Continuous production of L-tert-leucine in series of two enzyme membrane reactors: Modelling and computer simulation

Bioprocess and Biosystems Engineering

Volumn 14, Issue 6, 1996, Pages 291-297

  Kragl, U ^a   Vasic Racki, D ^b   Wandrey, C ^a  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; CHEMICAL REACTION KINETICS; COMPUTER SIMULATION; CONTROLLED STUDY; ENZYME KINETICS; MODEL; NONHUMAN; PRIORITY JOURNAL;

EID: 0029891893     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Kragl, U.; Vasic-Racki, Dj.; Wandrey, C.: Continuous processes with soluble enzymes. Chem. Ing. Tech. 64 (1992) 499-509. Indian J. Chem. Sect. B 32 (1993) 103-117
2. Kragl, U.; Vasic-Racki, Dj.; Wandrey, C.: Continuous processes with soluble enzymes. Chem. Ing. Tech. 64 (1992) 499-509. Indian J. Chem. Sect. B 32 (1993) 103-117
3. Bommarius, A.S.; Drauz, K.; Groeger, U.; Wandrey, C.: Membrane bioreactors for the production of enantiomerically pure α-amino acids. In: Collins, A.N.; Sheldrake, C.N.; and Crosby, J. (Eds): Chirality in industry, pp. 372-395. London: J. Wiley 1992
4. Wandrey, C.; Bossow, B.: Continuous cofactor regeneration - utilisation of polymer bound NAD (H) for the production of optically active acids. Biotechnol. Bioind. 3 (1986) 8-13
5. Ohshima, T.; Soda, K.: Thermostable amino acid dehydrogenases: applications and gene cloning. Trends Biotechnol. 7 (1989) 210-214
6. Bommarius, A.S.; Schwarm, M.; Stingl, K.; Kottenhahn, M.; Huthmacher, K.; Drauz, K. Synhesis and use of enantiomerically pure tert-leucine. Tetrahedron: Asymmetry 6 (1995) 2851-2888
7. Weuster-Botz, D.; Paschold, H.; Striegel, B.; Gieren, H.; Kula, M.-R.; Wandrey, C.: Continuous computer controlled production of formate dehydrogenase and isolation on a pilot scale. Chem. Eng. Technol. 17 (1994) 131-137
8. 15N-L-glutamic acid. Tetrahedron: Asymmetry 4 (1993) 1193-1202
9. Kragl, U.; Kruse, W.; Hummel, W.; Wandrey, C.: Enzyme engineering aspects of biocatalysis: cofactor regeneration as example. Biotechnol. Bioeng. (Accepted for publication)
10. Deuflhard, P.: A modified Newton method for the solution of ill-conditioned systems of nonlinear equations with application to multiple shooting. Numer. Math. 22 (1974) 289