Insulin-like growth factor I alters peripheral thyroid hormone metabolism in humans: Comparison with growth hormone

European Journal of Endocrinology

Volumn 134, Issue 5, 1996, Pages 563-567

  Hussain, Mehboob A ^a   Schmitz, Ole ^b   Jorgensen, Jens O L ^b   Christiansen, Jens S ^b   Weeke, Jorgen ^b   Schmid, Christoph ^a   Froesch, E Rudolf ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; LEVOTHYROXINE; LEVOTHYROXINE SODIUM; LIOTHYRONINE; SOMATOMEDIN C; THYROXINE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEMALE; GROWTH HORMONE DEFICIENCY; HUMAN; HYPOPHYSIS DISEASE; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; THYROID HORMONE METABOLISM;

EID: 0029896054     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1340563     Document Type: Article

References (24)

1. Grunfeld C, Sherman BM, Cavalieri RR. The acute effects of human growth hormone administration on thyroid function in normal men. J Clin Endocrinol Metab 1988;67:1111-4
2. Schwander JC, Hauri C, Zapf J, Froesch ER. Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology 1983;113:297-305
3. Froesch ER, Guler HP, Schmid C, Ernst M, Zapf J. Insulin-like growth factors. In: Rifkin H, Porte D, editors. Ellenberg and Rifkins's diabetes mellitus. Theory and practice. 4th ed, Ch. 9, New York: Elsevier, 1990:154-69
4. Hussain MA, Schmitz O, Mengel A, Keller A, Christiansen JS, Zapf J, et al. Comparison of the effects of growth hormone and insulin-like growth factor-I in growth hormone-deficient subjects. J Clin Invest 1994;94:1126-33
5. Hoffmann DM, O'Sullivan AJ, Baxter RC, Ho KK. Diagnosis of growth-hormone deficiency in adults. Lancet 1994;343:1064-8
6. Weeke J, Gundersen HJG. Circadian and 30-min variations in serum TSH and thyroid hormones in normal subjects. Acta Endocrinol (Copenh) 1978;89:659-72
7. Weeke J, Orskov H. Ultrasensitive radioimmunoassay for direct determination of free triiodothyronine concentration in serum. Scand J Clin Lab Invest 1975;35:237-44
8. Weeke J, Orskov H. In: Alberti KGMM editor. Recent advances in clinical biochemistry, vol 1. Edinburgh: Churchill Livingstone, 1978:111-8
9. Hussain MA, Schmitz O, Mengel A, Keller A, Christiansen JS, Zapf J, et al. Insulin-like growth factor I stimulates lipid oxidation, reduces protein oxidation, and improves insulin sensitivity in humans. J Clin Invest 1993;92:2249-56
10. Moller J, Jorgensen JOL, Moller N, Christiansen JS, Weeke J. Effects of growth hormone administration on fuel oxidation and thyroid function in normal man. Metabolism 1992;41:728-31
11. Salomon F, Cuneo RC, Hesp R, Sönksen P. The effect of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989;321:1797-803
12. Ho KY, Weissberger AJ, Stuart MC. The pharmacokinetics, safety, and endocrine effects of authentic biosynthetic human growth hormone in normal subjects. Clin Endocrinol 1989;30:335-45
13. Jorgensen JOL, Pedersen SA, Laurberg P, Weeke J, Skakkebaek NE, Christiansen JS. Effects of growth hormone therapy in thyroid function of growth hormone-deficient adults with and without concomitant thyroxine-substituted central hypothyroidism. J Clin Endocrinol Metab 1989;69:1127-32
14. Klinger B, Ionesco A, Anin S, Laron Z. Effects of insulin-like growth factor I on the thyroid axis in patients with Laron-type dwarfism and healthy subjects. Acta Endocrinol 1992;127:515-9
15. Chopra I. In: Braverman LE, Utiger RD, editors. Werner and Ingbar's. The thyroid. A fundamental and clinical text. 6th ed. Philadelphia: JB Lippincott, 1986:126-43
16. Caro JF, Poulos J, Ittoop O, Portes WJ, Flickinger EG, Sinha K. Insulin-like growth factor-I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal liver. J Clin Invest 1988;81:976-81
17. Bermgann M, Jaffe CA, Tsai W, DeMott-Friberg R, Barkan A. Negative feedback regulation of pulsatile growth hormone secretion by insulin-like growth factor-I. Involvement of hypothalamic somatostatin. J Clin Invest 1994;94:138-45
18. Vanelli GB, Barni T, Modigliani U, Paulin I, Serio M, Maggi M, et al. Insulin-like growth factor-I receptors in nonfunctioning thyroid nodules. J Clin Endocrinol Metab 1990;71:1175-82
19. 2+ influx induced by a combination of thyrotropin and insulin-like growth factor-I in rat thyroid cells. J Clin Invest 1990;86:1548-55
20. Takahashi S, Conti M, Van-Wyk JJ. Thyrotropin potentiation of insulin-like growth factor-I dependent deoxyribonucleic acid synthesis in FRTL-5 cells: mediation by an autocrine amplification factor(s). Endocrinology 1990;126:736-45
21. Santini F, Chiovato L, Lapi P, Lupetti M, Dolfi A, Bianchi F, et al. The location and the regulation of the type I-iodothyronine 5′ monodeiodase (type I-MD) in the rat thyroid: studies using a specific anti-type I-MD antibody. Mol Cell Endocrinol 1995;110:195-203
22. Brenner-Gati L, Berg KA, Gershegorn MC. Insulin-like growth factor-I potentiates thyrotropin stimulation of adenylcyclase in FTRL-5 cells. Endocrinology 1989;125:1315-20
23. Tode B, Serio M, Rotella CM, Galli G, Franchiselli F, Tanini A, et al. Insulin-like growth factor-1: autocrine secretion by human thyroid follicular cells in primary culture. J Clin Endocrinol Metab 1989;69:639-47
24. Yoshinari M, Tokuyama T, Kuroda T, Sato K, Okazawa K, Mizokami T, et al. Preserved thyroidal secretion of thyroxine in acromegalic patients with suppressed hypophyseal secretion of thyrotropin. Clin Endocrinol Oxf 1992;36:355-60