Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2-Deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonate and its analogs inhibit glycosylphosphatidylinositol phospholipase C

Journal of Biological Chemistry

Volumn 271, Issue 26, 1996, Pages 15468-15477

  Morris, James C ^a   Ping Sheng, Lei ^b   Zhai, Hai Xiao ^b   Shen, Tsung Ying ^b   Mensa Wilmot, Kojo ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CONCANAVALIN A; GENTAMICIN; GLYCOSYLPHOSPHATIDYLINOSITOL; KANAMYCIN A; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C;

ALLOSTERISM; ARTICLE; BACILLUS CEREUS; COMPETITIVE INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ANIMALS; ANTI-BACTERIAL AGENTS; BACILLUS CEREUS; BINDING, COMPETITIVE; CATTLE; CELLS, CULTURED; CONCANAVALIN A; ENZYME ACTIVATION; ENZYME INHIBITORS; GENTAMICINS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; INOSITOL; KINETICS; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C; PHOSPHONIC ACIDS; PHOSPHORIC DIESTER HYDROLASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

BACILLUS CEREUS; FELIS CATUS; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0029896753     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.26.15468     Document Type: Article

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