Synthesis and antitumor activity of novel distamycin derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 11, 1996, Pages 1241-1246

  Baraldi, Pier Giovanni ^a   Beria, Italo ^b   Cacciari, Barbara ^a   Cozzi, Paolo ^b   Franzetti, Cristina ^b   Mongelli, Nicola ^b   Romagnoli, Romeo ^a   Spalluto, Giampiero ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISTAMYCIN A DERIVATIVE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; MOUSE; MURINE LEUKEMIA; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALIA; MURINAE;

EID: 0029891345     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00204-1     Document Type: Article

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17. 6-DMSO) δ 11.05 (1H, s), 10.51 (1H, s), 10.03 (1H, s), 9.95 (1H, s), 8.99 (2H,s), 8.63 (1H,s), 8.25 (1H, bs), 7.36 (1H, s), 7.32 (1H, s), 7.25 (1H, s), 7.2 (1H, s), 7.1 (1H, s), 7.07 (1H, s), 6.6 (1H, d, J = 1.7 Hz), 6.32 (1H, d, J = 1.7 Hz), 4.05 (3H, s), 3.87 (3H, s), 3.84 (3H, s), 3.81 (3H, s), 3.48 (2H, t, J = 6 Hz), 2.58 (2H, t, J = 6 Hz).
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