The human mammary-derived growth inhibitor (MDGI) gene: Genomic structure and mutation analysis in human breast tumors

Genomics

Volumn 34, Issue 1, 1996, Pages 63-68

  Phelan, Catherine M ^a,b   Larsson, Catharina ^a   Baird, Stephen ^c   Futreal, P Andrew ^d   Ruttledge, M H ^g   Morgan, Kenneth ^b   Tonin, Patricia ^b   Hung, Huynh ^e   Korneluk, Robert G ^c   Pollak, Michael N ^e,f   Narod, Steven A ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f MCGILL UNIVERSITY   (Canada)

^g Montreal General Hospital ^*

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GENE PRODUCT; GROWTH INHIBITOR; LYSINE;

ADULT; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER CELL CULTURE; CHROMOSOME 1P; CHROMOSOME MAP; CLINICAL ARTICLE; CONTROLLED STUDY; EXON; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC POLYMORPHISM; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

MUS MUSCULUS;

EID: 0029896288     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0241     Document Type: Article

References (29)

1. Bieche, I., Champene, M., and Lidereau, R. (1994). A tumour suppressor gene on chromosome 1p32-pter controls the amplification of myc family genes in breast cancer. Cancer Res. 54: 4274-4276.
2. Bieche, I., Champene, M., Matifas, F., Cropp, C., Callehan, R., and Lidereau, R. (1993). Two distinct regions involved in 1p deletion in human primary breast cancer. Cancer Res. 53: 1990-1994.
3. Böhmer, F., Kraft, R., Otto, A., Wernstedt, C., Hellman, U., Kurtz, A., Muller, T., Rodhe, K., Etzold, G., Lehmann, W., Langen, P., Heldin, C., and Grosse, R. (1987). Identification of a polypeptide growth inhibitor from bovine mammary gland. J. Biol. Chem. 262: 15137-15143.
4. Borg, A., Zhang, Q.-X., Olsson, H., and Wenngren, E. (1992). Chromosome 1 alterations in breast cancer: Allelic loss on 1p and 1q is related to lymphogenic metastases and poor prognosis. Genes Chromosomes Cancer 5: 311-320.
5. Callahan, R., Cropp, C., Merlo, G., Liscia, D., Cappa, A., and Lidereau, R. (1992). Somatic mutations and human breast cancer: A status report. Cancer 69: 1582-1588.
6. Chen, E., Schlessinger, D., and Kere, J. (1993). Ordered shotgun sequencing, a strategy for integrated mapping and sequencing of YAC clones. Genomics 17: 651-656.
7. Dear, S., and Staden, R. (1991). A sequence assembly and editing program for efficient management of large projects. Nucleic Acids Res. 19: 3907-3911.
8. Futreal, P., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L., Haugen-Strano, A., Swensen, J., Miki, Y., Eddington, K., McLure, M., Frye, C., Weaver-Feldhaus, J., Ding, W., Gholami, Z., Söderkvist, P., Terry, L., Jhanwar, S., Berchuck, A., Iglehart, J., Marks, J. D. G., Barrett, J., Skolnick, M., Kamb, A., and Wiseman, R. (1994). BRCA1 mutations in primary breast and ovarian carcinomas. Science 266: 120-122.
9. Futreal, P., Soderkvist, P., Marks, J., Iglehart, J., Cochran, C., Barrett, J., and Wiseman, R. (1992). Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res. 52: 2624-2627.
10. Gleeson, R., and Hiller, L. (1991). A trace display and editing program for data from fluorescence based sequencing machines. Nucleic Acids Res. 19: 6491-6493.
11. Grosse, R., Böhmer, F.-D., Binas, B., Kurtz, A., Spitzer, E., Muller, T., and Zschiesche, W. (1991). Mammary-derived growth inhibitor (MDGI). In "Genes, Oncogenes and Hormones: Advances in Cellular and Molecular Biology of Breast Cancer" (R. B. D. a. M. E. Lippman, Ed.), pp. 69-96, Kluwer Academic, Boston.
12. Gyapay, G., Morisette, J., Vignal, A., Dib, C., Fizames, C., Millasseau, P., Marc, Bernardi, G., Lathrop, M., and Weissenbach, J. (1994). The 1993-94 Généthon human genetic linkage map. Nature Genet. 7: 246-339.
13. Herman, J., Latif, F., Weng, Y., Lerman, M., Zbar, B., Liu, S., and Samid, D. (1994). Silencing of the VHL tumour suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. USA 91: 9700-9704.
14. Hoggard, N., Brintnell, B., Howell, A., Weissenbach, J., and Varley, J. (1995). Allelic imbalance on chromosome 1 in human breast cancer. II. Microsatellite repeat analysis. Genes Chromosomes Cancer 12: 24-31.
15. Hung, H., Larsson, C., Narod, S., and Pollak, M. (1995). Tumour suppressor activity of the gene encoding mammary-derived growth inhibitor. Cancer Res. 55: 2225-2231.
16. Hutter, R. (1987). Worldwide agreement on the staging of cancer. Arch. Surgery 122: 1235-1246.
17. Knudson, A. (1993). Antioncogenes and human cancer. Proc. Natl. Acad. Sci. USA 90: 10914-10921.
18. Larsson, C., Byström, C., Skoog, L., Rotstein, S., and Nordenskjöld, M. (1990). Genomic alterations in human breast carcinomas. Genes Chromosomes Cancer 2: 191-197.
19. Munn, K., Walker, R., and Varley, J. (1995). Frequent alterations of chromosome 1 in ductal carcinoma in situ of the breast. Oncogene 10: 1653-1657.
20. Offner, G., Brecher, P., Sawlivich, W., Costello, C., and Troxler, R. (1988). Characterization and amino acid sequence of a fatty acid-binding protein from human heart. Biochem. J. 252: 191-198.
21. Ohtani-Fujita, N., Fujita, T., Aoike, A., Osifchin, N., Robbins, P., and Sakai, T. (1993). CpG methylation inactivates the promoter activity of the human retinoblastoma tumour suppressor gene. Oncogene 8: 1063-1067.
22. Peeters, R., Veerkamp, J., van Kessel, A., Kanda, T., and Ono, T. (1991). Cloning of the cDNA encoding human skeletal-muscle fatty-acid binding protein, it's peptide sequence and chromosomal localization. Biochem. J. 276: 203-207.
23. Phelan, C., Liu, L., Ruttledge, M., Müntzning, K., Ridderheim, P.-Å., and Collins, V. (1995). Chromosome 17 abnormalities and lack of TP53 mutations in paediatric central nervous system tumours. Hum. Genet. 96: 684-690.
24. Ruttledge, M., Sarrazin, J., Rangaratnam, S., Phelan, C., Twist, E., Merel, P., Delattre, O., Thomas, G., Nordenskjöld, M., Collins, V., Dumanski, J., and Rouleau, G. (1994). Evidence for the complete inactivation of the neurofibromatosis type 2 gene in the majority of sporadic mengiomas. Nature Genet. 6: 180-184.
25. Spener, F., Unterberg, C., Börchers, T., and Grosse, R. (1990). Characteristics of fatty acid-binding proteins and their relation to mammary-derived growth inhibitor. Mol. Cell. Biochem. 98: 57-68.
26. Thompson, M., Jensen, R., Obermiller, P., Page, D., and Holt, J. (1995). Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nature Genet. 9: 444-450.
27. Treuner, M., Kozak, C., Gallahan, D., Grosse, R., and Muller, T. (1994). Cloning and characterization of the mouse gene encoding mammary-derived growth inhibitor/heart-fatty acid-binding protein. Gene 147: 237-242.
28. Troxler, R., Offner, G., Jiang, J., Wu, B., Skare, J., Milunsky, A., and Wyandt, H. (1993). Localization of the gene for human heart fatty acid binding protein to chromosome 1p32-1p33. Hum. Genet. 92: 563-566.
29. Yang, Y., Spitzer, E., Kenney, N., Zschiesche, W., Li, M., Kromminga, A., Muller, T., Spener, F., Lezius, A., Veerkamp, J., Smith, G., Salomon, D., and Grosse, R. (1994). Members of the fatty acid binding protein family are differentiation factors for the mammary gland. J. Cell Biol. 124: 1097-1109.