Transcripts from a novel human KRAB zinc finger gene contain spliced Alu and endogenous retroviral segments

Genomics

Volumn 33, Issue 3, 1996, Pages 463-472

  Baban, Soheyl ^a   Freeman, J Douglas ^a   Mager, Dixie L ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; ZINC FINGER PROTEIN;

ALU SEQUENCE; ARTICLE; DNA SEQUENCE; DNA STRUCTURE; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; RNA SPLICING;

HUMAN ENDOGENOUS RETROVIRUS; HUMAN ENDOGENOUS RETROVIRUS H; UNIDENTIFIED RETROVIRUS;

EID: 0029891320     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0221     Document Type: Article

References (41)

1. Abrink, M., Aveskogh, M., and Hellman, L. (1995). Isolation of cDNA clones for 42 different Krüppel related zinc finger proteins expressed in the human monoblast cell line U-937. DNA Cell Biol. 14: 125-136.
2. Banville, D., and Boie, Y. (1989). Retroviral long terminal repeat is the promoter of the gene encoding the tumor-associated calcium-binding protein oncomodulin in the rat. J. Mol. Biol. 207: 481-490.
3. Bellefroid, E. J., Lecocq, P. J., Benhida, A., Poncelet, D. A., Belayew, A., and Martial, J. A. (1989). The human genome contains hundreds of genes coding for finger proteins of the Krüppel type. DNA 8: 377-387.
4. Bellefroid, E. J., Marine, J.-C., Ried, T., Lecocq, P. J., Rivière, M., Amemiya, C., Poncelet, D. A., Coulie, P. G., de Jong, P., Szpirer, C., Ward, D. C., and Martial, J. A. (1993). Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. EMBO J. 12: 1363-1374.
5. Bellefroid, E. J., Poncelet, D. A., Lecocq, P. J., Revelant, O., and Martial, J. A. (1991). The evolutionary conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins. Proc. Natl. Acad. Sci. USA 88: 3608-3612.
6. Berg, D. E., and Howe, M. M. (Eds.) (1989). "Mobile DNA." Am. Soc. Microbiol., Washington, DC.
7. Brini, A. T., Lee, G. M., and Kinet, J.-P. (1993). Involvement of Alu sequences in the cell-specific regulation of transcription of the γ chain of Fc and T cell receptors. J. Biol. Chem. 268: 1355-1361.
8. Chang-Yeh, A., Mold, D. E., and Huang, R. C. C. (1991). Identification of a novel murine IAP-promoted placenta-expressed gene. Nucleic Acids Res. 19: 3667-3672.
9. Chowdhury, K., Rohdewohld, H., and Gruss, P. (1988). Specific and ubiquitous expression of different zinc finger protein genes in the mouse. Nucleic Acids Res. 16: 9995-10011.
10. Devereux, J., Haeberli, P., and Smithies, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12: 387-395.
11. Di Cristofano, A., Strazzullo, M., Longo, L., and LaMantia, G. (1995). Characterization and genomic mapping of the ZNF80 locus: Expression of this zinc-finger gene is driven by a solitary LTR of ERV9 endogenous retroviral family. Nucleic Acids Res. 23: 2823-2830.
12. El Baradi, T. E., and Pieler, T. (1991). Zinc finger proteins: What we know and what we would like to know. Mech. Dev. 35: 155-169.
13. Favor, J., and Morawetz, C. (1992). Insertional mutations in mammals and mammalian cells. Mutat. Res. 284: 53-74.
14. Feuchter, A. E., Freeman, J. D., and Mager, D. L. (1992). Strategy for detecting cellular transcripts promoted by human endogenous long terminal repeats: Identification of a novel gene (CDC4L) with homology to yeast CDC4. Genomics 13: 1237-1246.
15. Feuchter-Murthy, A. E., Freeman, J. D., and Mager, D. L. (1993). Splicing of a human endogenous retrovirus to a novel phospholipase A2 related gene. Nucleic Acids Res. 21: 135-143.
16. Goodchild, N. L., Wilkinson, D. A., and Mager, D. L. (1992). A human endogenous retrovirus provides a polyadenylation signal to a novel, alternatively spliced transcript in normal placenta. Gene 121:287-294.
17. Hambor, J. E., Mennone, J., Coon, M. E., Hanke, J. H., and Kavathas, P. (1993). Identification and characterization of an Alu-containing, T-cell-specific enhancer located in the last intron of the human CD8α gene. Mol. Cell. Biol. 13: 7056-7070.
18. Hirose, Y., Takamatsu, M., and Harada, F. (1993). Presence of env genes in members of the RTVL-H family of human endogenous retrovirus-like elements. Virology 192: 52-61.
19. Johansen, T., Holm, T., and Bjørklid, E. (1989). Members of the RTVL-H family of human endogenous retrovirus-like elements are expressed in placenta. Gene 79: 259-267.
20. Jurka, J., and Smith, T. (1988). A fundamental division in the Alu family of repeated sequences. Proc. Natl. Acad. Sci. USA 85:4775-4778.
21. Kato, N., Shimotohno, K., Van Leeuwen, D., and Cohen, M. (1990). Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Krüppel. Mol. Cell. Biol. 10: 4401-4405.
22. Kozak, M. (1991). Structural features in eukaryotic mRNAs that modulate the initiation of translation. J. Biol. Chem. 266: 19867-19870.
23. Labuda, D., Zietkiewicz, E., and Mitchell, G. A. (1995). Alu elements as a source of genomic variation: Deleterious effects and evolutionary novelties. In "The Impact of Short Interspersed Elements (SINEs) on the Host Genome" (R. Maraia, Ed.), pp. 1-24, R. G. Landes Austin, TX.
24. Mager, D., and Goodchild, N. (1989). Homologous recombination between the LTRs of a human retrovirus-like element causes a 5-kb deletion in two siblings. Am. J. Hum. Genet. 45: 848-854.
25. Mager, D. L., and Freeman, J. D. (1995). HERV-H endogenous retro viruses: Presence in the New World branch but amplification in the Old World primate lineage. Virology 213: 395-404.
26. Mager, D. L., and Henthorn, P. S. (1984). Identification of a retrovirus-like repetitive element in human DNA. Proc. Natl. Acad. Sci. USA 81: 7510-7514.
27. Makalowski, W., Mitchell, G. A., and Labuda, D. (1994). Alu sequences in the coding regions of mRNA: A source of protein variability. Trends Genet. 10: 188-193.
28. Margolin, J. F., Friedman, J. R., Meyer, W. K.-H., Vissing, H., Thiesen, H-J., and Rauscher F. J. III, (1994). Krüppel-associated boxes are potent transcriptional repression domains. Proc. Natl. Acad. Sci. USA 91: 4509-4513.
29. Rosati, M., Marino, M., Franze, A., Tramontane, A., and Grimaldi, G. (1991). Members of the zinc finger protein gene family sharing a conserved N-terminal module. Nucleic Acids Res. 19: 5661-5667.
30. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). "Molecular Cloning: A Laboratory Manual," 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
31. Shapiro, M. B., and Senapathy, P. (1987). RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15: 7155-7174.
32. Skowronski, J., Fanning, T. G., and Singer, M. (1988). Unit-length Line-1 transcripts in human teratocarcinoma cells. Mol. Cell. Biol. 8: 1385-1397.
33. Tabor, S., and Richardson, C. C. (1987). DNA sequence analysis with a modified bacteriophage T7 polymerase. Proc. Natl. Acad. Sci. USA 84: 4767-4771.
34. Thiesen, H. J. (1990). Multiple genes encoding zinc finger domains are expressed in human T cells. New Biol. 2: 363-374.
35. Ting, C.-N., Rosenberg, M. P., Snow, C. M., Samuelson, L. C., and Meisler, M. H. (1992). Endogenous retroviral sequences are required for tissue-specific expression of a human salivary amylase gene. Genes Dev. 6: 1457-1465.
36. Wilkinson, D. A., and Mager, D. L. (1993). RTVL-H human endogenous retrovirus-like elements with an intact pol and an env-related region. J. Cancer Res. Clin. Oncol. 199 (Suppl. 1):S8.
37. Wilkinson, D. A., Freeman, J. D., Goodchild, N. L., Kelleher, C. A., and Mager, D. L. (1990). Autonomous expression of RTVL-H endogenous retroviruslike elements in human cells. J. Virol. 64: 2157-2167.
38. Wilkinson, D. A., Goodchild, N. L., Saxton, T. M., Wood, S., and Mager, D. L. (1993). Evidence for a functional subclass of the RTVL-H family of human endogenous retrovirus-like sequences. J. Virol. 67: 2981-2989.
39. Wilkinson, D. A., Mager, D. L., and Leong, J. C. (1994). Endogenous human retroviruses. In "The Retroviridae" (J. Levy, Ed.), Vol. 3, pp. 465-535, Plenum, New York.
40. Witzgall, R., O'Leary, E., Leaf, A., Onaldi, D., and Bonventre, J. V. (1994). The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. Proc. Natl. Acad. Sci. USA 91: 4514-4518.
41. Yulug, I. G., Yulug, A., and Fisher, E. M. C. (1995). The frequency and position of Alu repeats in cDNAs, as determined by database searching. Genomics 27: 544-548.