefelstein PFEM, Sixma JJ. Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III. J Clin Invest. 1985;75:531-540.
30. Sakariassen KS, Aarts PAMM, de Groot PC, Houdijk WPM, Sixma JJ. A perfusion chamber developed to investigate platelet interaction in flowing blood with human vessel wall cells, their extracellular matrix, and purified components. J Lab Clin Med. 1983;102: 522-535.
31. Zwaginga JJ, Sixma JJ, de Groot PG. Activation of endothelial cells induces platelet thrombus formation on their matrix: studies of new in vitro thrombosis model with low-molecular-weight heparin as anticoagulant. Arteriosclerosis. 1990;10:49-62.
32. Wieland H, Seidel D. Quantitative lipoprotein electrophoresis. In: Lewis LA, ed. Handbook of Electrophoresis, III. Boca Raton, Fla: CRC Press; 1983:83-102.
33. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193: 265-275:
34. Utermann G, Menzel HJ, Kraft HG, Duba HC, Kemmler HG, Seitz C. Lp(a) glycoprotein phenotypes: inheritance and relation to Lp(a)-lipoprotein concentrations in plasma. J Clin Invest. 1987;80: 458-465.
35. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
36. Aviram M, Brook JG. Platelet interaction with high and low density lipoproteins. Atherosclerosis. 1983;46:259-268.
37. Bruckdorfer KR. The effect of plasma lipoproteins on platelet responsiveness and on platelet and vascular prostanoid synthesis. Prostaglandins Leukot Essent Fatty Acids, 1989;38:247-254.
38. Koller E, Koller F. Binding characteristics of homologous plasma lipoproteins to human platelets. Methods Enzymol. 1992;215: 383-398.
39. Surya II, Akkerman JWN. The influence of lipoproteins on blood platelets. Am Heart J. 1993;125:272-274.
40. Aviram M, Brook JG. The effect of blood constituents on platelet function: role of blood cells and plasma lipoproteins. Artery. 1983; 11:297-305.
41. Kostner GM, Gries A, Pometta M, Molinari E, Pichler P, Aicher H. Immunochemical determination of lipoprotein Lp(a): comparison of Laurell electrophoresis and ELISA. Clin Chim Acta. 1990;188: 187-192.
42. Nimpf J, Nimpf M, Gries A, Pfeiffer KP, Wurm H, Kostner GM. Plasma lipids, lipoproteins and apoproteins in relation to platelet activation in normolipemic persons. Atheroma. 1986;1:10-15.
43. Ding YA, Chou TC, Lin KC. Effects of long-acting propranolol and verapamil on blood pressure, platelet function, metabolic and rheological properties in hypertension. J Hum Hypertens. 1994;8: 273-278.
44. Ardlie NG, Selley ML, Simons LA. Platelet activation by oxidatively modified low density lipoproteins. Atherosclerosis, 1989;76: 117-124.
45. Sixma JJ, Van Zanten GH, Saelman HUM, Verkleij M, Lankhof H, Nieuwenhuis HK, De Groot PG. Platelet adhesion to collagen. Thromb Haemost. 1995;74:454-459.
46. Saelman EUM, Nieuwenhuis HK, Hese KM, De Groot PG, Heijnen HFG, Sage EH, William S, McKeown L, Gralnick HR, Sixma JJ. Platelet adhesion to collagen types 1 through VIII under conditions of stasis and flow is mediated by GPIa/IIa (α2β1-integrin). Blood. 1994;83:1244-1250.
47. Ezratty A, Simon DI, Loscalzo J. Lipoprotein(a) binds to human platelets and attenuates plasminogen binding and activation. Biochemistry. 1993;32:4628-4633.
48. Malle E, Ibovnik A, Steinmetz G, Kostner GM, Sattler W. Identification of glycoprotein lib as the lipoprotein(a)-binding protein on platelets: lipoprotein(a) binding is independent of an arginyl-glycyl-aspartate tripeptide located in apolipoprotein(a). Arterioscler Thromb. 1994;14:345-352.