Cell membrane permeability and mitochondrial dysfunction-inducing activities in cell-free supernatants from Serpulina hyodysenteriae serotypes 1 and 2

Comparative Immunology, Microbiology and Infectious Diseases

Volumn 19, Issue 3, 1996, Pages 233-244

  Witters, Nancy A ^a   Duhamel, Gerald E ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

Hemolysin; Lymphocytes; Pathogenesis; Serpulina hyodysenteriae; Swine; Swine dysentery; Toxin

Indexed keywords

BACTERIAL TOXIN; HEMOGLOBIN; LACTATE DEHYDROGENASE; TOXIN;

ANIMAL CELL; ARTICLE; BRACHYSPIRA; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DYSENTERY; ENZYME RELEASE; ERYTHROCYTE; HEMOLYSIS; INTESTINE INFECTION; MITOCHONDRION; NONHUMAN; REDUCTION; SEROTYPE; SWINE DISEASE;

ANIMALIA; BACTERIA (MICROORGANISMS); BRACHYSPIRA; BRACHYSPIRA HYODYSENTERIAE; SUIDAE; SUS SCROFA;

EID: 0029893889     PISSN: 01479571     EISSN: None     Source Type: Journal    
DOI: 10.1016/0147-9571(96)00009-4     Document Type: Article

References (38)

1. Taylor D. J. and Alexander T. J. L. The production of dysentery in swine by feeding cultures containing a spirochaete. Br. Vet. J. 127, 58-61 (1971).
2. Harris D. L., Glock R. D., Christensen C. R. and Kinyon J. M. Swine Dysentery - I Inoculation of pigs with Treponema hyodysenteriae (new species) and reproduction of the disease. Vet. Med. Small Anim. Clin. 67, 61-64 (1972).
3. Stanton T. B., Jensen N. S., Casey T. A., Tordoff L. A., Dewhirst F. E. and Paster B. J. Reclassification of Treponema hyodysenteriae and Treponema innocens in a genus, Serpula gen. nov., as Serpula hyodysenteriae comb. nov. and Serpula innocens comb. nov. Int. J. Syst Bacteriol. 41, 50-58 (1991).
4. Stanton T. B. Proposal to change the genus designation Serpula to Serpulina gen. nov. containing the species Serpulina hyodysenteriae comb. nov. and Serpulina innocens comb. nov. Int. J. Syst. Bacteriol. 42, 189-190 (1992).
5. Mapother M. E. and Joens L. A. New serotypes of Treponema hyodysenteriae. J. Clin. Microbiol. 22, 161-164 (1985).
6. Li Z., Bélanger M. and Jacques M. Serotyping of Canadian isolates of Treponema hyodysenteriae and description of two new serotypes. J. Clin. Microbiol. 29, 2794-2797 (1991).
7. Hampson D. J. New serogroups of Treponema hyodysenteriae (G, H, and I). Vet. Rec. 127, 524 (1990).
8. Kinyon J. M., Songer J. G., Janc M. and Harris D. L. Isolation and identification of Treponema hyodysenteriae: aid to the diagnosis and treatment of swine dysentery. Proc. Am. Assoc. Vet. Lab. Diagn. 19, 65-74 (1976).
9. Mysore J. V. and Duhamel G. E. Morphometric analysis of enteric lesions in C3H/HeN mice inoculated with Serpulina hyodysenteriae serotypes 2 and 4 with or without oral streptomycin pretreatment. Can. J. Vet. Res. 58, 281-286 (1994).
10. Joens L. A., Songer J. G., Harris D. L. and Glock R. D. Experimental infection with Treponema hyodysenteriae in guinea pigs. Infect. Immun. 22, 132-135 (1978).
11. Sueyoshi M. and Adachi Y. Diarrhea induced by Treponema hyodysenteriae: a young chick cecal model for swine dysentery. Infect. Immun. 58, 3348-3362 (1990).
12. Jensen N. S. and Stanton T. B. Comparison of Serpulina hyodysenteriae B78, the type strain of the species, with other S. hyodysenteriae strains using enteropathogenicity studies and restriction fragment length polymorphism analysis. Vet. Microbiol. 36, 221-231 (1993).
13. Hudson M. J., Alexander T. J. L., Lysons R. J. and Wellstead P. D. Swine dysentery: failure of an attenuated strain of spirochete given orally to protect pigs against subsequent challenge. Brit. Vet. J. 130, 37-40 (1974).
14. Lee J. I., Hampson D. J., Combs B. G. and Lymbery A. J. Genetic relationships between isolates of Serpulina (Treponema) hyodysenteriae, and comparison of methods for their subspecific differentiation. Vet. Microbiol. 34, 35-46 (1993).
15. Milner J. A. and Sellwood R. Chemotactic response to mucin by Serpulina hyodysenteriae and other porcine spirochetes: potential role in intestinal colonization. Infect. Imunn. 62, 4095-4099 (1994).
16. Saheb S. A., Massicotte L. and Picard B. Purification and characterization of Treponema hyodysenteriae hemolysin. Biochimie 62, 779-785 (1980).
17. Picard B., Massicotte L. and Saheb S. A. Effect of sodium ribonucleate on the growth and hemolytic activity of Treponema hyodysenteriae. Experientia 35, 484-486 (1979).
18. Lemcke R. M. and Burrows M. R. Studies on a hemolysin produced by Treponema hyodysenteriae. J. Med. Microbiol. 15, 205-214 (1982).
19. Bernheimer A. W. Formation of a bacterial toxin (streptolysin S) by resting cells. J. Exp. Med. 90, 373-392 (1949).
20. Kent K. A. and Lemcke R. M. Purification and cytotoxic activity of a haemolysin produced by Treponema hyodysenteriae. In 8th IPVS Proc. p. 185. IPVS, Belgium (1984).
21. Kent K. A., Lemcke R. M. and Lysons R. J. Production, purification, and molecular weight determination of the hemolysin of Treponema hyodysenteriae. J. Med. Microbiol. 27, 215-224 (1988).
22. Ginsburg I. Mechanisms of cell and tissue injury induced by group A streptococci: relation to post-streptococcal sequelae. J. Infect. Dis. 126, 294-340 (1972).
23. Keiser H., Weissman G. and Bernheimer A. W. Studies on liposomes. IV. Solubilization of enzymes during mitochondrial swelling and disruption of lysosomes by streptolysin S and other hemolytic agents. J. Cell Biol. 22, 101-113 (1964).
24. Lysons R. J., Kent K. A., Bland A. P., Sellwood R., Robinson W. F. and Frost A. J. A cytotoxic hemolysin from Treponema hyodysenteriae - a probable virulence determinant in swine dysentery. J. Med. Microbiol. 34, 97-102 (1991).
25. Bland A. P., Frost A. J. and Lysons R. J. Susceptibility of porcine ileal enterocytes to the cytotoxin of Serpulina hyodysenteriae and the resolution of the epithelial lesions: an electron microscopic study. Vet. Pathol. 32, 24-35 (1995).
26. ter Huurne A. A. H. M., van Houten M., Muir S., Kusters J. G., van der Zeijst B. A. M. and Gaastra W. Inactivation of a Serpulina (Treponema) hyodysenteriae hemolysin gene by homologous recombination: importance of this hemolysin in pathogenesis of S. hyodysenteriae in mice. FEMS Microbiol. Lett. 92, 109-114 (1992).
27. Hyatt D. R., ter Huurne A. A. H. M., van der Zeijst B. A. M. and Joens L. A. Reduced virulence of Serpulina hyodysenteriae hemolysin-negative mutants in pigs and their potential to protect pigs against challenge with a virulent strain. Infect. Immun. 62, 2244-2248 (1994).
28. Hampson D. J. Slide-agglutination for rapid serological typing of Treponema hyodysenteriae. Epidemiol. Infect. 106, 541-547 (1991).
29. Elder R. O., Duhamel G. E., Schafer R. W., Mathiesen M. R. and Ramanathan M. Rapid detection of Serpulina hyodysenteriae in diagnostic specimens by PCR. J. Clin. Microbiol. 32, 1497-1502 (1994).
30. Duhamel G. E., Bernard R. J., Mathiesen M. R. and Eskridge K. M. Comparison of six commercially available transport media for maintenance of Serpulina (Treponema) hyodysenteriae. J. Vet. Diagn. Invest. 4, 285-292 (1992).
31. Dupont D. P., Duhamel G. E., Carlson M. P. and Mathiesen M. R. Effect of divalent cations on the hemolytic activity of Serpulina (Treponema) hyodysenteriae: inhibition induced by zinc and copper. Vet. Microbiol. 41, 63-73 (1994).
32. Fedorka-Cray P. J., Stine D. L., Anderson G. A. and Huether M. J. Efficacy of cell-free extract from Actinobacillus (Haemophilus) pleuropneumoniae serotype 1 against disease in swine. Infect. Immun. 58, 358-365 (1990).
33. Vega M. V., Maheswaran S. K., Leininger J. R. and Ames T. R. Adaptation of a colorimetric microtitration assay for quantifying Pasteurella haemolytica A1 leukotoxin and antileukotoxin. Am. J. Vet. Res. 48, 1559-1564 (1987).
34. Duhamel G. E., Bernoco D., Davis W. C. and Osburn B. I. Distribution of T and B lymphocytes in mammary dry secretions, colostrum and blood of adult dairy cattle. Vet. Immunol. Immunopathol. 14, 101-122 (1987).
35. Korzeniewski C. and Callewaert D. M. An enzyme-release assay for natural cytotoxicity. J. Immun. Meth. 64, 313-320 (1983).
36. Baum D. H. and Joens L. A. Serotypes of Beta-hemolytic Treponema hyodysenteriae. Infect. Immun. 25, 792-796 (1979).
37. Clerc P., Baudry B. and Sansonetti P. J. Plasmid-mediated contact haemolytic activity in Shigella species: correlation with penetration into HeLa cells. Ann. Inst. Pasteur/Microbiol. 137A, 267-278 (1986).
38. Taylor D. J. Swine Dysentery. In Pig Diseases (Edited by Taylor D. J.), pp. 140-148. St Edmundsbury Press, Bury St Edmund's (1995).