Noradrenergic transmission in the tail artery of hypertensive rats transgenic for the mouse renin gene Ren-2

Journal of Autonomic Pharmacology

Volumn 16, Issue 2, 1996, Pages 69-77

  Arribas, S M ^a,b   Alonso, M J ^a   Marin J ^a   Fernandes, F ^a   Llergo, J L ^a   Sanchez Ferrer C F ^a   Salaices, M ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; PHENTOLAMINE; PRAZOSIN; PROPRANOLOL; TETRODOTOXIN; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; HYPERTENSION; MALE; MOUSE; NONHUMAN; NORADRENALIN RELEASE; NORADRENERGIC SYSTEM; RAT; SYNAPTIC TRANSMISSION; VASOCONSTRICTION; VASODILATATION;

EID: 0029897633     PISSN: 01441795     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1474-8673.1996.tb00414.x     Document Type: Article

References (45)

1. ALBERT, V. & CAMPBELL, G.R. (1990). Relationship between sympathetic nervous system and vascular smooth muscle: a morphometric study of adult and juvenile spontaneously hypertensive rat/Wistar-Kyoto rat caudal artery. Heart Vessels, 5, 129-139.
2. ANTONACCIO, M.J. & KERWIN, L. (1981) Pre- and postjunctional inhibition of vascular sympathetic function by captopril in SHR. Implication of vascular angiotensin II in hypertension and antihypertensive actions of captopril. Hypertension, 3(suppl I), I-54-I-62.
3. ARRIBAS, S., SANCHEZ-FERRER, C.F., PEIRO, C., PONTE, A., SALAICES, M. & MARİN, J. (1994). Functional vascular renin-angiotensin system in hypertensive transgenic rats for the mouse renin gene Ren-2. Gen. Pharmacol., 25, 1163-1170.
4. ATKINSON, J., TRESCASES, N., BENEDEK, C., BOILLAT, N., FOUDA, A.K., KRAUSE, F., PITTON, M.C., RAFIZADEH, C., DE RIVAZ, J.C., SAUTEL, M. & SONNAY, M. (1988). Alpha-1 and alpha-2 adrenoceptor agonists induce vasoconstriction of the normotensive rat caudal artery in vitro by stimulation of a heterogeneous population of alpha-1 adrenoceptors. Naunyn-Schmiedeberg's Arch. Pharmacol., 338, 529-535.
5. BAO, J.X., KRIKSSON, I.E. & STJÁRNE, L. (1990). Neurotransmitter and pre- and post-junctional receptors involved in the vasoconstrictor response to sympathetic nerve stimulation in rat tail artery. Acta Physiol. Scand., 140, 467-479.
6. BOROWSKI, K.R. (1988). Pre- and postjunctional β-adrenoceptors and hypertension. J. Auton. Pharmacol., 8, 153-171.
7. CASSIS, L.A., STITZEL, R.E. & HEAD, R.J. (1985). Hypernoradrenergic innervation of the caudal artery of the spontaneously hypertensive rat: an influence upon neuroeffector mechanism. J. Pharmacol. Exp. Ther., 234, 792-803.
8. DE CHAMPLAIN, J. (1990). Pre- and postsynaptic adrenergic dysfunctions in Hypertension. J. Hypertens., 8(suppl 7), S77-S85.
9. 2-adrenoceptors in rabbit isolated distal saphenous artery. A permissive role for angiotensin II? Br. J. Pharmacol., 96, 259-261.
10. 2-adrenoceptors in rabbit isolated blood vessels. Br. J. Pharmacol., 103, 1475-1483.
11. DZAU, V.J. (1986). Significance of the vascular renin-angiotensin pathway Hypertension, 8, 553-559.
12. FARIA, F.A. & SALGADO, M.C.O. (1992). Facilitation of noradrenergic transmission by angiotensin in hypertensive rats. Hypertension, 19(suppl II), II-30-II-35.
13. FELDMAN, R.D. (1987). β-adrenergic receptor alteration in hypertension: physiological and molecular correlates. Can. J. Physiol. Pharmacol., 64, 1666-1672.
14. FLEMING, W.W., WESTFALL, D.P., DE LA LANDE, I.S. & JELET, L.B. (1972). Long normal distribution of equieffective doses of norepinephrine and acetylcholine in several tissues. J. Pharmacol. Exp. Ther., 181, 330-345.
15. FUJIMOTO, S., DOHI, Y., AOKI, K. & MATSUDA, T. (1987) Altered beta-adrenoceptor mediated relaxation in deocorticosterone-salt hypertensive rats. J. Pharmacol. Exp. Ther., 233, 716-723.
16. GANTEN, D. (1993). The transition from experimental to clinical pharmacology: the renin-angiotensin paradigm. J. Cardiovasc. Pharmacol., 22(suppl. 1), S14-S29.
17. HlLGERS, K.F., PETERS, J., VEELKEN, R., SOMMER, M., RUPPRECHT, G., GANTEN, D., LUFT, F.C. & MANN, J.F. (1992). Increased vascular angiotensin formation in female rats harbouring the mouse Ren-2 gene. Hypertension, 19, 687-691.
18. HYNES, M.R., DANG, H. & DUCKLES, S.P. (1988). Contractile responses to adrenergic nerve stimulation are enhanced with removal of endothelium in rat caudal artery. Life Sci., 42, 357-359.
19. IIMURA, O., KIRUCHI, K. & SATO, S. (1984). Plasma noradrenaline concentration and pressor response to infused noradrenaline in patients with borderline hypertension and mild or moderate essential hypertension. Jpn. Circ., 48, 159-167.
20. JONES, A.W., GEISBUHLER, B.B., SHUKLA, S.D. & SMITH, J.M. (1988). Altered biochemical and functional responses in aorta from hypertensive rats. Hypertension, 11, 627-634.
21. KATOVICH, M.J., SOLTIS, E.E., ILOEJE, E. & FIELD, F.D. (1984). Time course alterations in vascular adrenergic responsiveness in DOCA/NaCl treated rat. Pharmacology, 29, 173-180.
22. KAWAMURA, K., ANDO, K. & TAKEBAYASHI, S. (1989). Perivascular innervation of the mesenteric artery in spontaneously hypertensive rats. Hypertension, 14, 660-668.
23. KWAN, C.Y. & LEE, R.M.K.W. (1990). Changes of β-adrenoceptors in the aortic muscle cells of spontaneously hypertensive rats. Can. J. Physiol. Pharmacol., 68, 1461-1468.
24. MARİN, J. (1993). Mechanisms involved in the increased vascular resistance in hypertension. J. Auton. Pharmacol., 13, 127-176.
25. MEDGETT, I.C. & LANGER, S.Z. (1984). Heterogeneity of smooth muscle alpha adrenoceptors in rat tail artery in vitro. J. Pharmacol. Exp. Ther., 229, 823-830.
26. 3H-norepinephrine release in a caudal artery of spontaneously hypertensive and Wistar-Kyoto rats: effects of altered salt diets. Pharmacology, 44, 19-25.
27. MICHEI, M.C., BRODDE, O.E. & INSEL, P.A. (1990). Peripheral adrenergic receptors in hypertension. Hypertension, 16, 107-120.
28. MORIGUCHI, A., BROSNIHAN, K.B., KUMAGAI, H., GANTEN, D. & FERRARIO, C.M. (1994). Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene. Am. J. Physiol., 266, R1273-R1279.
29. MULLINS, J.J., PETERS, J. & GANTEN, D. (1990). Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature, 344, 541-544.
30. NIELSEN, K.C. & OWMAN, C. (1971). Contractile responses and amine receptor mechanisms in isolated middle cerebral artery of the cat. Brain Res., 27, 33-42.
31. OKAMURA, T., MIYAZAKI, M., INAGAMI, T. & TODA, N. (1986). Vascular renin-angiotensin system in two-kidney, one clip hypertensive rats. Hypertension, 8, 560-565.
32. PEIRO, C., DE SAGARRA, M.R., REDONDO, J., SANCHEZ-FERRER, C.F. & MARİN, J. (1992). Vascular smooth muscle proliferation in hypertensive transgenic rats. J. Cardiovasc. Pharmacol., 20(suppl 12), S128-S131.
33. 2-adrenoceptors. Eur. J. Pharmacol., 177, 35-41.
34. SEIDELIN, P.H., COLLIER, J.G., STRUTHERS, A.D. & WEBB, D.J. (1991). Angiotensin II augments sympathetically mediated arteriolar constriction in man. Clin. Sci., 81, 261-266.
35. SHEPHERD, J.T. (1990). Increased systemic vascular resistance and primary hypertension: the expanding complexity. J. Hypertens., 8(suppl 7), S15-S27.
36. SITTIRACHA, T. MCLACHAN, E.M. & BELL, C. (1987). The innervation of the caudal artery of the rat. Neuroscience, 21, 647-659.
37. SOH, K. (1987). Captopril attenuates the angiotensin I induced potentiation of the contractile responses to transmural nerve stimulation in the isolated rabbit pulmonary artery. Asia Pacif. J. Pharmacol., 2, 235-239.
38. SULPIZIO, A. & HIEBLE, J.P. (1991). Lack of pharmacological distinction between alpha-1 adrenoceptors mediating intracellular calcium-dependent and independent contractions to sympathetic nerve stimulation in the perfused rat caudal artery. J. Pharmacol. Exp. Ther., 257, 1045-1052.
39. SZABÓ, C.S. & HARDEBO, J.E. (1990). Characterization of a neurogenic and a direct smooth muscle component in the contractile response to electrical field stimulation in rat tail artery. J. Auton. Pharmacol., 10, 283-296.
40. TADDEI, S., FAVILLA, S., DURANTI, P., SIMONINI, N. & SALVETTI, A. (1991). Vascular renin-angiotensin system and neurotransmission in hypertensive persons. Hypertension, 18, 266-277.
41. TEMPLETON, A.G.B., MACMILLAN, J., MCGRATH, J.C., STORY, N.D. & WILSON, V.G. (1989). Evidence for prazosin-resistant, rawolscine-sensitive α-adrenoceptors mediating contractions in the isolated vascular bed of the rat tail. Br. J. Pharmacol., 97, 563-571.
42. 2-adrenoceptors in blood vessels: effect of age. Eur. J. Pharmacol., 237, 311-316.
43. VO, P.A., REID, J.J. & RAND, M.J. (1991). Endothelial nitric oxide attenuates vasoconstrictor responses to nerve stimulation and noradrenaline in the rat tail artery. Eur. J. Pharmacol., 199, 123-125.
44. WESTFALL, T.C., BADINO, L., NIES, L. & MELDRUM, M.J. (1987). Alterations in the field stimulation-induced release of endogenous norepinephrine from the coccigeal artery of spontaneously hypertensive and Wistar Kyoto rats. Eur. J. Pharmacol., 135, 433-437.
45. WYSE, G. (1977). Alteration of exogenous norepinephrine caused by electrical field stimulation and its role in poststimulant relaxation. Can. J. Physiol., Pharmacol., 55, 990-1000.