Is the minimal model too minimal?

Diabetologia

Volumn 39, Issue 8, 1996, Pages 997-1000

  Caumo, A ^a   Vicini, P ^b   Cobelli, C ^b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

GLUCOSE BLOOD LEVEL; HUMAN; INSULIN SENSITIVITY; KINETICS; MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0029891448     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00403922     Document Type: Short Survey

References (10)

1. Bergman RN, Ider YZ, Bowden CR, Cobelli C (1979) Quantitative estimation of insulin sensitivity. Am J Physiol 236: E667-E677
2. Bergman RN, Phillips NLS, Cobelli C (1981) Physiologic evaluation of factors controlling glucose tolerance in man. Measurement of insulin sensitivity and beta-cell sensitivity from the response to intravenous glucose. J Clin Invest 68: 1456-1467
3. Cobelli C. Pacini G, Toffolo G, Sacca L (1986) Estimation of insulin sensitivity and glucose clearance from minimal model: new insights from labeled IVGTT. Am J Physiol 250: E591-E598
4. Caumo A, Giacca A, Morgesc M, Pozza G, Micossi P, Cobelli C (1991) Minimal model of glucose disappearance: lessons from the labelled IVGTT. Diabet Med 8: 822-832
5. Caumo A, Cobelli C (1993) Hepatic glucose production during the labeled IVGTT: estimation by deconvolution with a new minimal model. Am J Physiol 264: E829-E841
6. Quon MJ, Cochran C, Taylor SI. Eastman RC (1994) Non-insulin mediated glucose disappearance in subjects with IDDM: discordance between experimental results and minimal model analysis. Diabetes 43: 890-896
7. Saad MF, Anderson RL, Laws A et al. for the IRAS (1994) A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Diabetes 43: 1114-1121
8. Radziuk J, Norwich KH, Vranic M (1978) Experimental validation of measurements of glucose turnover in non-steady state. Am J Physiol 234: E84-E93
9. Cobelli C, Toffolo G, Ferrannini F, (1984) A model of glucose kinetics and their control by insulin, compartmental and noncompartmental approaches. Math Biosci 72: 291-315
10. Cobelli C, Mari A, Ferrannini E (1987) Non-steady-state: error analysis of Steele's model and developments for glucose kinetics. Am J Physiol 252: E679-E689