-
1
-
-
0002246510
-
The biochemical basis of anthracycline toxicity and anti-tumor activity
-
Gianni, L.; Corden, B. J.; Myers, C. E. The biochemical basis of anthracycline toxicity and anti-tumor activity. Rev. Biochem. Toxicol. 5:1-82; 1983.
-
(1983)
Rev. Biochem. Toxicol.
, vol.5
, pp. 1-82
-
-
Gianni, L.1
Corden, B.J.2
Myers, C.E.3
-
2
-
-
0026714331
-
The anthracyclines: Will we ever find a better doxorubicin?
-
Weiss, R. B. The anthracyclines: Will we ever find a better doxorubicin? Semin. Oncol. 19:670-686; 1992.
-
(1992)
Semin. Oncol.
, vol.19
, pp. 670-686
-
-
Weiss, R.B.1
-
3
-
-
0021221088
-
Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron(III) complex
-
Gutteridge, J. M. C. Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron(III) complex. Biochem. Pharmacol. 33:1725-1728; 1984.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 1725-1728
-
-
Gutteridge, J.M.C.1
-
4
-
-
0022263591
-
Characterization of the cycle of iron-mediated electron transfer from adriamycin to molecular oxygen
-
Gianni, L.; Zweier, J. L.; Levy, A.; Myers, C. E. Characterization of the cycle of iron-mediated electron transfer from adriamycin to molecular oxygen. J. Biol. Chem. 260:6820-6826; 1985.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 6820-6826
-
-
Gianni, L.1
Zweier, J.L.2
Levy, A.3
Myers, C.E.4
-
6
-
-
0018741206
-
NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals
-
Bachur, N. R.; Gordon, S. L.; Gee, M. V.; Kon, H. NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals. Proc. Natl. Acad. Sci. USA 76:954-957; 1979.
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 954-957
-
-
Bachur, N.R.1
Gordon, S.L.2
Gee, M.V.3
Kon, H.4
-
7
-
-
0017746691
-
Electron spin resonance study on the mode of generation of free radicals of daunomycin, adriamycin, and carboquone in NAD(P)H-microsome system
-
Sato, S.; Iwaizumi, M.; Hanada, K.; Tamura, Y. Electron spin resonance study on the mode of generation of free radicals of daunomycin, adriamycin, and carboquone in NAD(P)H-microsome system. Gann 68:603-608; 1977.
-
(1977)
Gann
, vol.68
, pp. 603-608
-
-
Sato, S.1
Iwaizumi, M.2
Hanada, K.3
Tamura, Y.4
-
8
-
-
0019307472
-
Spin-trapping and direct electron spin resonance investigations of the redox metabolism of quinone anticancer drugs
-
Kalyanaraman, B.; Perez-Reyes, E.; Mason, R. P. Spin-trapping and direct electron spin resonance investigations of the redox metabolism of quinone anticancer drugs. Biochim. Biophys. Acta 630:119-130; 1980.
-
(1980)
Biochim. Biophys. Acta
, vol.630
, pp. 119-130
-
-
Kalyanaraman, B.1
Perez-Reyes, E.2
Mason, R.P.3
-
9
-
-
0024205242
-
A comparison of the free radical properties of several anthracycline anti-tumour drugs and some of their analogues
-
Hoey, B. M.; Butler, J.; Lea, J. S.; Sarna, T. A comparison of the free radical properties of several anthracycline anti-tumour drugs and some of their analogues. Free Radic. Res. Commun. 5:169-176; 1988.
-
(1988)
Free Radic. Res. Commun.
, vol.5
, pp. 169-176
-
-
Hoey, B.M.1
Butler, J.2
Lea, J.S.3
Sarna, T.4
-
10
-
-
0022849760
-
2 reduction by the iron complexes of adriamycin and daunomycin: The importance of the sidechain hydroxyl group
-
2 reduction by the iron complexes of adriamycin and daunomycin: The importance of the sidechain hydroxyl group. Biochim. Biophys. Acta 884:326-336; 1986.
-
(1986)
Biochim. Biophys. Acta
, vol.884
, pp. 326-336
-
-
Zweier, J.L.1
Gianni, L.2
Muindi, J.3
Meyers, C.E.4
-
11
-
-
0025572476
-
3+-doxorubicin complex undergoing self-reduction by its α-ketol group
-
3+-doxorubicin complex undergoing self-reduction by its α-ketol group. Biochem. Cell Biol. 68:1331-1336; 1990.
-
(1990)
Biochem. Cell Biol.
, vol.68
, pp. 1331-1336
-
-
Hasinoff, B.B.1
-
12
-
-
0026585672
-
ICRF-187 permits longer treatment with doxorubicin in women with breast cancer
-
Speyer, J. L.; Green, M. D.; Zeleniuch-Jacquotte, A.; Wernz, J. C.; Rey, M.; Sanger, J.; Kramer, E.; Ferrans, V.; Hochster, H.; Meyers, M.; Blum, R. H.; Feit, F.; Attubato, M.; Burrows, W.; Muggia, F. M. ICRF-187 permits longer treatment with doxorubicin in women with breast cancer. J. Clin. Oncol. 10:117-127; 1992.
-
(1992)
J. Clin. Oncol.
, vol.10
, pp. 117-127
-
-
Speyer, J.L.1
Green, M.D.2
Zeleniuch-Jacquotte, A.3
Wernz, J.C.4
Rey, M.5
Sanger, J.6
Kramer, E.7
Ferrans, V.8
Hochster, H.9
Meyers, M.10
Blum, R.H.11
Feit, F.12
Attubato, M.13
Burrows, W.14
Muggia, F.M.15
-
13
-
-
0024573486
-
The interaction of the cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl)propane), its hydrolysis product ICRF-198, and other chelating agents with the Fe(III) and Cu(II ) complexes of adriamycin
-
Hasinoff, B. B. The interaction of the cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl)propane), its hydrolysis product ICRF-198, and other chelating agents with the Fe(III) and Cu(II ) complexes of adriamycin. Agents Actions 26:378-385; 1989.
-
(1989)
Agents Actions
, vol.26
, pp. 378-385
-
-
Hasinoff, B.B.1
-
14
-
-
0025237857
-
The iron(III) and copper(II) complexes of adriamycin promote the hydrolysis of the cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl )propane)
-
Hasinoff, B. B. The iron(III) and copper(II) complexes of adriamycin promote the hydrolysis of the cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl )propane). Agents Actions 29:374-381; 1990.
-
(1990)
Agents Actions
, vol.29
, pp. 374-381
-
-
Hasinoff, B.B.1
-
15
-
-
0020398870
-
Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis products of the antitumor agent ICRF-159 and its inactive homologue ICRF-192
-
Huang, Z.-X.; May, P. M.; Quinlan, K. M.; Williams, D. R.; Creighton, A. M. Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis products of the antitumor agent ICRF-159 and its inactive homologue ICRF-192. Agents Actions 12:536-542; 1982.
-
(1982)
Agents Actions
, vol.12
, pp. 536-542
-
-
Huang, Z.-X.1
May, P.M.2
Quinlan, K.M.3
Williams, D.R.4
Creighton, A.M.5
-
16
-
-
0027740137
-
The one-ring open hydrolysis product intermediates of the cardioprotective agent ICRF-187 (dexrazoxane) displace iron from iron-anthracycline complexes
-
Buss, J. L.; Hasinoff, B. B. The one-ring open hydrolysis product intermediates of the cardioprotective agent ICRF-187 (dexrazoxane) displace iron from iron-anthracycline complexes. Agents Actions 40:86-95; 1993.
-
(1993)
Agents Actions
, vol.40
, pp. 86-95
-
-
Buss, J.L.1
Hasinoff, B.B.2
-
17
-
-
0016775708
-
Studies on the stability and cellular distribution of dioxopiperazines in cultured BHK-21S cells
-
Dawson, K. M. Studies on the stability and cellular distribution of dioxopiperazines in cultured BHK-21S cells. Biochem. Pharmacol. 24:2249-2253; 1975.
-
(1975)
Biochem. Pharmacol.
, vol.24
, pp. 2249-2253
-
-
Dawson, K.M.1
-
18
-
-
0028989055
-
NADPH-cytochrome-P450 reductase promotes hydroxyl radical production by the iron complex of ADR-925, the hydrolysis product of ICRF-187 (dexrazoxane)
-
Hasinoff, B. B. NADPH-cytochrome-P450 reductase promotes hydroxyl radical production by the iron complex of ADR-925, the hydrolysis product of ICRF-187 (dexrazoxane). Free Radic. Res. 22:319-325; 1995.
-
(1995)
Free Radic. Res.
, vol.22
, pp. 319-325
-
-
Hasinoff, B.B.1
-
19
-
-
0028945064
-
Doxorubicin reduces the iron (III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals
-
Malisza, K. L.; Hasinoff, B. B. Doxorubicin reduces the iron (III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals. Arch. Biochem. Biophys. 316:680-688; 1995.
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 680-688
-
-
Malisza, K.L.1
Hasinoff, B.B.2
-
20
-
-
0018716636
-
Risk factors for doxorubicin-induced congestive heart failure
-
Von Hoff, D. D.; Lazard, M. W.; Basa, P.; Davis, H. L.; Von Hoff, A. L.; Rozencweig, M.; Muggia, F. Risk factors for doxorubicin-induced congestive heart failure. Ann. Intern. Med. 91:710-717; 1979.
-
(1979)
Ann. Intern. Med.
, vol.91
, pp. 710-717
-
-
Von Hoff, D.D.1
Lazard, M.W.2
Basa, P.3
Davis, H.L.4
Von Hoff, A.L.5
Rozencweig, M.6
Muggia, F.7
-
21
-
-
0017354816
-
Daunomycin-induced cardiotoxicity in children and adults. A review of 110 cases
-
Von Hoff, D. D.; Rozencweig, M.; Layard, M.; Slavik, M.; Muggia, F, M, Daunomycin-induced cardiotoxicity in children and adults. A review of 110 cases. Am. J. Med. 62:200-210; 1977.
-
(1977)
Am. J. Med.
, vol.62
, pp. 200-210
-
-
Von Hoff, D.D.1
Rozencweig, M.2
Layard, M.3
Slavik, M.4
Muggia, F.M.5
-
22
-
-
0023411599
-
The structural basis for anthracycline antibiotic stimulation of oxygen consumption by HL-60 cells and mitochondria
-
Burke, T. G.; Pritos, C. A.; Sartorelli, A. C.; Tritton, T. R. The structural basis for anthracycline antibiotic stimulation of oxygen consumption by HL-60 cells and mitochondria. Cancer Biochem. Biophys. 9:245-255; 1987.
-
(1987)
Cancer Biochem. Biophys.
, vol.9
, pp. 245-255
-
-
Burke, T.G.1
Pritos, C.A.2
Sartorelli, A.C.3
Tritton, T.R.4
-
25
-
-
0026631130
-
Thermodynamics of the anthracycline-nuclei interactions in drug-resistant and drug-sensitive K562 cells
-
Tarasiuk, A.; Garnier-Suillerot, A. Thermodynamics of the anthracycline-nuclei interactions in drug-resistant and drug-sensitive K562 cells. Biochem. Pharmacol. 43:2575-2580; 1992.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2575-2580
-
-
Tarasiuk, A.1
Garnier-Suillerot, A.2
-
26
-
-
0025817761
-
An electron paramagnetic resonance study of the interactions between the adriamycin semiquinone, hydrogen peroxide, iron-chelators, and radical scavengers
-
Kalyanaraman, B.; Morehouse, K. M.; Mason, R. P. An electron paramagnetic resonance study of the interactions between the adriamycin semiquinone, hydrogen peroxide, iron-chelators, and radical scavengers. Arch. Biochem. Biophys. 286:164-171; 1991.
-
(1991)
Arch. Biochem. Biophys.
, vol.286
, pp. 164-171
-
-
Kalyanaraman, B.1
Morehouse, K.M.2
Mason, R.P.3
-
27
-
-
0024444116
-
Free radicals induced by adriamycin-sensitive and adriamycin-resistant cells: A spin trapping study
-
Alegria, A. F.; Samuni, A.; Mitchell, J. B.; Riesz, P.; Russo, A. Free radicals induced by adriamycin-sensitive and adriamycin-resistant cells: A spin trapping study. Biochemistry 28:8653-8658; 1989.
-
(1989)
Biochemistry
, vol.28
, pp. 8653-8658
-
-
Alegria, A.F.1
Samuni, A.2
Mitchell, J.B.3
Riesz, P.4
Russo, A.5
-
28
-
-
0026567982
-
NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumor agents and generation of hydroxyl radicals
-
Fisher, G. R.; Gutierrez, P. L.; Oldcorne, M. A.; Patterson, L. H. NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumor agents and generation of hydroxyl radicals. Biochem. Pharmacol. 43:575-585; 1992.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 575-585
-
-
Fisher, G.R.1
Gutierrez, P.L.2
Oldcorne, M.A.3
Patterson, L.H.4
-
29
-
-
0028217545
-
An HPLC and spectrophotometric study of the hydrolysis of ICRF-187 ((+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane) and its one-ring opened intermediates
-
Hasinoff, B. B. An HPLC and spectrophotometric study of the hydrolysis of ICRF-187 ((+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane) and its one-ring opened intermediates. Int. J. Pharmaceut. 107:67-76; 1994.
-
(1994)
Int. J. Pharmaceut.
, vol.107
, pp. 67-76
-
-
Hasinoff, B.B.1
-
30
-
-
0028093440
-
Pharmacodynamics of the hydrolysis-activation of the cardioprotective agent ICRF-187 ((+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane)
-
Hasinoff, B. B. Pharmacodynamics of the hydrolysis-activation of the cardioprotective agent ICRF-187 ((+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane)). J. Pharm. Sci. 83:64-67; 1994.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 64-67
-
-
Hasinoff, B.B.1
-
31
-
-
0020356720
-
Membrane transport of anthracyclines
-
Skovsgaard, T.; Nissen, N. I. Membrane transport of anthracyclines. Pharmacol. Ther. 18:293-311; 1982.
-
(1982)
Pharmacol. Ther.
, vol.18
, pp. 293-311
-
-
Skovsgaard, T.1
Nissen, N.I.2
-
32
-
-
0006695295
-
Screening of anthracycline analogs
-
Lown, J. W., ed. Amsterdam: Elsevier
-
Grandi, M.; Giuliani, F. C.; Verhoef, V.; Filippi, J. Screening of anthracycline analogs. In: Lown, J. W., ed. Anthracycline and anthracenedione-based anticancer agents. Vol. 6. Amsterdam: Elsevier; 1988:571-597.
-
(1988)
Anthracycline and Anthracenedione-based Anticancer Agents
, vol.6
, pp. 571-597
-
-
Grandi, M.1
Giuliani, F.C.2
Verhoef, V.3
Filippi, J.4
-
33
-
-
0026666922
-
Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug resistant leukemia cells
-
Berman, E.; McBride, M. Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug resistant leukemia cells. Blood 79:3267-3272; 1992.
-
(1992)
Blood
, vol.79
, pp. 3267-3272
-
-
Berman, E.1
McBride, M.2
-
34
-
-
0022967083
-
Redox cycling of anthracyclines by cardiac mitrochondria. I. Anthracycline radical formation by NADH dehydrogenase
-
Davies, K. J. A.; Doroshow, J. H. Redox cycling of anthracyclines by cardiac mitrochondria. I. Anthracycline radical formation by NADH dehydrogenase. J. Biol. Chem. 261:3060-3067; 1986.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 3060-3067
-
-
Davies, K.J.A.1
Doroshow, J.H.2
-
35
-
-
0000547360
-
Biochemical mechanisms of tumor cell kill by the anthracyclines
-
Lown, J. W., ed. Amsterdam: Elsevier
-
Myers. C. E.; Mimnaugh, E. G.; Yeh, G. C.; Sinha, B. K. Biochemical mechanisms of tumor cell kill by the anthracyclines, In: Lown, J. W., ed. Anthracycline and anthracenedione-based anticancer agents. Vol. 6. Amsterdam: Elsevier; 1988:527-569.
-
(1988)
Anthracycline and Anthracenedione-based Anticancer Agents
, vol.6
, pp. 527-569
-
-
Myers, C.E.1
Mimnaugh, E.G.2
Yeh, G.C.3
Sinha, B.K.4
-
36
-
-
0025193951
-
Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity
-
Goormaghtigh, E.; Huart, P.; Praet, M.; Brasseur, R.; Ruysschaert, J.-M. Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity. Biophys. Chem. 35:247-257; 1990.
-
(1990)
Biophys. Chem.
, vol.35
, pp. 247-257
-
-
Goormaghtigh, E.1
Huart, P.2
Praet, M.3
Brasseur, R.4
Ruysschaert, J.-M.5
-
37
-
-
0025285617
-
Transverse location of anthracyclines in lipid bilayers. Paramagnetic quenching studies
-
Constantinides, P. P.; Wang, Y. Y.; Burke, T. G.; Tritton, T. R. Transverse location of anthracyclines in lipid bilayers. Paramagnetic quenching studies. Biophys. Chem. 35:259-264; 1990.
-
(1990)
Biophys. Chem.
, vol.35
, pp. 259-264
-
-
Constantinides, P.P.1
Wang, Y.Y.2
Burke, T.G.3
Tritton, T.R.4
-
38
-
-
0021971399
-
Transplasma-membrane redox systems in growth and development
-
Crane, F. L.; Sun, I. L.; Clark, M. G.; Grebing, C.; Low, H. Transplasma-membrane redox systems in growth and development. Biochim. Biophys. Acta 811:233-264; 1985.
-
(1985)
Biochim. Biophys. Acta
, vol.811
, pp. 233-264
-
-
Crane, F.L.1
Sun, I.L.2
Clark, M.G.3
Grebing, C.4
Low, H.5
-
39
-
-
0025312980
-
Semiquinones derived from anthraquinone-containing antitumor drugs can partition into phosphatidylcholine bilayers
-
Alegria, A. E,; Rodriguez, M. S.; Hernandez, J. Semiquinones derived from anthraquinone-containing antitumor drugs can partition into phosphatidylcholine bilayers. Biochim. Biophys. Acta 1035:51-55; 1990.
-
(1990)
Biochim. Biophys. Acta
, vol.1035
, pp. 51-55
-
-
Alegria, A.E.1
Rodriguez, M.S.2
Hernandez, J.3
-
40
-
-
0025309204
-
In vitro circumvention of anthracycline-resistance in ehrlich ascites tumor by anthracycline analogues
-
Friche, E.; Jensen, P. B.; Roed, H.; Skovsgaard, T.; Nissen, N. I. In vitro circumvention of anthracycline-resistance in ehrlich ascites tumor by anthracycline analogues. Biochem. Pharmacol. 39:1721-1726; 1990.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 1721-1726
-
-
Friche, E.1
Jensen, P.B.2
Roed, H.3
Skovsgaard, T.4
Nissen, N.I.5
-
41
-
-
0026102728
-
Comparison of cytoxicity in heart cells and tumor cells exposed to to DNA intercalating agents in vitro
-
Dorr, R. T.; Shipp, N. G.; Lee, K. M. Comparison of cytoxicity in heart cells and tumor cells exposed to to DNA intercalating agents in vitro. Anti-Cancer Drugs 2:27-33; 1991.
-
(1991)
Anti-cancer Drugs
, vol.2
, pp. 27-33
-
-
Dorr, R.T.1
Shipp, N.G.2
Lee, K.M.3
-
42
-
-
0024412294
-
Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: A comparative study
-
Vile, G. F.; Winterbourn, C. C. Microsomal lipid peroxidation induced by Adriamycin, epirubicin, daunorubicin and mitoxantrone: A comparative study. Cancer Chemother. Pharmacol. 24:105-108; 1989.
-
(1989)
Cancer Chemother. Pharmacol.
, vol.24
, pp. 105-108
-
-
Vile, G.F.1
Winterbourn, C.C.2
-
43
-
-
0024322699
-
A functional assessment of the relative cardiotoxicity of adriamycin and epirubicin in the rat
-
Yeung, T. K.; Simmonds, R. H.; Hopewell, J. W. A functional assessment of the relative cardiotoxicity of adriamycin and epirubicin in the rat. Radiother. Oncol. 15:275-284; 1989.
-
(1989)
Radiother. Oncol.
, vol.15
, pp. 275-284
-
-
Yeung, T.K.1
Simmonds, R.H.2
Hopewell, J.W.3
-
44
-
-
0023684933
-
Different cytoxicity and metabolism of doxorubicin, daunorubicin, epirubicin, esorubicin and idarubicin in cultured human and rat hepatocytes
-
Le Bot, M. A.; Begue, J. M.; Kernaleguen, D.; Robert, J.; Ratanasavanh, D.; Airiau, J.; Riche, C.; Guillouzo, A. Different cytoxicity and metabolism of doxorubicin, daunorubicin, epirubicin, esorubicin and idarubicin in cultured human and rat hepatocytes. Biochem. Pharmacol. 37:3877-3887; 1988.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 3877-3887
-
-
Le Bot, M.A.1
Begue, J.M.2
Kernaleguen, D.3
Robert, J.4
Ratanasavanh, D.5
Airiau, J.6
Riche, C.7
Guillouzo, A.8
-
45
-
-
0026425619
-
Inhibition of topoisomerase II by antitumor agents bis (2,6-dioxopiperazine) derivatives
-
Tanabe, K.; Ikegami, Y.; lshida, R.; Andoh, T. Inhibition of topoisomerase II by antitumor agents bis (2,6-dioxopiperazine) derivatives. Cancer Res. 51:4903-4908; 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 4903-4908
-
-
Tanabe, K.1
Ikegami, Y.2
Lshida, R.3
Andoh, T.4
-
46
-
-
0027486375
-
The enzymatic ring-opening reactions of the chiral cardioprotective agent (+)(S)-ICRF-187 and its (-)(R)-enantiomer ICRF-186 by dihydropyrimidine amidohydrolase
-
Hasinoff, B. B. The enzymatic ring-opening reactions of the chiral cardioprotective agent (+)(S)-ICRF-187 and its (-)(R)-enantiomer ICRF-186 by dihydropyrimidine amidohydrolase. Drug Metab. Dispos. 21:883-888; 1993.
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 883-888
-
-
Hasinoff, B.B.1
-
47
-
-
0026496068
-
Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin
-
Hochster, H.; Liebes, L.; Wadler, S.; Oratz, R.; Wernz, J. C.; Meyers, M.; Green, M.; Blum, R. H.; Speyer, J. L. Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin. J. Natl. Cancer Inst. 84:1725-1730; 1992.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1725-1730
-
-
Hochster, H.1
Liebes, L.2
Wadler, S.3
Oratz, R.4
Wernz, J.C.5
Meyers, M.6
Green, M.7
Blum, R.H.8
Speyer, J.L.9
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