Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5,5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells

Archives of Biochemistry and Biophysics

Volumn 330, Issue 1, 1996, Pages 3-11

  Stoyanovsky, Detcho A ^a,c   Goldman, Radoslav ^a   Jonnalagadda, Sastry S ^a   Day, Billy W ^a,b   Claycamp, H Gregg ^a,b   Kagan, Valerian E ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

DMPO; EPR; Glutathione; Glutathionyl radical; HL 60 cells; LC MS; Nitrone; NMR; Phenoxyl radical; Redox cycling; Spin trapping

Indexed keywords

2 (S GLUTATHIONYL) 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; ANTIOXIDANT; FREE RADICAL; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MEMBRANE LIPID; PYRROLINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HL 60; CHROMATOPHORE; ELECTROCHEMICAL DETECTION; ELECTRON SPIN RESONANCE; ENZYME ANALYSIS; ENZYME MECHANISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MACROMOLECULE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIC N-OXIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GLUTATHIONE; HL-60 CELLS; HUMANS; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OXIDATION-REDUCTION; PEROXIDASE; PHENOLS; REACTIVE OXYGEN SPECIES; SPECTROPHOTOMETRY, ULTRAVIOLET; SPIN LABELS;

EID: 0029893338     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1996.0219     Document Type: Article

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