Ethylene oxide exposure may increase the risk of spontaneous abortion, preterm birth, and postterm birth

Epidemiology

Volumn 7, Issue 4, 1996, Pages 363-368

  Rowland, Andrew S ^a   Baird, Donna Day ^a   Shore, David L ^b   Darden, Becky ^b   Wikox, Alkn J ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b WESTAT   (United States)

Author keywords

cohort studies; dental staff; ethylene oxide; occupational air pollutants; occupational diseases; postmature infant; postterm; premature infant; prematurity; spontaneous abortion

Indexed keywords

ETHYLENE OXIDE;

ADULT; ARTICLE; FETUS WASTAGE; HUMAN; MAJOR CLINICAL STUDY; OCCUPATIONAL EXPOSURE; POSTMATURITY; PREMATURE LABOR; PREMATURITY; PRIORITY JOURNAL; PROLONGED PREGNANCY; RISK ASSESSMENT; SPONTANEOUS ABORTION;

EID: 0029892948     PISSN: 10443983     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001648-199607000-00005     Document Type: Article

References (25)

1. Landrigan PJ, Meinhardt TJ, Gordon J, Lipscomb JR, Burg JR, Mazzuckelli LF, Lewis TR, Lernen RA. Ethylene oxide: an overview of toxicologie and epidemiologic research. Am J Ind Med 1984;6:103-115.
2. World Health Organization. Environmental Health Criteria. 55: Ethylene Oxide. Geneva: World Health Organization, 1985.
3. Glaser ZR. Ethylene oxide: toxicology review and field study results of hospital use. J Environ Pathol Toxicol 1979;2:173-208.
4. Glaser ZR. Special Occupational Hazard Review with Control Recommen- dations for the Use of Ethylene Oxide as a Sterilant in Medical Facilities. DHEW Pub. No. (NIOSH)77-200. Rockville, MD: National Institute for Occupational Safety and Health, 1977.
5. Snellings WM, Zelenak JP, Weil CS. Effects on reproduction in Fischer 344 rats exposed to ethylene oxide by inhalation for one generation. Toxicol Appl Pharmacol 1982;63:382-388.
6. Generoso WM, Rutledge JC, Cain KT, Hughes LA, Braden PW. Exposure of female mice to ethylene oxide within hours after mating leads to fetal malformation and death. Mutat Res 1987;176:269-274.
7. Rutledge JC, Generoso WM. Fetal pathology produced by ethylene oxide treatment of the murine zygote. Teratology 1989;39:563-572.
8. Katoh M, Cacheiro NLA, Cornett CV, Cain KT, Rutledge JC, Generoso WM. Fetal anomalies produced subsequent to treatment of zygotes with ethylene oxide or ethyl methanesulfonate are not likely due to the usual genetic causes. Mutat Res 1989;210:337-344.
9. Generoso WM, Cain KT, Hughes LA, Sega GA, Braden PW, Gosslee DG, Shelby MD. Ethylene oxide dose and dose-rate effects in the mouse dominant-lethal test. Environ Mutagen 1986;8:l-7.
10. Snellings WM, Maronpot RR, Zelenak JP, Laffoon CP. Teratology study in Fischer 344 rats exposed to ethylene oxide by inhalation. Toxicol Appl Pharmacol 1982;64:476-481.
11. Hardin BD, Niemeier RW, Sikov MR, Hackett PL. Reproductive-toxicologie assessment of the epoxides ethylene oxide, propylene oxide, butylene oxide, and styrene oxide. Scand J Work Environ Health 1983;9:94-102.
12. Mortimer VD, Kercher SL. Control Technology for Ethylene Oxide Sterilization in Hospitals. DHHS Pub. No. (NIOSH)89-120. Cincinnati: National Institute for Occupational Safety and Health, 1989.
13. Hemminki K, Mutanen P, Saloniemi I, Niemi ML, Vainio H. Spontaneous abortions in hospital staff engaged in sterilising instruments with chemical agents. BMJ 1982;285:1461-1463.
14. Hemminki K, Kyyronen P, Lindbohm M. Spontaneous abortions and malformations in the offspring of nurses exposed to anaesthetic gases, cytostatic drugs, and other potential hazards in hospitals, based on registered information of outcome. J Epidemiol Community Health 1985;39:141-147.
15. Ribeiro LR, Salvadori DMF, Rios ACC, Costa SL, Tales AD, Törnqvist M, Natarajan AT. Biological monitoring of workers occupationally exposed to ethylene oxide. Mutat Res 1994;313:81-87.
16. Mayer J, Warburton D, Jeffrey AM, Pero R, Walles S, Andrews L, Toor M, Latriano L, Wazneh L, Tang D, Tsai WY, Kuroda M, Perera F. Biologic markers in ethylene oxide-exposed workers and controls. Mutat Res 1991; 248:163-176.
17. Florack EIM, Zielhuis GA. Occupational ethylene oxide exposure and reproduction. Int Arch Occup-Environ Health 1990;62:273-277.
18. Council on Dental Materials, Instruments, and Equipment, Council on Dental Practice, Council on Dental Therapeutics. Infection control recommendations for the dental office and the dental laboratory. J Am Dent Assoc 1988;116:241-248.
19. Rowland AS, Baird DD, Shore DL, Weinberg CR, Savitz DA, Wilcox AJ. Nitrous oxide and spontaneous abortion in female dental assistants. Am J Epidemiol 1995;141:531-538.
20. SAS Institute. The Logistic Procedure. In: SAS/Stat User's Guide. Gary, NC: SAS Institute, 1990;1120-1126.
21. Eden RD, Seifert LS, Winegar A, Spellacy WN. Maternal risk status and postdate pregnancy outcome. J Reprod Med 1988;33:53-57.
22. Kassis A, Mazor M, Leiberman JR, Cohen A, Insler V. Management of post-date pregnancy: a case control study. Isr J Med Sci 1991;27:82-86.
23. Saunders N, Paterson C. Effect of gestational age on obstetric performance: when is "term" over? Lancet 1991;338:1190-1192.
24. Bakketeig LS, Hoffman HJ, Oakley ART. Perinatal mortality. In: Bracken MB, ed. Perinatal Epidemiology. New York: Oxford University Press, 1984; 99-151.
25. Selevan SG, Lemasters GK. The dose-response fallacy in human reproductive studies of toxic exposures. J Occup Med 1987;29:451-454.