Stability of nicardipine hydrochloride in intravenous solutions

American Journal of Health-System Pharmacy

Volumn 53, Issue 14, 1996, Pages 1701-1705

  Baaske, D Michael ^a,b,e   Demay, John F ^c   Latona, Candace A ^c   Mirmira, Shantha ^d   Sigvardson, Ken W ^c  

^a Research and Development   (United States)

^b Analytical Research and Development   (United States)

^c DUPONT COMPANY   (United States)

^d Fujisawa USA   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Additives; Cardiac drugs; Concentration; Containers; Dextrose; Diluents; Glass; Incompatibilities; Inje ctions; Nicardipine hydrochloride; Polyvinyl chloride; Precipitation; Ringer's injection lactated; Sodium bicarbonate; Stability; Storage

Indexed keywords

CARDIAC AGENT; DRUG ADDITIVE; GLUCOSE; NICARDIPINE; RINGER LACTATE SOLUTION;

ARTICLE; DRUG INCOMPATIBILITY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; OPTICAL DENSITY; PH; PRIORITY JOURNAL; SAMPLING;

EID: 0029895132     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/53.14.1701     Document Type: Article

References (2)

1. Halpern NA, Colucci RD, Alicea M et al. The compatibility of nicardipine hydrochloride injection with various ICU medications during simulated Y-site injection. Int J Clin Pharmacol Ther Toxicol. 1989; 27:250-4.
2. Halpern NA, Colucci RD, Alicea M et al. Visual compatibility of enalaprilat with commonly used critical care medications during simulated Y-site injection. Int J Clin Pharmacol Ther Toxicol 1989; 27:294-7.