Optimal radiolabeled liposomes for tumor imaging

Journal of Nuclear Medicine

Volumn 37, Issue 2, 1996, Pages 326-332

  Ogihara Umeda, Izumi ^a   Sasaki, Toru ^a   Kojima, Shuji ^a   Nishigori, Hideo ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

gallium 67; indium 111; liposome; technetium 99m; tumor imaging

Indexed keywords

GALLIUM 67; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; INDIUM 111; LIPOSOME; TECHNETIUM 99M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; EARLY DIAGNOSIS; IMAGE ANALYSIS; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TUMOR CELL CULTURE; TUMOR DIAGNOSIS; TUMOR MODEL;

ANIMALS; GALLIUM RADIOISOTOPES; INDIUM RADIOISOTOPES; LIPOSOMES; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; SARCOMA 180; TECHNETIUM; TISSUE DISTRIBUTION;

EID: 0029892331     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Woodle MC, Lasic DD. Sterically stabilized liposomes Biochim Biophys Acta 1992;1113:171-199.
2. Gregoriadis G, Florence AT Liposomes in drug delivery - clinical, diagnostic and ophthalmic potential. Drugs 1993,45:15-28.
3. Cande VJ. Technical and biological considerations on the use of radiolabeled liposomes for diagnostic imaging Nucl Med Biol 1990;17.35-39.
4. 111In-NTA biodistribution in mice J Nucl Med 1983;24.45-51.
5. Proffitt RT, Williams LE, Presant CA, et al. Liposomal blockade of the reticuloendothelial system, improved tumor imaging with small unilamellar vesicles. Science 1983;220 502-504.
6. 67Ga-carrying liposomes Eur J Nucl Med 1986;11.405-411.
7. Ogihara I, Kojima S, Jay M. Differential uptake of gallium-67-labeled liposomes between tumors and inflammatory lesions in rats. J Nucl Med 1986 27 1300-1307.
8. Ogihara-Umeda I, Kojima S. Increased delivery of gallium-67 to tumors using serum-stable liposomes J Nucl Med 1988;29.516-528.
9. Ogihara-Umeda I, Kojima S. Cholesterol enhances the delivery of liposome-encapsulated gallium-67 to tumors. Eur J Nucl Med 1989;15:612-617
10. Ogihara-Umeda I, Sasaki T, Nishigori H Development of a liposome-encapsulated radionuclide with preferential tumor accumulation - the choice of radionuclide and chelating ligand Nucl Med Biol 1992;19:753-757.
11. Ogihara-Umeda I, Sasaki T, Toyama H, Oda K, Senda M, Nishigori H Rapid tumor imaging by active background reduction using biotin-bearing liposomes and avidin. Cancer Res 1994;54.463-467.
12. Presant CA, Proffitt RT, Turner AF, et al Successful imaging of human cancer with indium-111-labeled phospholipid vesicles Cancer 1988,62:905-911
13. Presant CA, Blayney D, Proffitt RT, et al. Preliminary report imaging of Kaposi sarcoma and lymphoma in AIDS with indium-111-labeled liposomes Lancet 1990, 335 1307-1309.
14. Kubo A, Nakamura K, Sammiya T, et al. Indium-111-labeled liposomes dosimetry and tumor detection in patients with cancer. Eur J Nucl Med 1993;20 107-113.
15. Phillips W, Rudolph A, Goins B, Timmons J, Klipper R, Blumhardt R. A simple method for producing technetium-99m-labeled liposome which is stable in vivo Nucl Med Biol 1992;19:539-547
16. Albritton EC Standard values in blood Philadelphia. WB Sanders, 1952.
17. Wu MS, Robbins JC, Bugianesi RL, et al Modified in vivo behavior of liposomes containing synthetic glycolipids. Biochim Biophys Acta 1981;674:19-29
18. Papahadjopoulos D, Allen T, Gabizon A, et al. Sterically stabilized liposomes significant improvements in blood clearance, tissues disposition and therapeutic index of encapsulate drugs against implanted tumors. Proc Natl Acad Sci 1991,88:11460-11464.
19. Woodle MC. Gallium-67-labeled liposomes with prolonged circulation preparation and potential as nuclear imaging agents. Nucl Med Biol 1993;20:149-155