Synthesis of indole-N-propionitrile, N-propionic acid and N-propionamide derivatives of potential biological activity

Bollettino Chimico Farmaceutico

Volumn 135, Issue 1, 1996, Pages 24-30

  El Desokey, S I ^a   Hammad, M ^b   Grant, N ^b   El Telbany, E M ^b   Abdel Rahman, A H ^a  

^a Mansoura University   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

antimicrobial activity; cyanoethylation; heterocyclic; indole; oxindole

Indexed keywords

AMPICILLIN; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; CHLORAMPHENICOL; ERYTHROMYCIN; INDOLE DERIVATIVE; PROPIONIC ACID DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROPHOTOMETRY; NUCLEAR MAGNETIC RESONANCE;

AMIDES; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BACTERIA; FUNGI; MICROBIAL SENSITIVITY TESTS; NITRILES; PROPIONIC ACIDS;

EID: 0029894217     PISSN: 00066648     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Arbusou, A.E.; Saizew, J.A. and Roumov. A.J. Ber. 68 (1935) 1792-94.
2. Jacob, S.U.S. 3, 551, 451 (1970), C.A. 74 (1971) 141523n.
3. Youngaale, G.A.; Glenn, E.M.; Leduicer, D. and Szmuskovicz, J. J. Med. Chem. 12 (1969) 948.
4. Il'yuchenok, T.Yu; Lepekhin, V.P. and Shadursku, K.S. Obninsk (1965) 67-8 (Russ.), C.A.: 65 (1966) 17570.
5. Il'yuchenok, T.Yu; Lepekhin, V.P. and Shadursku, K.S. Obninsk (1965) 67-8 (Russ.), C.A.: 65 (1966) 17570.
6. Mudry, C. and Frsca, A.R. Tetrahedron 30 (1974) 2983-91.
7. Nakatsubo, F.; Fukuyama, T.; Cocuzzat.J. and Kishi, Y.J. Am. Chem. Soc. 99 (1977) 8115-6.
8. Udo, F. and Erhard, R., Arch. Pharm. (Weinheim) 309 (1976) 185-9.
9. Berti G; Dasettim, A. and Nannipien, E. J. Chem. Soc. (1968) 245.
10. Japp, F.R. and Murray, T.S., J. Chem. Soc., 85 (1894) 889.
11. Abdel-Rahman, A.H: Kandeel. E.M.; Amer F.A.: El-Sayed I. El-Desoky Egypt. J. Chem. 30 (1987) 231-8.
12. Chemistry Dissertation, Mansoura University, Mansoura, Egypt, M.Sc. Thesis of I. El-Ghamry (1990).
13. Bell, Malcolm Rie (Sterling Drug Inc.) Ger. Offen. 1, 908, 541 (Cl CO7d, A61K) C.A.: 72 (1970) 66807.
14. Kaspark and Heacock, Can. J. Chem. 44 (1966) 2805-11.