Targeted replacement of the mycocerosic acid synthase gene in Mycobacterium bovis BCG produces a mutant that lacks mycosides

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 10, 1996, Pages 4787-4792

  Azad, Abul K ^a   Sirakova, Tatiana D ^a   Rogers, Linda M ^a   Kolattukudy, Pappachan E ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

gene replacement; homologous recombination; tuberculosis

Indexed keywords

BCG VACCINE;

ARTICLE; BACTERIAL CELL WALL; CROSSING OVER; GENE MUTATION; GENETIC RECOMBINATION; INTRON; MYCOBACTERIUM BOVIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUBERCULOSIS;

ACYLTRANSFERASES; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CINNAMATES; DNA PRIMERS; DNA, BACTERIAL; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; FATTY ACIDS; GENE TARGETING; GENES, BACTERIAL; HYGROMYCIN B; MOLECULAR SEQUENCE DATA; MUTATION; MYCOBACTERIUM BOVIS; POLYMERASE CHAIN REACTION; TRANSFORMATION, GENETIC;

EID: 0029895614     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.10.4787     Document Type: Article

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