Establishment of a clonal cell line producing granulocyte colony-stimulating factor and parathyroid hormone-related protein from a lung cancer patient with leukocytosis and hypercalcemia

Japanese Journal of Cancer Research

Volumn 87, Issue 5, 1996, Pages 451-458

  Asahi, Yasutomo ^a   Kubonishi, Ichiro ^a   Imamura, Jun ^a   Kamioka, Mikio ^a   Matsushita, Hiroshi ^b   Furihata, Mutsuo ^a   Ohtsuki, Yuji ^a   Miyoshi, Isao ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b TORANOMON HOSPITAL   (Japan)

Author keywords

Cell line; G CSF; Lung cancer; PTHrP; Squamous cell carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; MESSENGER RNA; PARATHYROID HORMONE RELATED PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CANCER TRANSPLANTATION; CELL CLONE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCALCEMIA; IMMUNOHISTOCHEMISTRY; LEUKOCYTOSIS; LUNG CANCER; MALE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TRANSCRIPTION REGULATION;

EID: 0029896556     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb00245.x     Document Type: Article

References (44)

1. Saito, K., Kuratomi, Y., Yamamoto, K., Saito, T., Kuzuya, T., Yoshida, S., Moriyama, S. and Takahashi, A. Primary squamous cell carcinoma of the thyroid associated with marked leukocytosis and hypercalcemia. Cancer, 48, 2080-2083 (1981).
2. Strewler, G. J., Williams, R. D. and Nissenson, R. A. Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors. J. Clin. Invest., 71, 769-774 (1983).
3. Kondo, Y., Sato, K., Ohkawa, H., Ueyama, Y., Okabe, T., Sato, N., Asano, S., Mori, M., Ohsawa, N. and Kosaka, K. Association of hypercalcemia with tumors producing colony-stimulating factor(s). Cancer Res., 43, 2368-2374 (1983).
4. Riddle, P. E. and Dincsoy, H. P. Primary squamous cell carcinoma of the thyroid associated with leukocytosis and hypercalcemia. Arch. Pathol. Lab. Med., 111, 373-374 (1987).
5. Sato, K., Fujii, Y., Kakiuchi, T., Kasono, K., Imamura, H., Kondo, Y., Mano, H., Okabe, T., Asano, S., Takaku, F., Tsushima, T. and Shizume, K. Paraneoplastic syndrome of hypercalcemia and leukocytosis caused by squamous carcinoma cells (T3M-1) producing parathyroid hormone related protein, interleukin 1α, and granulocyte colony-stimulating factor. Cancer Res., 49, 4740-4746 (1989).
6. Rizzoli, R., Sappino, A. P. and Bonjour, J.-P. Parathyroid hormone-related protein and hypercalcemia in pancreatic neuro-endocrine tumors. Int. J. Cancer, 46, 394-398 (1990).
7. Iguchi, H., Katakami, H., Ichinose, Y., Nishi, Y., Tanaka, S., Hara, N., Ohta, M., Haji, M. and Nawata, H. A case of squamous cell lung carcinoma with high concentration of parathyroid hormone-related peptide in serum and pleural effusion presenting hypercalcemia. Jpn. J. Cancer Res., 84, 419-424 (1993).
8. Matsuoka, S., Miura, Y., Kachi, T., Hattori, Y., Ohno, J., Oda, K., Nagamura, Y. and Oiso, Y. Humoral hypercalcemia of malignancy associated with parathyroid hormone-related protein producing transitional cell carcinoma of the ureter. Intern. Med., 33, 107-109 (1994).
9. Yoneda, T., Nishimura, R., Kato, I., Ohmae, M., Takita, M. and Sakuda, M. Frequency of the hypercalcemia-leukocytosis syndrome in oral malignancies. Cancer, 68, 617-622 (1991).
10. Asano, S., Urabe, A., Okabe, T., Sato, N., Kondo, Y., Ueyama, Y., Chiba, S., Ohsawa, N. and Kosaka, K. Demonstration of granulopoietic factor(s) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue. Blood, 49, 845-852 (1977).
11. Okabe, T., Sato, N., Kondo, Y., Asano, S., Ohsawa, N., Kosaka, K. and Ueyama, Y. Establishment and characterization of a human cancer cell line that produces human colony-stimulating factor. Cancer Res., 38, 3910-3917 (1978).
12. Suva, L. J., Winslow, G. A., Wettenhall, R. E. H., Hammonds, R. G., Moseley, J. M., Diefenbach-Jagger, H., Rodda, C. P., Kemp, B. E., Rodriguez, H., Chen, E. Y., Hudson, P. J., Martin, T. J. and Wood, W. I. A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression. Science, 237, 893-896 (1987).
13. Mangin, M., Webb, A. C., Dreyer, B. E., Posillico, J. T., Ikeda, K., Weir, E., Stewart, A. F., Bander, N. H., Milstone, L., Barton, D. E., Francke, U. and Broadus, A. E. Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy. Proc. Natl. Acad. Sci. USA, 85, 597-601 (1988).
14. Burtis, W. J., Brady, T. G., Orloff, J. J., Ersbak, J. B., Warrell, R. P., Olson, B. R., Wu, T. L., Mitnick, M. E., Broadus, A. E. and Stewart, A. F. Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of cancer. N. Engl. J. Med., 322, 1106-1112 (1990).
15. Ueyama, Y. and Tamaoki, N. Leukocytosis in nude mice into which human tumors are transplanted - in vivo screening system for hematopoietic growth factors in human tumors. In "Hematopoietic Growth Factors: Molecular Biology to Clinical Applications of rG-CSF," ed. P. J. Quesenberry, S. Asano and S. Saito, pp. 27-53 (1991). Excerpta Medica, Tokyo.
16. Ellison, M., Woodhouse, D., Hillyard, C., Dowsett, M., Coombes, R. C., Gilby, E. D., Greenberg, P. B. and Neville, A. M. Immunoreactive calcitonin production by human lung carcinoma cells in culture. Br. J. Cancer, 32, 373-379 (1975).
17. Rodan, S. B., Wesolowski, G., Ianacone, J., Thiede, M. A. and Rodan, G. A. Production of parathyroid hormone-like peptide in a human osteosarcoma cell line: stimulation by phorbol esters and epidermal growth factor. J. Endocrinol., 122, 219-227 (1989).
18. Ichinose, Y., Iguchi, H., Ohta, M. and Katakami, H. Establishment of lung cancer cell line producing parathyroid hormone-related protein. Cancer Lett., 74, 119-124 (1993).
19. Kinoshita, T., Imamura, J., Nagai, H. and Shimotono, K. Quantification of gene expression over a wide range by the polymerase chain reaction. Ann. Biochem., 206, 231-235 (1992).
20. Metcalf, D. and Nicola, N. A. Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hemopoietic cells. J. Cell. Physiol., 116, 198-206 (1983).
21. Nagata, S., Tsuchiya, M., Asano, S., Kaziro, Y., Yamazaki, T., Yamamoto, O., Hirata, Y., Kubota, N., Oheda, M., Nomura, H. and Ono, M. Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor. Nature, 319, 415-418 (1986).
22. Demetri, G. D. and Griffin, J. D. Granulocyte colony-stimulating factor and its receptor. Blood, 78, 2791-2808 (1991).
23. Moseley, J. M., Kubota, M., Diefenbach-Jagger, H., Wettenhall, R. E. H., Kemp, B. E., Suva, L. J., Rodda, C. P., Ebeling, P. R., Hudson, P. J., Zajac, J. D. and Martin, T. J. Parathyroid hormone-related protein purified from a human lung cancer cell line. Proc. Natl. Acad. Sci. USA, 84, 5048-5052 (1987).
24. Ikeda, K., Mangin, M., Dreyer, B. E., Webb, A. C., Posillico, J. T., Stewart, A. F., Bander, N. H., Weir, E. C., Insogna, K. L. and Broadus, A. E. Identification of transcripts encoding a parathyroid hormone-like peptide in messenger RNAs from a variety of human and animal tumors associated with humoral hypercalcemia of malignancy. J. Clin. Invest., 81, 2010-2014 (1988).
25. Enomoto, T., Sugawa, H., Inoue, D., Miyamoto, M., Kosugi, S., Takahashi, T., Kitamura, N., Yamamoto, I., Konishi, J., Mori, T. and Imura, H. Establishment of a human undifferentiated thyroid cancer cell line producing several growth factors and cytokines. Cancer, 65, 1971-1979 (1990).
26. Ikeda, K., Lu, C., Weir, E. C., Mangin, M. and Broadus, A. E. Transcriptional regulation of the parathyroid hormone-related peptide gene by glucocorticoids and vitamin D in a human C-cell line. J. Biol. Chem., 264, 15743-15746 (1989).
27. Merryman, J. I., Capen, C. C., McCauley, L. K., Werkmeister, J. R., Suter, M. M. and Rosol, T. J. Regulation of parathyroid hormone-related protein production by a squamous carcinoma cell line in vitro. Lab. Invest., 69, 347-354 (1993).
28. Binstock, M. L. and Mundy, G. R. Effect of calcitonin and glucocorticoids in combination on the hypercalcemia of malignancy. Ann. Intern. Med., 93, 269-272 (1980).
29. Merendino, J. J., Insogna, K. L., Milstone, L. M., Broadus, A. E. and Stewart, A. F. A parathyroid hormone-like protein from cultured human keratinocytes. Science, 231, 388-390 (1986).
30. Fried, R. M., Voelkel, E. F., Rice, R. H., Levine, L. and Tashjian, A. H. Evidence for multiple bone resorption-stimulating factors produced by normal human keratinocytes in culture. Endocrinology, 122, 2467-2475 (1988).
31. Chodakewitz, J. A., Kupper, T. S. and Coleman, D. L. Keratinocyte-derived granulocyte/macrophage colony-stimulating factor induces DNA synthesis by peritoneal macrophages. J. Immunol., 140, 832-836 (1988).
32. Demetri, G. D., Zenzie, B. W., Rheinwald, J. G. and Griffin, J. D. Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood, 74, 940-946 (1989).
33. Demetri, G. D., Ernst, T. J., Pratt, E. S., II, Zenzie, B. W., Rheinwald, J. G. and Griffin, J. D. Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes. J. Clin. Invest., 86, 1261-1269 (1990).
34. Li, X. and Drucker, D. J. Parathyroid hormone-related peptide is a downstream target for ras and src activation. J. Biol. Chem., 269, 6263-6266 (1994).
35. Simmers, R. N., Webber, L. M., Shannon, M. F., Garson, O. M., Wong, G., Vadas, M. A. and Sutherland, G. R. Localization of the G-CSF gene on chromosome 17 proximal to the breakpoint in the t(15;17) in acute promyelocytic leukemia. Blood, 70, 330-332 (1987).
36. Chang, J. M., Metcalf, D., Gonda, T. J. and Johnson, G. R. Long-term exposure to retrovirally expressed granulocyte-colony-stimulating factor induces a nonneoplastic granulocytic and progenitor cell hyperplasia without tissue damage in mice. J. Clin. Invest., 84, 1488-1496 (1989).
37. Keller, P. and Smalling, R. Granulocyte colony stimulating factor: animal studies for risk assessment. Int. Rev. Exp. Pathol., 34A, 173-188 (1993).
38. Vernant, J. P., Brun, B., Mannoni, P. and Dreyfus, B. Respiratory distress of hyperleukocytic granulocytic leukemias. Cancer, 44, 264-268 (1979).
39. Lester, T. J., Johnson, J. W. and Cuttner, J. Pulmonary leukostasis as the single worst prognostic factor in patients with acute myelocytic leukemia and hyperleukocytosis. Am. J. Med., 79, 43-48 (1985).
40. van Buchem, M. A., Colly, L. P., Hogendoorn, P. C. W., Kluin, P. M. and Willemze, R. Experimental myelocytic leukemia in the brown-Norway rat as a model for pulmonary leukostasis. Am. J. Pathol., 138, 777-780 (1991).
41. Vosburgh, E. Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse. Leukemia, 6, 608-610 (1992).
42. Tallman, M. S. and Kwaan, H. C. Reassessing the hemostatic disorder associated with acute promyelocytic leukemia. Blood, 79, 543-553 (1992).
43. Frankel, S. R., Eardley, A., Lauwers, G., Weiss, M. and Warrell, R. P., Jr. The "retinoic acid syndrome" in acute promyelocytic leukemia. Ann. Intern. Med., 117, 292-296 (1992).
44. Oeda, E., Shinohara, K., Kamei, S., Nomiyama, J. and Inoue, H. Capillary leak syndrome likely the result of granulocyte colony-stimulating factor after high-dose chemotherapy. Intern. Med., 33, 115-119 (1994).