Stimulation of the T-Cell antigen receptor-CD3 complex signaling pathway by the tyrosine phosphatase inhibitor pervanadate is mediated by inhibition of CD45 evidence for two interconnected Lck/Fyn- Or Zap-70-dependent signaling pathways

Journal of Inflammation

Volumn 46, Issue 2, 1996, Pages 65-77

  Imbert, Véronique ^a   Farahifar, Dariush ^a   Auberger, Patrick ^b   Mary, Didier ^b   Rossi, Bernard ^a   Peyron, Jean François ^a  

^a INSERM   (France)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

CD45; Complex; Inhibition protein; Protein tyrosine phosphatase pervanadate; T cell antigen receptor cd3; Tyrosine kinase ick fyn zap 70

Indexed keywords

CD3 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN 2; PERVANADATE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; LEUKEMIA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SIGNAL PROCESSING; T LYMPHOCYTE;

ANTIGENS, CD3; ANTIGENS, CD45; BASE SEQUENCE; BINDING SITES; DNA; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-2; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN-TYROSINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; T-LYMPHOCYTES; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VANADATES; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0029896636     PISSN: 10787852     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Hsi ED, Siegel JN, Minami Y, Leuong ET, Klausner RD, Samelson LE: T cell activation induces rapid tyrosine phosphorylation of a limited number of cellular substrates. J Biol Chem 264: 10836-10842, 1989.
2. June CH, Fletcher MC, Ledbetter JA, Samelson LE: Increases in tyrosine phosphorylation are detectable before phospholipase C activation after! cell receptor stimulation. J Immunol 144: 1591-1599, 1990.
3. June CH, Fletcher MC, Ledbetter JA, Schieven GL, Philips AF, Samelson LE: Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction. Proc Natl Acad Sei USA 87: 7722-7726, 1990.
4. Mustelin T, Coggeshall KM, Isakov N, Altman A: T cell antigen receptor mediated activation of phopholipase requires tyrosine phosphorylation. Science 247: 15841587, 1990.
5. Clevers H, Alarcon B, Wileman T, Terhorst C: The T cell receptor/CD3: a dynamic protein ensemble. Ann Rev Immunol 6: 629-662, 1988.
6. Weiss A: T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases. Cell 73: 209-212, 1993.
7. Samelson LE, Philips AF, Luong ET, Klausner RD: Association of the fyn protein-tyrosine kinase with the Tcell antigen receptor. Proc Natl Acad Sei USA 87: 43584362, 1990.
8. Tsygankov AY, Broker BM, Fargnoli J, Ledbetter JA, Bolen, JB: Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking. J Biol Chem 267: 18259-18262, 1992.
9. Veillette A, Bookman MA, Horak E, Bolen JB: The CD4 and CDS T cell surface antigens are associated with the internal membrane tyrosine protein kinase p56'c. Cell 55: 301-308, 1988.
10. Barber EK, Dasgupta JD, Schlossman SF, Trevillyan JM, Rudd CE: The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56'c) that phosphorylates the CDS complex. Proc Natl Acad Sei USA 86: 32773281, 1989.
11. Strauss DB, Weiss A: Genetic evidence for the involvement of Ick tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 70: 585-593, 1992.
12. Chan AC, Irving BA, Fraser JD, Weiss A: The Çchain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation. Proc Natl Acad Sei USA 88: 9166-9170, 1991.
13. Chan AC, Iwashima M, Turck CW, Weiss A: ZAP-70: a 70kd protein-tyrosine kinase that associates with the TCR Çchain. Cell 71: 649-662, 1992.
14. Wange RL, Malek SN, Desiderio S, Samelson LE: Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor Çand CD3e from activated Jurkat T cells. J Biol Chem 268: 19797-19801, 1993.
15. Isakov N, Wange RL, Burgess WH, Watts JD, Aebersold R, Samelson LE: ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: The tandem SH2 domains of ZAP-70 bind distinct tyrosinebased activation motifs with varying affinity. J Exp Med 181: 375-380, 1994.
16. Trowbridge IS: CD45: a prototype for transmembrane protein tyrosine phosphatases. J Biol Chem 266: 2351723520, 1991.
17. Koretzky GA: Role of the CD45 tyrosine phosphatase in signal transduction in the immune system. FASEB J 7: 420-426, 1993.
18. Koretzky GA, Picus J, Thomas ML, Weiss A: Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway. Nature 346: 66-68, 1990.
19. Peyron J-F, Verma S, de Waal Malefyt R, Sancho J, Terhorst C, Spits H: The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat cell line. Int Immunol 3: 1357-1366, 1991.
20. Koretzky JA, Picus J, Schultz T, Weiss A: Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc Natl Acad Sei USA 88: 2037-2041, 1991.
21. O'Shea JJ, McVicar DW, Bailey TL, Burns C, Smyth MJ: Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phos-phorylation. Proc Natl Acad Sei USA 89: 10306-10310, 1992.
22. Pumiglia KM, Lau FF, Huang CK, Burroughs S, Feinstein MB: Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide). Biochem J 286: 441-449.
23. Grinstein S, Furuya W, Lu DJ, Mills GB: Vanadate stimulates oxygen consumption and tyrosine phosphorylation in electropermeabilized human neutrophils. J Biol Chem 265: 318-327, 1990.
24. Shisheva A, Shechter Y: Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes. J Biol Chem 268: 6463-6469, 1993.
25. Trudel S, Paquet MR, Grinstein S: Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites. Biochem J 276: 611-619, 1991.
26. Imbert V, Peyron J-F, Farahi Far D, Mari B, Auberger P, Rossi B: Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases. Biochem J 297: 163-173, 1994.
27. Secrist JP, Burns LA, Karnitz L, Koretzky GA, Abraham R: Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J Biol Chem 268: 5886-5893, 1993.
28. Bradford MM: A rapid method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72: 248-254, 1976.
29. Osborn l, Kunkel S, Nabel GJ: Tumor necrosis factor a and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor KB. Proc Natl Acad Sei USA 86: 2236-2240, 1989.
30. Dignam JD, Lebovits RM, Roeder RG: Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1479, 1983.
31. Cooke MP, Abraham KM, Forbush KA, Perlmutter RM: Regulation of T cell receptor signaling by a src family protein tyrosine kinase (p59fyn). Cell 65: 281-291, 1991.
32. Abraham N, Miceli MC, Parnes JR, Veillette A: Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine kinase p56'c. Nature 350: 62-66, 1991.
33. Weiss A, Koretzky G, Schatzman RC, Kadlecek T: Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase Cy1. Proc Natl Acad Sei USA 88: 5484-5488, 1991.
34. Ravichandran KS, Lee KK, Songyang Z, Cantley LC, Burn P, Burakoff S: Interaction of She with the Çchain of the T cell receptor upon T cell activation. Science 262: 902-905, 1993.
35. Gulbins E, Coggeshall KM, Baier G, Katzav S, Burn P, Altman A: Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation. Science 260: 822-825, 1993.
36. Crabtree GR, Clipstone NA: Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu Rev Biochem 63: 1045-1083, 1994.
37. Testi R, Philips JH, Lanier LL: Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. J Immunol 142: 1854-1860, 1989.
38. Waldmann TA: The IL-2/IL-2 receptor system: A target for rational immune intervention. Immunol Today 14: 264-270, 1993.
39. Deans JP, Kanner SB, Torres RM, Ledbetter JA: Interaction of CD4: Ick with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase. Eur J Immunol 22: 661-668, 1992.
40. Danielian S, Alcover A, Polissard L, Stefanescu M, Acuto 0, Fischer S, Fagard R: Both T cell receptor (TcR)-CDS complex and CD2 increase the tyrosine kinase activity of p56'c. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56'c. Eur J Immunol 22: 2915-2921, 1992.
41. Burkhardt AL, Stealey B, Rowley RB, Mahajan S, Prendergast M, Fargnoli J, Bolen JB: Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement. J Biol Chem 269: 23642-23647, 1994.
42. Iwashima M, Irving BA, van 0, NSC, Chan AC, Weiss A: Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263: 1136-1139, 1994.
43. Kolanus W, Romeo C, Seed B: T cell activation by clustered tyrosine kinases. Cell 74: 171-183, 1993.
44. Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo W-L, Iwashima M, Parslow TG, Weiss A: ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264: 1599-1601, 1994.
45. Niklinska BB, Yamada H, O'Shea JJ, June C II, Ashwell JO: Tyrosine-kinase regulated and inositol phosphateindependent Ca2+ elevation and mobilization in T cells. J Biol Chem 267: 7154-7159, 1992.
46. Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, Nicoletti I, Grignani F, Pawson T, Pelicci PG: A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell 70: 93-104, 1992.
47. Sloan-Lancaster J, Shaw AS, Rothbard JB, Allen PM: Partial T cell signaling: Altered phospho-C and lack of ZAP-70 recruitment in APL-induced T cell anergy. Cell 79: 913-922, 1994.
48. Madrenas J, Wange RL, Wang JL, Isakov N, Samelson LE, Germain RN: Çphosphorylation without ZAP-70 activation induced by TCR antagonists or partials agonists. Science 267: 515-518, 1995.
49. Wegener AMK, Letourneur F, Hoeveler A, Brocker T, Luton F, Malissen B: The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68: 83-95, 1992.
50. Letourneur F, Klausner RD: Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CDS e. Science 255: 79-82, 1992.
51. Malissen B, Schmitt-Verhuslt A-M: Transmembrane signalling through the T-cell-receptor-CD3 complex. Current Opi Immunol 5: 324-333, 1993.