Torreyanic acid: A selectively cytotoxic quinone dimer from the endophytic fungus Pestalotiopsis microspora

Journal of Organic Chemistry

Volumn 61, Issue 10, 1996, Pages 3232-3233

  Lee, Julie C ^a   Strobel, Gary A ^b   Lobkovsky, Emil ^a   Clardy, Jon ^a  

^a Department of Molecular Biology and Genetics   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC AGENT; PROTEIN KINASE C; TORREYAMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; FUNGUS; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE; TUMOR CELL;

EID: 0029895763     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo960471x     Document Type: Article

References (7)

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5. Lee, J. C.; Yang, X.; Schwartz, M.; Strobel, G.; Clardy, J. Chem. Biol. 1995, 2, 721-727
6. Crystals of 1 form in the monoclinic space group C2 with α = 25.273(6), b = 11.634(3), and c = 13.073 Å and β = 100.41(2)°. A total of 2606 symmetry independent 2σ data were collected using graphite-monochromated Cu Ka radiation. The structure was solved by direct methods and refined by full matrix least-squares refinements (SHELX93) The final crystallographic residual is 5.7% for a model with anisotropic non-hydrogen atoms and isotropic riding hydrogens.
7. Fu, X.; Hossam, M. B.; van der Helm, D.; Schmitz, F. J. J. Am. Chem. Soc. 1995, 116, 12125-12126.