메뉴 건너뛰기




Volumn 243, Issue 7, 1996, Pages 536-542

Patterns of disease activity in multiple sclerosis patients: A study with quantitative gadolinium-enhanced brain MRI and cytokine measurement in different clinical subgroups

Author keywords

Cytokines; Gadolinium; Magnetic resonance imaging; Multiple sclerosis

Indexed keywords

CYTOKINE; GADOLINIUM; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 0029894358     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00886876     Document Type: Article
Times cited : (37)

References (55)
  • 1
    • 0025054636 scopus 로고
    • Elevated soluble interleukin-2 receptor levels in patients with active multiple sclerosis
    • Adachi K, Kumamoto T, Araki S (1990) Elevated soluble interleukin-2 receptor levels in patients with active multiple sclerosis. Ann Neurol 28:687-691
    • (1990) Ann Neurol , vol.28 , pp. 687-691
    • Adachi, K.1    Kumamoto, T.2    Araki, S.3
  • 2
    • 0025060406 scopus 로고
    • Quantitative multiple sclerosis plaque assessment with magnetic resonance imaging. Its correlation with clinical parameters, evoked potentials and intrablood-brain-barrier IgG synthesis
    • Baumhefner RW, Tourtellotte WW, Syndulko K, Waluch V, Ellison GW, Meyers LW, Cohen SN, Osborne M, Shapshak P (1990) Quantitative multiple sclerosis plaque assessment with magnetic resonance imaging. Its correlation with clinical parameters, evoked potentials and intrablood-brain-barrier IgG synthesis. Arch Neurol 47:19-26
    • (1990) Arch Neurol , vol.47 , pp. 19-26
    • Baumhefner, R.W.1    Tourtellotte, W.W.2    Syndulko, K.3    Waluch, V.4    Ellison, G.W.5    Meyers, L.W.6    Cohen, S.N.7    Osborne, M.8    Shapshak, P.9
  • 3
    • 0025778577 scopus 로고
    • Tumour necrosis factorα synthesis by cerebrospinal-fluid-derived T cell clones from patients with multiple sclerosis
    • Benvenuto R, Paroli M, Buttinelli C, Franco A, Barnaba V, Fieschi C, Balsano F (1991) Tumour necrosis factorα synthesis by cerebrospinal-fluid-derived T cell clones from patients with multiple sclerosis. Clin Exp Immunol 84:97-102
    • (1991) Clin Exp Immunol , vol.84 , pp. 97-102
    • Benvenuto, R.1    Paroli, M.2    Buttinelli, C.3    Franco, A.4    Barnaba, V.5    Fieschi, C.6    Balsano, F.7
  • 6
    • 0026652761 scopus 로고
    • Oligometric tumour necrosis factor α slowly converts into inactive forms at bioactive levels
    • Corti A, Fassina G, Marcucei F, Barbanti E, Cassani G (1992) Oligometric tumour necrosis factor α slowly converts into inactive forms at bioactive levels. Biochem J 284:905-910
    • (1992) Biochem J , vol.284 , pp. 905-910
    • Corti, A.1    Fassina, G.2    Marcucei, F.3    Barbanti, E.4    Cassani, G.5
  • 7
    • 0028574813 scopus 로고
    • Tumor necrosis factor a quantification by ELISA and bioassay: Effects of TNF-α soluble receptor (p55) complex dissociation during assay incubations
    • Corti A, Poiesi C, Merli S, Cassani G (1994) Tumor necrosis factor a quantification by ELISA and bioassay: effects of TNF-α soluble receptor (p55) complex dissociation during assay incubations. J Immunol Methods 177: 191-198
    • (1994) J Immunol Methods , vol.177 , pp. 191-198
    • Corti, A.1    Poiesi, C.2    Merli, S.3    Cassani, G.4
  • 8
    • 0025858545 scopus 로고
    • Cerebrospinal fluid levels of myelin protein-like material and soluble interleukin-2 receptor in multiple sclerosis
    • Fesenmeier JT, Whitaker JT, Herman PK, Walker DP (1991) Cerebrospinal fluid levels of myelin protein-like material and soluble interleukin-2 receptor in multiple sclerosis. J Neuroimmunol 34:77-80
    • (1991) J Neuroimmunol , vol.34 , pp. 77-80
    • Fesenmeier, J.T.1    Whitaker, J.T.2    Herman, P.K.3    Walker, D.P.4
  • 9
    • 0028359265 scopus 로고
    • Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis
    • Filippi M, Horsfield MA, Morrissey SP, MacManus DG, Rudge P, McDonald WI, Miller DH (1994) Quantitative brain MRI lesion load predicts the course of clinically isolated syndromes suggestive of multiple sclerosis. Neurology 44:635-641
    • (1994) Neurology , vol.44 , pp. 635-641
    • Filippi, M.1    Horsfield, M.A.2    Morrissey, S.P.3    MacManus, D.G.4    Rudge, P.5    McDonald, W.I.6    Miller, D.H.7
  • 10
    • 0028793580 scopus 로고    scopus 로고
    • Comparison of triple dose vs standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with primary progressive multiple sclerosis
    • in press
    • Filippi M, Campi A, Martinelli V, Colombo B, Yousry T, Canal N, Scotti G, Comi G (in press) Comparison of triple dose vs standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with primary progressive multiple sclerosis. J Neurol Neurosurg Psychiatry
    • J Neurol Neurosurg Psychiatry
    • Filippi, M.1    Campi, A.2    Martinelli, V.3    Colombo, B.4    Yousry, T.5    Canal, N.6    Scotti, G.7    Comi, G.8
  • 12
    • 0026074551 scopus 로고
    • Interleukin-6 is elevated in plasma in multiple sclerosis
    • Frei K, Fredrikson S, Fontana A, Link H (1991) Interleukin-6 is elevated in plasma in multiple sclerosis. J Neuroimmunol 31:147-153
    • (1991) J Neuroimmunol , vol.31 , pp. 147-153
    • Frei, K.1    Fredrikson, S.2    Fontana, A.3    Link, H.4
  • 13
    • 0024427260 scopus 로고
    • Immune activation in multiple sclerosis: Study of IL-2, sIL-2R and γ-IFN levels in serum and cerebrospinal fluid
    • Gallo P, Piccinno MG, Pagni S, Argentiero V, Giometto B, Bozza F, Tavolato B (1989) Immune activation in multiple sclerosis: study of IL-2, sIL-2R and γ-IFN levels in serum and cerebrospinal fluid. J Neurol Sci 92:9-15
    • (1989) J Neurol Sci , vol.92 , pp. 9-15
    • Gallo, P.1    Piccinno, M.G.2    Pagni, S.3    Argentiero, V.4    Giometto, B.5    Bozza, F.6    Tavolato, B.7
  • 15
    • 0025107677 scopus 로고
    • Cytokine accumulations in CSF of multiple sclerosis patients: Frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6
    • Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA (1990) Cytokine accumulations in CSF of multiple sclerosis patients: frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology 40:1735-1739
    • (1990) Neurology , vol.40 , pp. 1735-1739
    • Hauser, S.L.1    Doolittle, T.H.2    Lincoln, R.3    Brown, R.H.4    Dinarello, C.A.5
  • 16
    • 0025218689 scopus 로고
    • Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental encephalomyelitis studied by gadolinium-DTPA and protein markers
    • Hawkins CP, Munro PMG, MacKenzie F, Kesselring G, Tofts PS, duBoulay EPGH, Landon DN, McDonald WI (1990) Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental encephalomyelitis studied by gadolinium-DTPA and protein markers. Brain 113: 365-378
    • (1990) Brain , vol.113 , pp. 365-378
    • Hawkins, C.P.1    Munro, P.M.G.2    MacKenzie, F.3    Kesselring, G.4    Tofts, P.S.5    DuBoulay, E.P.G.H.6    Landon, D.N.7    McDonald, W.I.8
  • 17
    • 0027506423 scopus 로고
    • Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients
    • Imamura K, Suzumura A, Hayashi F, Marunouchi T (1993) Cytokine production by peripheral blood monocytes/macrophages in multiple sclerosis patients. Acta Neurol Scand 87:281-285
    • (1993) Acta Neurol Scand , vol.87 , pp. 281-285
    • Imamura, K.1    Suzumura, A.2    Hayashi, F.3    Marunouchi, T.4
  • 18
    • 0027503708 scopus 로고
    • Correlation between magnetic resonance imaging and lesion development in chronic active multiple sclerosis
    • Katz D, Taubenberger JK, Cannella B, McFarlin DE, Raine CS, McFarland HF (1993) Correlation between magnetic resonance imaging and lesion development in chronic active multiple sclerosis. Ann Neurol 34:661-669
    • (1993) Ann Neurol , vol.34 , pp. 661-669
    • Katz, D.1    Taubenberger, J.K.2    Cannella, B.3    McFarlin, D.E.4    Raine, C.S.5    McFarland, H.F.6
  • 19
    • 0024990661 scopus 로고
    • Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: Pathogenetic and clinical implications
    • Kermode AG, Thompson AJ, MacManus DG, Kendall BE, Kingsley DPE, Moseley IF, Rudge P, McDonald WI (1990) Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis: pathogenetic and clinical implications. Brain 113:1477-1489
    • (1990) Brain , vol.113 , pp. 1477-1489
    • Kermode, A.G.1    Thompson, A.J.2    MacManus, D.G.3    Kendall, B.E.4    Kingsley, D.P.E.5    Moseley, I.F.6    Rudge, P.7    McDonald, W.I.8
  • 20
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An Expanded Disability Status Scale (EDSS)
    • Kurtzke JF (1983) Rating neurologic impairment in multiple sclerosis: an Expanded Disability Status Scale (EDSS). Neurology 33:1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 21
    • 0026066932 scopus 로고
    • Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis
    • Maimone D, Gregory S, Arnason BG, Reder AT (1991) Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis. J Neuroimmunol 32:67-74
    • (1991) J Neuroimmunol , vol.32 , pp. 67-74
    • Maimone, D.1    Gregory, S.2    Arnason, B.G.3    Reder, A.T.4
  • 23
    • 0027407956 scopus 로고
    • Cytokine-regulated adhesion between encephalitogenic T lymphocytes and cerebrovascular endothelial cells
    • McCarron RM, Wang L, Racke MK, et al (1993) Cytokine-regulated adhesion between encephalitogenic T lymphocytes and cerebrovascular endothelial cells. J Neuroimmunol 43:23-30
    • (1993) J Neuroimmunol , vol.43 , pp. 23-30
    • McCarron, R.M.1    Wang, L.2    Racke, M.K.3
  • 24
    • 0026733704 scopus 로고
    • Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome
    • Merrill JE (1992) Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome. J Immunother 12:167-170
    • (1992) J Immunother , vol.12 , pp. 167-170
    • Merrill, J.E.1
  • 27
    • 0027381828 scopus 로고
    • Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis
    • Miller DH, Barkhof F, Nauta JJP (1993) Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 116:1077-1094
    • (1993) Brain , vol.116 , pp. 1077-1094
    • Miller, D.H.1    Barkhof, F.2    Nauta, J.J.P.3
  • 28
    • 0025871038 scopus 로고
    • Multiple sclerosis: Histopathologic and MR and/or CT correlation in 37 cases at biopsy and three cases at autopsy
    • Nesbit GM, Forbes GS, Scheithauer BW, Okazaki H, Rodriguez M (1991) Multiple sclerosis: histopathologic and MR and/or CT correlation in 37 cases at biopsy and three cases at autopsy. Radiology 180:467-474
    • (1991) Radiology , vol.180 , pp. 467-474
    • Nesbit, G.M.1    Forbes, G.S.2    Scheithauer, B.W.3    Okazaki, H.4    Rodriguez, M.5
  • 29
    • 0027948840 scopus 로고
    • Role of cytokines in multiple sclerosis and experimental immune encephalomyelitis
    • Olsson T (1994) Role of cytokines in multiple sclerosis and experimental immune encephalomyelitis. Eur J Neurol 1:7-19
    • (1994) Eur J Neurol , vol.1 , pp. 7-19
    • Olsson, T.1
  • 31
    • 0023852947 scopus 로고
    • A follow-up study of very low field MRI findings and clinical course in multiple sclerosis
    • Palo J, Ketonen L, Wikstrom M (1988) A follow-up study of very low field MRI findings and clinical course in multiple sclerosis. J Neurol Sci 84: 177-187
    • (1988) J Neurol Sci , vol.84 , pp. 177-187
    • Palo, J.1    Ketonen, L.2    Wikstrom, M.3
  • 32
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma Interferon: Exacerbations associated with activation of immune system
    • Panitch HS, Hirsch RL, Schindler L, Johnson KP (1987) Treatment of multiple sclerosis with gamma Interferon: exacerbations associated with activation of immune system. Neurology 37: 1097-1103
    • (1987) Neurology , vol.37 , pp. 1097-1103
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, L.3    Johnson, K.P.4
  • 33
    • 0025976467 scopus 로고
    • Serum and CSF levels of IL-2, s-IL-2R, TNF-α, and IL-1 β in chronic-progressive multiple sclerosis: Expected lack of clinical utility
    • Peter JB, Boctor FN, Tourtellotte WW (1991) Serum and CSF levels of IL-2, s-IL-2R, TNF-α, and IL-1 β in chronic-progressive multiple sclerosis: expected lack of clinical utility. Neurology 41:121-123
    • (1991) Neurology , vol.41 , pp. 121-123
    • Peter, J.B.1    Boctor, F.N.2    Tourtellotte, W.W.3
  • 35
    • 0028227138 scopus 로고
    • McFarlin Memorial Lecture: The immunology of the multiple sclerosis lesion
    • Raine CS (1994) McFarlin Memorial Lecture: the immunology of the multiple sclerosis lesion. Ann Neurol 36 [Suppl]: S61-S72
    • (1994) Ann Neurol , vol.36 , Issue.SUPPL.
    • Raine, C.S.1
  • 36
    • 84993913357 scopus 로고
    • Multiple sclerosis: TNF revisited, with promise
    • Raine CS (1995) Multiple sclerosis: TNF revisited, with promise. Nature Med 1:211-214
    • (1995) Nature Med , vol.1 , pp. 211-214
    • Raine, C.S.1
  • 37
    • 0028132773 scopus 로고
    • A comparison of the pathology of primary and secondary progressive multiple sclerosis
    • Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI (1994) A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 117:759-765
    • (1994) Brain , vol.117 , pp. 759-765
    • Revesz, T.1    Kidd, D.2    Thompson, A.J.3    Barnard, R.O.4    McDonald, W.I.5
  • 39
    • 0028985320 scopus 로고
    • Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • Rieckmann P, Albrecht M, Kitze B, Weber T, Tumani H, Broocks A, Luer W, Helwig A, Poser S (1995) Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 37: 82-88
    • (1995) Ann Neurol , vol.37 , pp. 82-88
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3    Weber, T.4    Tumani, H.5    Broocks, A.6    Luer, W.7    Helwig, A.8    Poser, S.9
  • 40
    • 0027153235 scopus 로고
    • Oligodendrocyte injury is an early event in lesions of multiple sclerosis
    • Rodriguez M, Scheitauer BW, Forbes G, Kelly PJ (1993) Oligodendrocyte injury is an early event in lesions of multiple sclerosis. Mayo Clin Proc 68: 627-636
    • (1993) Mayo Clin Proc , vol.68 , pp. 627-636
    • Rodriguez, M.1    Scheitauer, B.W.2    Forbes, G.3    Kelly, P.J.4
  • 41
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj KW, Raine CS (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339-346
    • (1988) Ann Neurol , vol.23 , pp. 339-346
    • Selmaj, K.W.1    Raine, C.S.2
  • 42
    • 0025773147 scopus 로고
    • Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis
    • Sharief MK, Hentges R (1991) Association between tumor necrosis factor-α and disease progression in patients with multiple sclerosis. N Engl J Med 325:467-472
    • (1991) N Engl J Med , vol.325 , pp. 467-472
    • Sharief, M.K.1    Hentges, R.2
  • 43
    • 0026596353 scopus 로고
    • In vivo relationship of tumor necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis
    • Sharief MK, Thompson EJ (1992) In vivo relationship of tumor necrosis factor-α to blood-brain barrier damage in patients with active multiple sclerosis. J Neuroimmunol 38:27-33
    • (1992) J Neuroimmunol , vol.38 , pp. 27-33
    • Sharief, M.K.1    Thompson, E.J.2
  • 44
    • 0027329179 scopus 로고
    • In vivo relationship of interleukin-2 and soluble IL-2 receptor to blood-brain barrier impairment in patients with active multiple sclerosis
    • Sharief MK, Hentges R, Ciardi M, Thompson EJ (1993) In vivo relationship of interleukin-2 and soluble IL-2 receptor to blood-brain barrier impairment in patients with active multiple sclerosis. J Neurol 240:46-50
    • (1993) J Neurol , vol.240 , pp. 46-50
    • Sharief, M.K.1    Hentges, R.2    Ciardi, M.3    Thompson, E.J.4
  • 45
    • 0028842163 scopus 로고
    • Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission
    • Shaw CE, Dumbar PR, Macaulay HA, Neale TJ (1995) Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission. J Neurol 242:53-58
    • (1995) J Neurol , vol.242 , pp. 53-58
    • Shaw, C.E.1    Dumbar, P.R.2    Macaulay, H.A.3    Neale, T.J.4
  • 47
    • 0029161628 scopus 로고
    • Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized controlled trial
    • The IFNB MS Study Group and the UBC MS/MRI Analysis Group (1995) Interferon beta-1b in the treatment of multiple sclerosis: final outcome of the randomized controlled trial. Neurology 45:1277-1285
    • (1995) Neurology , vol.45 , pp. 1277-1285
  • 50
    • 0025764326 scopus 로고
    • Serum cytokine levels in chronic progressive multiple sclerosis: IL-2 levels parallel TNF-α levels
    • Trotter JL, Collins KG, Veen RC van der (1991) Serum cytokine levels in chronic progressive multiple sclerosis: IL-2 levels parallel TNF-α levels. J Neuroimmunol 33:29-36
    • (1991) J Neuroimmunol , vol.33 , pp. 29-36
    • Trotter, J.L.1    Collins, K.G.2    Van Der Veen, R.C.3
  • 51
    • 0025336505 scopus 로고
    • Improved correlation of magnetic resonance imaging with clinical status in multiple sclerosis by use of an extensive standardized imaging-protocol
    • Truyen L, Gheuens J, Van de Vyver FL, Parizel PM, Peersman GV, Martin J-J (1990) Improved correlation of magnetic resonance imaging with clinical status in multiple sclerosis by use of an extensive standardized imaging-protocol. J Neurol Sci 96:173-182
    • (1990) J Neurol Sci , vol.96 , pp. 173-182
    • Truyen, L.1    Gheuens, J.2    Van De Vyver, F.L.3    Parizel, P.M.4    Peersman, G.V.5    Martin, J.-J.6
  • 52
    • 0025856580 scopus 로고
    • Tumor necrosis factor and interleukin-1 in the CSF and sera of patients with multiple sclerosis
    • Tsukada N, Miyagi K, Matsuda M, Yanagisawa N, Yone K (1991) Tumor necrosis factor and interleukin-1 in the CSF and sera of patients with multiple sclerosis. J Neurol Sci 102:230-234
    • (1991) J Neurol Sci , vol.102 , pp. 230-234
    • Tsukada, N.1    Miyagi, K.2    Matsuda, M.3    Yanagisawa, N.4    Yone, K.5
  • 53
    • 0027845224 scopus 로고
    • Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization
    • Woodrofe MN, Cuzner ML (1993) Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 5:583-588
    • (1993) Cytokine , vol.5 , pp. 583-588
    • Woodrofe, M.N.1    Cuzner, M.L.2
  • 54
    • 0026549478 scopus 로고
    • T cell receptor Va-Vb repertoire and cytokine gene expression in active multiple sclerosis lesions
    • Wucherpfennig KW, Newcombe J, Li H, Keddy C, Cuzner ML, Hafler DA (1992) T cell receptor Va-Vb repertoire and cytokine gene expression in active multiple sclerosis lesions. J Exp Med 175:993-1002
    • (1992) J Exp Med , vol.175 , pp. 993-1002
    • Wucherpfennig, K.W.1    Newcombe, J.2    Li, H.3    Keddy, C.4    Cuzner, M.L.5    Hafler, D.A.6
  • 55
    • 0028228282 scopus 로고
    • Increased expression of high affinity IL-2 receptors and b-adrenoceptors on peripheral blood mononuclear cells is associated with clinical and MRI activity in multiple sclerosis
    • Zoukos Y, Kidd D, Woodrofe MN, Kendall BE, Thompson AJ, Cuzner ML (1994) Increased expression of high affinity IL-2 receptors and b-adrenoceptors on peripheral blood mononuclear cells is associated with clinical and MRI activity in multiple sclerosis. Brain 117:307-315
    • (1994) Brain , vol.117 , pp. 307-315
    • Zoukos, Y.1    Kidd, D.2    Woodrofe, M.N.3    Kendall, B.E.4    Thompson, A.J.5    Cuzner, M.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.