A noncleavable retro-binding peptide that spans the substrate binding cleft of serine proteases. Atomic structure of nazumamide A: Human thrombin

Journal of the American Chemical Society

Volumn 118, Issue 29, 1996, Pages 6807-6810

  Nienaber, Vicki L ^a   Amparo, Eugene C ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; NATURAL PRODUCT; SERINE PROTEINASE; THROMBIN;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; HYDROGEN BOND; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

EID: 0029895694     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja960045t     Document Type: Article

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25. We thank Frank Lewandowski for growing the thrombin crystals and Drs. Richard Alexander and Robert Galemmo for helpful discussions. V.L.N. thanks the DuPont Merck post-doctoral program for financial support.