Proliferation index and vascular density of giant cell tumors of bone. Are they prognostic markers?

Cancer

Volumn 77, Issue 10, 1996, Pages 2044-2051

  Sulh, Muhammadsamir A ^a   Greco, M Alba ^a,b   Jiang, Tony ^c   Goswami, Sunanda B ^a   Present, David ^c   Steiner, German ^c  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c NYU HOSPITAL FOR JOINT DISEASES   (United States)

Author keywords

Angiogenesis; CD 34; Giant cell tumor of bone; Image analysis; Ki 67; MIB 1; Proliferation index; QBEND 10; Vascular density

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CANCER RECURRENCE; CELL PROLIFERATION; CLINICAL ARTICLE; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; OSTEOCLASTOMA; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; TUMOR VASCULARIZATION;

ADOLESCENT; ADULT; BONE NEOPLASMS; CELL DIVISION; FEMALE; GIANT CELL TUMORS; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOVASCULARIZATION, PATHOLOGIC; PREDICTIVE VALUE OF TESTS; PROGNOSIS;

EID: 0029897835     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19960515)77:10<2044::AID-CNCR12>3.0.CO;2-V     Document Type: Article

References (65)

1. Ladanyi M, Traganos F, Huvos AG. Benign metastasizing giant cell tumors of bone. A DNA flow cytometric study. Cancer 1989;64:1521-6.
2. Xiang JH, Spanier SS, Benson NA, Braylan RC. Flow cytometric analysis of DNA in bone and soft tissue tumors using nuclear suspension. Cancer 1987;59:1951-8.
3. Mankin HJ, Connor JF, Schiller AL, Perlmutter N, Alho A, McGuire M. Grading of bone tumors by analysis of nuclear DNA content using flow cytometry. J Bone Joint Surg Am 1985;67:404-13.
4. Scott SM, Pritchard DJ, Unni KK, Rainwater LM, Lieber MM. "Benign" metastasizing giant cell tumor evaluation of nuclear DNA patterns by flow cytometry. J Orthop Res 1989;7:463-7.
5. Hall PA, Levison DA. Review: assessment of cell proliferation in histological material. J Clin Pathol 1990;43:184-92.
6. Quinn CM, Wright NA. The usefulness of clinical measurement of cell proliferation in gynecological cancer (Review). Int J Gynaecol Pathol 1992;112:131-43.
7. Liotta LA, Kleinerman J, Saidel GM. Quantitative relationships of intravascular tumor cells, tumor vessels and pulmonary metastasis following tumor implantation. Cancer Res 1974;34:997-1004.
8. Yamazaki K, Abe S, Takekawa H, Sukoh N, Watanabe N, Ogura S, et al. Tumor angiogenesis in human lung adenocarcinoma. Cancer 1994;74:2245-50.
9. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
10. Bosari S, Lee AKC, Delellis RA, Wiley BD, Heatley GJ, Silverman ML. Microvessel quantitation and prognosis in invasive breast carcinoma. Hum Pathol 1992;23:755-61.
11. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992;84:1875-87.
12. Weidner N, Carrol PR, Flax J, Blumenfeld W, Folkman J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol 1993;143:401-9.
13. Wakui S, Furusato M, Itoh T, Sasaki H, Akiyana A, Kinoshita I, et al. Tumor angiogenesis in prostatic carcinoma with and without bone marrow metastasis: a morphometric study. J Pathol 1992;168:257-62.
14. Macchiarini P, Fontanini G, Hardin MJ, Squartini F, Angeletti CA. Relations of neovascularization to metastasis of nonsmall-cell lung cancer. Lancet 1992;340:145-6.
15. Zhu X, Steiner G. Malignant giant cell tumor of bone: malignant transformation of a benign giant cell tumor treated by surgery. Bull Hosp Jt Dis Orthop Inst 1990;50(2):169-76.
16. Erler BS, Chein K, Marchevsky AM. An image analysis workstation for the pathology laboratory. Mod Pathol 1993; 65:612-8.
17. Dahlin DC, Unni KK. Bone tumors: general aspects and data on 8,542 cases. 4th edition. Springfield, IL: Charles C Thomas, 1986:337.
18. Hutter RVP, Worcester JN Jr, Frances KC, Foote FW Jr, Stewart FW. Benign and malignant giant cell tumors of bone. A clinicopathologic analysis of the natural history of the disease. Cancer 1962;15:653-90.
19. Huvos A. Giant cell tumor of bone. In: Huvos A, editor. Bone tumors, diagnosis, treatment and prognosis. 2nd edition. Philadelphia: WB Saunders Co., 1991:429-67.
20. Fechner RE, Mills SE. Tumors of the bones and joints. Fascicle 8. Third series. Washington DC: Armed Forces Institute of Pathology 1993;173.
21. Sadler DW, Coghill SB. Histopathologists, malignancies and undefined high-power fields. Lancet 1989;1:785-6.
22. Key G, Becker MH, Baron B, Duchrow M, Schluter C, Flad HD, et al. New Ki-67-equivalent murine monoclonal antibodies (MIB1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 66 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest 1993;68:629-36.
23. Drobnjak M, Latres E, Pollack D, Karpeh M, Dudas M, Woodruff JM, et al. Prognostic implications of p53 nuclear over expression and high proliferation index of Ki-67 in adult soft tissue sarcomas. J Natl Cancer Inst 1994;86:549-54.
24. Ooe M, Nogita T, Kawashima M. Comparative study of Ki-67 immunostaining and nuclear DNA content in histiofibrous tumors. J Dermatol 1992;19:12-8.
25. Barnard NJ, Hall PA, Lemoine NR, Kadar N. Proliferative index in breast carcinoma determined in situ by Ki-67 immunostaining and its relationship to clinical and pathologic variables. J Pathol 1987;152:287-95.
26. Raymond WA, Leong AS, Bolt JW, Milio J, Jose JS. Growth fractions in human prostatic carcinoma determined by Ki-67 immunostaining. J Pathol 1988;156:161-7.
27. Cheville JC, Terrell RB, Cohen MB. Use of proliferative markers Ki-67 (MIB-1) and proliferating cell nuclear antigen (PC10) in transitional cell carcinoma of the renal pelvis. Mod Pathol 1994;7:794-800.
28. Burger PC, Shibata T, Kleihues P. The use of monoclonal antibody Ki-67 in the identification of proliferating cell: application to surgical neuropathology. Am J Surg Pathol 1986;10:611-7.
29. Zagzag D, Friedlander DR, Miller DC, Dosik J, Cangiarella J, Kostianovsky M, et al. Tenascin expression in astrocytomas correlates with angiogenesis. Cancer Res 1995;55:907-14.
30. Pence JC, Kerns BJ, Dodge RK, Iglehart JD. Prognostic significance of the proliferation index in surgically resected non-small-cell lung cancer. Arch Surg 1993;128:1382-90.
31. Weiss LM, Strickler JG, Medeiros LJ, Gerdes J, Stein H, Warnke RA. Proliferative rates of non-Hodgkin's lymphomas as assessed by Ki-67 antibody. Hum Pathol 1987;18:1155-9.
32. deRiese WTW, Crabtree WN, Allhoff EP, Werner M, Liedke S, Lenis G, et al. Prognostic significance of Ki-67 Immunostaining in non metastatic renal cell carcinoma. J Clin Oncol 1993;11:1804-8.
33. Pich A, Valente G, Azzoni L, Stramignoni A, Margaria E, Tasso M. Argyrophillic nuclear organizer region counts and Ki-67 scores in human renal cell carcinoma. Path Res Pract 1991;187:482-6.
34. de Peralta-Venturina M, Amin MB, Keoleian CM, Schultz DS, Kubus JJ, Linden MD, et al. Papillary renal cell carcinoma. Assessment of proliferative activity using PCNA and MIB-1 (Ki-67) and correlation with clinicopathologic findings. Appl Immunohistochem 1994;2:241-7.
35. DeLellis RA. Does the evaluation of proliferative activity predict malignancy or prognosis in endocrine tumors? Hum Pathol 1995;26:131-4.
36. Goldblum JR, Shannon R, Kaldjian EP, Thiny M, Davenport R, Thompson N, et al. Immunohistochemical assessment of proliferative activity in adrenocortical neoplasms. Mod Pathol 1993;6:663-8.
37. Carr K, Heffess C, Jin L, Lloyd RV. Immunohistochemical analysis of thyroid carcinomas utilizing antibodies to P53 and Ki-67. Appl Immunohistochem 1993;1:201-7.
38. Katoh R, Bray CE, Suzuki K, Komiyama A, Hemmi A, Kawaoi A, et al. Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1. Hum Pathol 1995;26:139-46.
39. Abbona GC, Papotti M, Gasparri G, Bussolati G. Proliferative activity in parathyroid tumors as detected by Ki-67 immunostaining. Hum Pathol 1995;26:135-8.
40. Kitz K, Knosp E, Koos WT, Korn A. Proliferation in pituitary adenomas: measurement by Mab Ki-67. Acta Neurochir (Wien) 1991;53(Suppl):60-4.
41. Scotlandi K, Serra M, Manara C, Maurici D, Benini S, Nini G, et al. Clinical relevance of Ki-67 expression in bone tumors. Cancer 1995;75:806-14.
42. Linden MD, Ma CK, Kubus J, Brown RD, Zarbo RJ. Ki-67 and proliferating cell nuclear antigen tumor proliferative indices in DNA diploid colorectal adenocarcinomas. Correlation with histopathologic characteristics and cell cycle analysis with two-color DNA flow cytometry. Am J Clin Pathol 1993;100:206-12.
43. Cheung ANY, Ngan HYS, Collins RJ, Wong YL. Assessment of cell proliferation in hydatidiform mole using monoclonal antibody MIB1 to Ki-67 antigen. J Clin Pathol 1994;47:601-4.
44. Kerns BJ M, Jordan PA, Faerman LL, Berchuck A, Bast RC Jr, Layfield LJ. Determination of proliferation index with MIB-1 in advanced ovarian cancer using quantitative image analysis. Am J Clin Pathol 1994;101:192-7.
45. Hori K, Suzuki M, Tanda S, Saito S. In vivo analysis of tumor vascularization in the rat. Jpn J Cancer Res 1990;81:279-88.
46. Ingber DE, Folkman J. Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix. J Cell Biol 1989;109:317-30.
47. Rastinejad F, Polverini PJ, Bouck NP. Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene. Cell 1989;56:345-55.
48. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82:4-6.
49. Rofstad EK. Growth and vascular structure of human melanoma xenografts. Cell Tissue Kinet 1984;17:91-101.
50. Folkman J, Klagsburn M. Angiogenic factors. Science 1987; 235:442-7.
51. Polverini PJ, Leibovich SJ. Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages. Lab Invest 1984;51:635-42.
52. Blood CH, Zetter BR. Tumor interactions with the vasculature: angiogenesis and tumor metastasis. Biochim Biophys Acta 1990;1032:89-118.
53. Schlingemann RO, Rietveld FJ, de Waal RM, Bradley NJ, Skene AI, Davies AJ, et al. Leukocyte antigen CD-34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. Lab Invest 1990;62:690-6.
54. Ramani P, Bradley NJ, Fletcher CD. QBEND/10, a new monoclonal antibody to endothelium: assessment of its diagnostic utility in paraffin sections. Histopathology 1990; 17:237-42.
55. Traweek ST, Kandalaft PL, Mehta P, Battifora H. The human hematopoietic progenitor cell antigen (CD-34) in vascular neoplasia. Am J Clin Pathol 1991;96:25-31.
56. Weiss SW, Nickoloff BJ. CD-34 is expressed by distinctive cell population in peripheral nerve, nerve sheath tumor, and related lesions. Am J Surg Pathol 1993;17:1039-45.
57. Miettinen M, Virolainen M, Rikala MS. Gastrointestinal stromal tumors - Value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol 1995;19:207-16.
58. Brem S, Cotran R, Folkman J. Tumor angiogenesis: a quantitative method for histologic grading. J Natl Cancer Inst 1972;48:347-56.
59. Brawer MK, Deering RE, Brown M, Preston SD, Bigler SA. Predictors of pathologic stage in prostate carcinoma. The role of neovascularity. Cancer 1994;73:678-87.
60. Barbareschi M, Weidner N, Gasparini G, Morelli L, Forti S, Eccher C, et al. Microvessel density quantification in breast carcinomas. Appl Immunohistochem 1995;3:75-84.
61. Sukoh N, Abe S, Nakajima I, Ogura S, Isobe H, Inoue K, et al. Immunohistochemical distributions of cathepsin B an basement membrane antigens in human lung adenocarcinoma: association with invasion and metastasis. Virchows Arch 1994;424:33-8.
62. Nakajima I. Immunohistochemical study of the extracellular matrix in non-small cell lung cancer: relation to lymph node metastasis and prognosis. Hokkaido J Med Sci 1991;66:356-68.
63. Sukoh N, Abe S, Ogura S, Isobe H, Takekawa H, Inoue K, et al. Immunohistochemical study of cathespin B. Prognostic significance in human lung cancer. Cancer 1994;74:46-51.
64. Mignatti P, Rifkin DB. Biology and biochemistry of protein-ases in tumor invasion. Physiol Rev 1993;73:161-95.
65. Schoedel KE, Greco MA, Stetler-Stevenson WG, Present D, Steiner GC. Expression of metalloproteinases and tissue inhibitors of metalloproteinases in giant cell tumor of bone: an immunohistochemical study with clinical correlation. Mod Pathol 1995;8:11A.