Hydride reagents for stereoselective reductive amination. An improved preparation of 3-endo-tropanamine

Tetrahedron Letters

Volumn 37, Issue 23, 1996, Pages 3977-3980

  McGill, John M ^a   Labell, Elizabeth S ^a   Williams, MaryAnn ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 TROPANAMINE; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0029897159     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00760-5     Document Type: Article

References (23)

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23. 4) and concentrated. The crude amine product was either hydrogenolyzed (5% Pd/C) to remove the benzyl group or isolated as an HCl salt by the addition of anhydrous HCl.