Molecular analysis of the lissencephaly gene 1 (LIS-1) in medulloblastomas

Neuropathology and Applied Neurobiology

Volumn 22, Issue 3, 1996, Pages 233-242

  Koch, A ^a   Tonn, J ^b   Kraus, J A ^a   Sorensen N ^b   Albrecht, S ^c   Wiestler, O D ^a   Pietsch, T ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

LIS 1; Lissencephaly; LOH; Medulloblastoma; PNET; Tumour suppressor

Indexed keywords

THROMBOCYTE ACTIVATING FACTOR;

ADOLESCENT; ADULT; AGYRIA; ARTICLE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CELL MIGRATION; CHILD; CHROMOSOME 17P; CLINICAL ARTICLE; DNA SEQUENCE; FEMALE; GENE DELETION; GENE MUTATION; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; MALE; MEDULLOBLASTOMA; MOLECULAR GENETICS; NORTHERN BLOTTING; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE;

EID: 0029893043     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2990.1996.tb00899.x     Document Type: Article

References (33)

1. Adesina AM, Nalbantoglu J, Cavenee WK. p53 gene mutations and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res 1994; 54: 5649-51
2. Albrecht S, von Deimling A, Pietsch T, Giangaspero F, Brandner S, Kleihues P, Wiestler OD. Microsatellite analysis of loss of heterozygosity on chromosomes 9q. 11p and 17p in medulloblastomas. Neuropathol App Neurobiol 1994; 20: 74-81
3. Badiali M, Iolascon A, Loda M. p53 gene mutation in medulloblastoma. Immunohistochemistry gel shift analysis and sequencing. Diagn Mol Pathol 1993; 2: 23-8
4. Bazan NC. A signal terminator. Nature 1995; 374: 501-2
5. Biegel JA, Burk CD, Barr FG, Emanuel BS. Evidence for a 17p tumour: related locus distinct from p53 in pediatric primitive neuroectodermal tumour. Cancer Res 1992; 52: 3391-5
6. Bigner SH, Mark J, Bigner DD. Cytogenetics of human brain tumour. Cancer Genet Cytogenet 1990; 47: 141-54
7. 2+ in hippocampal neurons. Neuron 1992; 9: 285-94
8. Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC. Analysis of VNTR locus D1S80 by PCR followed by high-resolution PAGE. Am J Hum Genet 1991; 48: 137-44
9. Cogen PH, Daneshvar L, Metzger AK, Edwards MSB. Deletion mapping of the medulloblastoma locus on chromosome 17p. Genomics 1990;8: 279-85
10. Cogen PH, Daneshvar L, Metzger AK, Duyk G, Edwards MSB, Sheffield, VC. Involvement of multiple chromosome 17p loci in medulloblasloma tumor genesis. Am J Hum Genet 1992; 50: 584-9
11. Cooperative Human Linkage Centre (CHLC). A comprehensive human linkage map with centimorgan density. Science 1994; 265: 2049-54
12. Friedman HS, Burger PC, Bigner SH, Trojanowski JQ, Brodeur GM, He X, Wikstrand CJ, Kurtzberg J, Berens ME, Halperin EC, Bigner DD. Phenotypic and genotypic analysis of a human medulloblastoma cell line and transplantable xenograft (D341 Med) demonstrating amplification of c-myc. Am J Pathol 1988; 130: 472-84
13. Friedman HS, Burger PC, Bigner SH, Trojanowski JQ, Wikstrand CJ, Halperin EC, Bigner DD. Establishment and characterization of the human medulloblastoma cell line and transplantable xenograft D283 MED. J Neuropath Exp Neurol 1985; 44: 592-605
14. Hattore M, Adachi U, Tsujimoto M, Arai H, Inoue K. Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase. Nature 1994; 370: 216-8
15. Heisterkamp N, Morris C, Groffen J. ABR, an active BCR-related gene. Nucl Acids Res 1989; 17: 8821-31
16. Jacobsen PF, Jenkyn DJ, Papadimitriou JM. Establishment of a human medulloblastoma cell line and its heterotransplanlation into nude mice. J Neuropathol Exp Nurol 1985; 44: 472-85
17. Kleihues P, Burger PC, Scheithauer BW. Histological Typing of Tumours of the Central Nervous System. New York, Berlin: Springer Verlag, 1993
18. Ledbetter SA, Kuwano A, Dobyns WB, Ledbetter DH. Microdeletions of chromosome 17p13 as a cause of isolated lissencephaly. Am J Hum Genet 1992; 50: 182-9
19. Makos M, Nelkin BD, Chazin VR, Cavenee WK, Brodeur GM, Baylin SB. DNA hypermethylation is associated with 17p allelic loss in neuronal tumours. Cancer Res 1993; 53: 2715-18
20. Maniatis T, Fritsch EF, Sambrook J. Molecular cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbour Laboratory Press, 1989
21. Marshall CJ. Tumour suppressor genes. Cell 1991; 64: 313-26
22. McDonald J, Daneshvar L, Willert JR, Matsumura K, Waldman F, Cogen PH. Physical mapping of chromosome 17p13.3 in the region of a putative tumor: suppressor gene important in medulloblastoma. Genomics 1994; 23: 229-32
23. Neer EJ, Schmidt CJ, Smith T. LIS is more. Nature Genet 1993; 5: 3-4
24. Ohgaki H, Eibl RH, Wiestler OD, Yasargil MG, Newcomb EW, Kleihues P. p53 mutations in nonastrocytic human brain tumors. Cancer Res 1991; 51: 6202-5
25. Pietsch T, Scharmann T, Fonatsch C, Schmidt D, Öckler R, FReihoff D, Albrecht S, Wiestler OD, Zeltzer P, Riehm H. Characterization of live new cell lines derived from human primitive neuroectodermal tumors of the central nervous system. Cancer Res 1944; 54: 5278-87
26. Raffel C, Gilles FE, Weinberg KI. Reduction of homozygosity and gene amplification in central nervous system primitive neuroectodermal tumors of childhood. Cancer Res 1989; 50: 6572-5
27. Reiner O, Carazzo R, Shen Y, Wehnert M, Faustinella F, Dobyns WB, Caskey CT, Ledbetter DH. Isolation of Miller-Dieker lissencephaly gene containing G protein β-subunit-like repeats. Nature 1993; 364: 717-21
28. Saylors RL, Sidransky D, Friedman HS, Bigner SH, Bigner DD, Vogelstein B, Brodeur G. Infrequent p53 mutations in medulloblastoma. Cancer Res 1991; 51: 4721-3
29. Squinto SP, Block AL, Braquet P, Bazan NZ. Platelet-activating factor stimulates Fos/Jun/AP-1 transcription signaling system in human neuroblastoma cells. J Neurosci Res 1989; 24: 558-26
30. Stack M, Jones D, White G, Liscia DS, Venesio T, Casey G, Crichton D, Varley J, Mitchell E, Heighway J, Santibanez-Koref M. Detailed mapping and loss of heterozygosity analysis suggests a suppressor locus involved in sporadic breast cancer within a distal region of chromosome band 17p13.3. Human Mol Genet 1995; 4: 2047-55
31. Tenen M, Colombo BM, Polo B, Cajola L, Broggi G, Finocchiaro G. p53 mutations and microsatellite analysis of loss of heterozyosity in malignant gliomas. Cancer Genet Cytogenet 1994; 74: 139-43
32. von Deimling A, Eibl RH, Ohgaki H, Louis DN, von Ammon K, Petersen I, Kleihues P, Chung RY, Wiestler OD, Seizinger BR. p55 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma. Cancer Res 1992; 52: 2987-90
33. Wales MM, Biel MA, El Deiry W, Nelkin BD, Issa J-P, Cavenee WK, Kuerbitz SJ, Baylin S. p53 activates expression of HIC-1, a new candidate tumor suppressor gene on 17p13.3. Nature Med 1995; 1: 570-6