Plasma kallikrein and tissue-type plasminogen activator compete for a common pathway into the liver

Immunopharmacology

Volumn 32, Issue 1-3, 1996, Pages 88-90

  Nagaoka, Marcia R ^a   Kouyoumdjian, Maria ^a   Borges, Durval R ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

Liver; Liver receptor; Plasma kallikrein; Tissue type plasminogen activator

Indexed keywords

KALLIKREIN; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; CONFERENCE PAPER; FIBRINOLYSIS; INTERNALIZATION; LIVER; LIVER PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029893149     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/0162-3109(96)88182-3     Document Type: Conference Paper

References (12)

1. Borges, D.R., Gordon, A.H., Guimaraes, J.A. and Prado, J.L. Rat plasma kallikrein clearance by perfused rat liver. Brazilian Journal of Medical and Biological Research 1985; 18: 187-194.
2. Borges, D.R., Sampaio, C.A.M., Llosa, P. and Prado, J.L. The liver is the main organ to clear plasma and tissue kallikrein from rat plasma in vivo. Advances in Experimental Medicine and Biology 1986; 198A: 229-233.
3. Borges, D.R. and Kouyoumdjian, M. The recognition factor for clearance of plasma kallikrein is located on its heavy chain and not exposed on prokallikrein. Journal of Hepatology 1992a; 16: 115-121.
4. Borges, D.R. and Kouyoumdjian, M. Chloramine T impairs the receptor-mediated endocytosis of plasma kallikrein by the liver. Agents and Actions 1992b; 38II (Suppl): 278-284.
5. Chao, J.; Tillmann, D.M.; Wang, M.; Margolius, H.S. and Chao, L. Identification of a new tissue-kallikrein-binding protein. Biochemical Journal 1986; 239: 325-331.
6. Kouyoumdjian, M.; Borges, D.R.; Michelacci, Y.M.; Guimaraes, J.A.; Sampaio, C.A.M. and Prado J.L. Purification and characterization of the alpha form of rat plasma kallikrein. Brazilian Journal of Medical and Biological Research 1987; 20: 549-552.
7. Kouyoumdjian, M., Borges, D.R., Prado, E.S. and Prado, J.L. Identification of receptors in the liver that mediate endocytosis of recirculanting tissue kallikreins. Biochimica et Biophys Acta 1989; 980: 299-304.
8. Otter, M., Kuiper, J., Bos, R., Rijken, D.C. and van Berkel, T.J.C. Characterization of the interaction both in vitro and in vivo of tissue-type plasminogen activator (tPA) with rat liver cells. Biochemical Journal 1992; 284: 545-550.
9. Seydel, W., Stang, E., Roos, N. and Krause, J. Endocytosis of the recombinant tissue plasminogen activator alteplase by hepatic endothelial cells. Arzneimittelforschung Drug Research 1991; 41: 182-186.
10. Smedsrod, B. and Einarsson, M. Clearance of tissue plasminogen activator by mannose and galactose receptors in the liver. Thrombosis and Haemostasis 1990; 63: 60-66.
11. Stang, E., Krause, J., Seydel, W., Berg, T. and Roos, N. Endocytosis and intracellular processing of tissue-type plasminogen activator by rat liver cells in vivo. Biochemical Journal 1992; 282: 841-851.
12. Toledo, C.F. and Borges, D.R. Plasma-kallikrein clearance by the liver of acetaminophen-intoxicated rats. Life Sciences, 1993; 52: 1451-1459.