Autoantibodies against arterial antigens characterization by elisa and immunoblot analysis in the spontaneously hypertensive rat

Clinical and Experimental Hypertension

Volumn 18, Issue 1, 1996, Pages 21-35

  Ofosu Appiah, W ^a   Huang, L Y ^a   Kuhnle, M ^a   Sfeir, G ^a   Kennel, A ^a  

^a MASONIC MEDICAL RESEARCH LABORATORY   (United States)

Author keywords

Arterial antigen; Autoantibodies; Autoimmunity; Hypertension

Indexed keywords

ARTERIAL ANTIGEN; AUTOANTIBODY; IMMUNOGLOBULIN G ANTIBODY; UNCLASSIFIED DRUG;

AGE; ANIMAL MODEL; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPERTENSION; IMMUNOBLOTTING; NONHUMAN; PATHOGENESIS; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0029892325     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.3109/10641969609082604     Document Type: Article

References (26)

1. Norman, R.A, Dzielak, D.J, Bost, K.L, Khraibi, AA, Galloway, P G. Immune system dysfunction contributes to the etiology of spontaneous hypertension J Hypertens. 1985, 3 261-268.
2. Fannon, L D, Braylan, RC, Ian Phillips, M Alterations of lymphocyte populations during development in the spontaneously hypertensive rat. J Hypertens 1992; 10. 629-634.
3. Ofosu-Appiah, W , Ruggiero, C Abnormal activation and loss of suppressor T cells in the spontaneously hypertensive rat. Cell Immunol 1992, 145 130-145.
4. Takeichi, N., Suzuki, K., Okayasu, T , Kobayashi, H. Immunological depression in spontaneously hypertensive rats. Clin Exp Immunol. 1980; 40: 120-126.
5. Takeichi, N., Ba, D., Kobayashi, H Natural cytotoxic autoantibody against thymocytes in spontaneously hypertensive rats. Cell Immunol. 1981; 60: 181-190.
6. Dzielak, D.J. Aids, lupus, rheumatoid arthritis-hypertension? Hypertens. 1990; 15: 96-96.
7. Bendich, A., Belisle, E.H, Strausser, H.R. Immune system modulation and its effect on blood pressure of spontaneously hypertensive male and female rat Biochem Biophys Res Commun. 1981, 99: 600-607
8. Ba, D., Takeichi, N., Kodama, T , Kobayashi, H Restoration of T cell depression and suppression of blood pressure in spontaneously hypertensive rats (SHR) by thymus grafts or thymus extracts. J Immunol. 1982; 128: 1211-1216.
9. Khraibi, A.A, Norman, R.A, Dzielak, D.J. Chronic immunosuppression attenuates hypertension in Okamoto spontaneously hypertensive rats. Am J Physiol. (Heart Circ. Physiol) 1984; 247: H722-H726
10. Olsen, F Transfer of arterial hypertension by splenic cells from DOCA-salt hypertensive and renal hypertensive rats to normotensive rats. Acta Pathol Microbiol Scand 1980; 88: 1-5.
11. Budman, D R , Steinberg, A.D. Hypertension and renal disease in SLE Arch Intern Med 1976, 136 1003-1007
12. Martinez-Amenos, A., Buendia, E., Carreras, L , Font, I., Mestre, M , Rama, H., Sarrias, X., Alsina, J. Humoral and cellular immunologica, abnormalities in hypertensive patients J Clin Hypertens. 1985, 2: 153-160
13. Savige, J.A, Gallicchio, M., Georgiou, T., Davies, D.J Diverse target antigens recognized by circulating antibodies in anti-neutrophil cytoplasm antibody-associated renal vasculitides Clin Exp Immunol 1990, 82 238-243.
14. Khraibi, A. A, Smith, T.L, Hutchins, P M, Lynch, C D, Dusseau, J.W Thymectomy delays the development of hypertension in Okamoto spontaneously hypertensive rats.J Hypertens. 1987, 5. 537-541
15. Chen, C-M., Schacter, D Elevation of plasma immunoglobulin A in the spontaneously hypertensive rat Hypertension 1993, 21. 731-738.
16. Takeichi, N , Hamada, J-I, Takimoto, M., Fujiwara, K , Kobayashi, H Depression of T cell-mediated immunity and enhancement of autoantibody production by natural infection with microorganisms in spontaneously hypertensive rats (SHR). Microbiol Immunol. 1988; 32: 1235-1244.
17. Kristensen, B O., Andersen, P L Increased serum levels of immunoglobulins in untreated and treated essential hypertension. I: Relation to to blood pressure. Acta Med. Scand. 1978; 203: 55-59.
18. Mikkelsen, W.M., Dodge, H.J , Duff, J.F., Kato, H.J. Estimates of the prevalence of rheumatic diseases in the population of Tecumseh Michigan, 1959-60 J Chronic Dis. 1967; 20:351-369.
19. Feitkamp, T E., Mees, D.E.J , Nieuwenhius, M.B. Autoantibodies related to treatment with chlorthalidone and alpha-methyldopa. Acta Med Scand. 1970; 187: 219-223.
20. Olsen, F. Delayed hypersensitivity and essential hypertension Acta Path Microbiol Scand B. 1974; 82: 448-450.
21. Gudbrandsson, T., Hansson, L., Herlitz, H., Lindholm, L., Nilson, L.A. Immunological changes in patients with previous malignant essential hypertension Lancet 1981; I: 406-408.
22. Hardin, J.A., Rahn, D.R., Shen, C., Lerner, M.R., Wolin, S.L., Rosa, M.D., Steitz, J.A. Antibodies from patients with connective tissue diseases bind specific subsets of cellular RNA-protein particles. J Clin Invest. 1982; 70: 141-147.
23. Jacob, H.J., Lindpainter, K., Lincoln, S.E., Kusumi, K., Bunker, R.K., et al. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. Cell 1991, 67: 213-224
24. Stuart, J.M., Dixon, F J Serum transfer of collagen-induced arthritis in mice. J Exp Med. 1983, 158: 378-392.
25. Gomez, C.M., Richman, D.P. Chronic experimental autoimmune myasthenia gravis induced by monoclonal antibofy to acetylcholine receptor: biochemical and electrophysiological criteria J immunol. 1987, 139 73-76
26. Holt, C M., Lindsey, N , Moult, J , Malia, R.G., et al. Antibody-dependent cellular cytotoxicity of vascular endothelium characterization and pathogenic associations in systemic sclerosis Clin Exp Immunol 1989; 78: 359-365.