Synthesis and X-ray crystal structure of trans,cis-[Pt(OAc)2I2(en)]: A novel type of cisplatin analog that can be photolyzed by visible light to DNA-binding and cytotoxic species in vitro

Journal of Medicinal Chemistry

Volumn 39, Issue 13, 1996, Pages 2499-2507

  Kratochwil, Nicole A ^a   Zabel, Manfred ^a   Range, Klaus Jürgen ^a   Bednarski, Patrick J ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CISPLATIN DERIVATIVE; DIACETATODIIODO(ETHYLENEDIAMINE)PLATINUM(IV); UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CANCER; CANCER CELL; COVALENT BOND; CRYSTAL STRUCTURE; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; NONHUMAN; PHOTOLYSIS; X RAY ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL DIVISION; CRYSTALLOGRAPHY, X-RAY; DNA; DNA ADDUCTS; DRUG STABILITY; HUMANS; LIGHT; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; ORGANOPLATINUM COMPOUNDS; PHOTOLYSIS; SPECTROPHOTOMETRY, ULTRAVIOLET; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0029895177     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9509105     Document Type: Article

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