No Differences in Mucosal Adaptive Growth One Week after Intestinal Resection in Rats Given Enteral Glutamine Supplementation or Deprived of Glutamine

European Journal of Surgery

Volumn 162, Issue 6, 1996, Pages 489-498

  Wirén, Mikael E ^a,b   Permert, Johan ^a   Skullman, Stefan P ^a   Wang, Feng ^a   Larsson, Jörgen ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

3H Thymidine; Amino acids; DNA; Polyamines; Proliferation; Small intestine; Transection

Indexed keywords

AMINO ACID; DNA; GLUTAMINE; POLYAMINE; THYMIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENTERIC FEEDING; FOOD DEPRIVATION; INTESTINE ADAPTATION; INTESTINE RESECTION; NONHUMAN; NUTRITIONAL SUPPORT; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SMALL INTESTINE MUCOSA;

ADAPTATION, PHYSIOLOGICAL; ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; CELL DIVISION; DNA; GLUTAMINE; ILEUM; INTESTINAL MUCOSA; INTESTINE, SMALL; JEJUNUM; MALE; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; THYMIDINE; TIME FACTORS;

EID: 0029896414     PISSN: 11024151     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Bontemps J, Laschet J, Dandrifosse G. Analysis of dansyl derivatives of di- and polyamines in mouse brain, human serum and duodenal biopsy specimens by high-performance liquid chromatography on a standard reversed-phase column. J Chromatog 1984; 311: 59-67.
2. Bristol JB, Williamson RCN. Nutrition, operations and intestinal adaptation. JPEN 1988; 12: 299-309.
3. Chen KY, Canellakis ES. Enzyme regulation in neuroblastoma cells in a salts/glucos medium: induction of ornithine decarboxylase by asparagine and glutamine. Proc Natl Acad Sci 1977; 74: 3791-3795.
4. Deutz NE, Dejong CH, Athanasas G, Soeters PB. Partial enterectomy in the rat does not diminish muscle glutamine production. Metabolism 1992; 41: 1343-1350.
5. Dowling RH, Hosomi M, Stace NH et al. Hormones and polyamines in intestinal and pancreatic adaptation. Scand J Gastroenterol 1985; Suppl 112: 84-95.
6. Dowling RH. Small bowel adaptation and its regulation. Scand J Gastroenterol 1982; 74: 53-76.
7. Fitzpatrick LR, Wang P, Eikenburg BE, Haddox MK, Johnson LR. Effect of refeeding on polyamine biosynthesis in isolated enterocytes. Am J Physiol 1986; 250: G709-G713.
8. Frankel WL, Zhang W, Afonso J et al. Glutamine enhancement of structure and function in transplanted small intestine in the rat. JPEN 1993; 17: 47-55.
9. Gouttebel MC, Astre C, Briand D, Saint-Aubert B, Girardot PM, Joyeux H. Influence of N-acetylglutamine or glutamine infusion on plasma amino acid concentrations during the early phase of small-bowel adaptation in the dog. JPEN 1992; 16: 117-121.
10. Gouttebel MC, Girardot PM, Saint-Aubert B, Joyeux H. Clinical, biological and histological follow-up during intestinal adaptation after small bowel resection in the dog. Eur Surg Res 1991; 23: 333-340.
11. Hansson WR, Osborne JW, Sharp JG. Compensation by the residual intestine after intestinal resection in the rat - influence of postoperative time interval. Gastroenterology 1977; 72: 701-705.
12. Jacobs DO, Evans DA, Mealy K, O'Dwyer ST, Smith RJ, Wilmore DW. Combined effects of glutamine and epidermal growth factor on the rat intestine. Surgery 1988; 104: 358-364.
13. Klimberg VS, Souba WW, Salloum RM et al. Intestinal glutamine metabolism after massive small bowel resection. Am J Surg 1990; 159: 27-33.
14. Koruda MJ, Rolandelli R, Settle RG. Saul SH, Rombeau JL. The effect of a pectin-supplemented elemental diet on intestinal adaptation to massive small bowel resection. JPEN 1986; 10: 343-350.
15. Labarca C, Paigen K. A simple rapid and sensitive DNA assay procedure. Anal Biochem 1980; 102: 344-352.
16. Livstone EM, Tilson MD. Autoradiographic measurement of early proliferative changes after small bowel resection. Gastroenterology 1975; 68: 937.
17. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265-275.
18. Luk GD, Baylin SB. Polyamines and intestinal growth - increased polyamine biosynthesis after jejunectomy. Am J Physiol 1983; 245: G656-G660.
19. Luk GD, Baylin SB. Inhibition of intestinal epithelial DNA synthesis and adaptive hyperplasia after jejunectomy in the rat by suppression of polyamine biosynthesis. J Clin Invest 1984; 74: 698-704.
20. Luk GD, Yang P. Distribution of polyamines and their biosynthetic enzymes in intestinal adaptation. Am J Physiol 1988: 254: G194-G200.
21. Obertop H, Nundy S, Nalamud D, Malt RA. Onset of cell proliferation in the shortened gut - rapid hyperplasia after jejunal resection. Gastroenterology 1977; 72: 267-270.
22. Pegg AE, McCann PP. Polyamine metabolism and function. Am J Physiol 1982; 243: C212-C221.
23. Riecken EO, Stallmach A, Zeitz M, Schulzke JD, Menge H, Gregor M. Growth and transformation of the small intestinal mucosa - importance of connective tissue, gut associated lymphatic tissue and gastrointestinal regulatory peptides. Gut 1989; 30: 1630-1640.
24. Rinehart CA, Canellakis ES. Induction of ornithine decarboxylase activity by insulin and growth factors is mediated by amino acids. Proc Natl Acad Sci USA 1985; 82: 4365-4368.
25. Rinehart CA, Viceps-Madore D, Fong WF, Ortiz JG, Canellakis ES. The effect of transport system A and N amino acid and of nerve and epidermal growth factors on the induction of ornithine decarboxylas activity. J Cell Physiol 1985; 123: 435-441.
26. Sepulveda FV, Burton KA, Clarksson GM, Syme G. Cell differentiation and l-ornithine decarboxylase activity in the small intestine of rats fed low and high protein diets. Biochim Biophys Acta 1982; 716: 439-442.
27. Smith RJ, Wang XD, Wilmore DW. Glutamine enhances intestinal adaptation following massive small bowel resection. Clin Res 1988; 36: 359A.
28. Souba WW, Herskowitz K, Austgen TR, Chen MK, Salloum RM. Glutamine nutrition: theoretical considerations and therapeutic impact. JPEN 1990; 14: 237S-243S.
29. Sumikawa M, Nishimura O, Koga S. The effects of diet on the residual small intestine following massive resection. Japn J Surg 1988; 18: 308-315.
30. Tabata K, Johnson LR. Ornithine decarboxylase and mucosal growth in response to feeding. Am J Physiol 1986; 251: G270-G274.
31. Tamada H, Nezu R, Matsuo Y, Imamura I, Takagi Y, Okada A. Alanyl Glutamine-enriched total parenteral nutrition restores intestinal adaptation after either proximal or distal massive resection in rats. JPEN 1993; 17: 236-242.
32. Tilson MD. Pathophysiology and treatment of short bowel syndrome. Surg Clin North Am 1980; 60: 1273-1284.
33. Vanderhoof JA, Blackwood DJ, Mohammadpour H, Park JH. Effects of oral supplementation of glutamine on small intestinal mucosal mass following resection. J Am Coll Nutr 1992; 11: 223-227.
34. Vanderhoof JA. Regulatory peptides and intestinal growth. Gastroenterology 1993; 104: 1205-1208.
35. Williamson RCN. Intestinal adaptation. Structural, functional and cytokinetic changes. N Engl J Med 1978; 298: 1393-1402.
36. Williamson RCN. Intestinal adaptation. Mechanisms of control. N Engl J Med 1978; 298: 1444-1450.
37. Wirén M, Permert J, Skullman S, Wang F, Larsson J. Intraluminal glutamine refeeding supports mucosal growth in rat jejunum. Transplant Proc 1994; 26: 1460-1463.