Target cell-induced apoptosis of interleukin-2-activated human natural killer cells: Roles of cell surface molecules and intracellular events

Blood

Volumn 87, Issue 12, 1996, Pages 5127-5135

  Yamauchi, Akira ^a   Taga, Kazuyuki ^a   Mostowski, Howard S ^a   Bloom, Eda T ^a,b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD11B ANTIGEN; CD16 ANTIGEN; CD18 ANTIGEN; CD2 ANTIGEN; DNA FRAGMENT; HERBIMYCIN A; INTERLEUKIN 2; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY; PROTEINASE; PROTEINASE INHIBITOR; RNA; TYROSINE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIAGNOSIS; DNA DEGRADATION; HUMAN; HUMAN CELL; LYMPHOKINE ACTIVATED KILLER CELL; MEMBRANE DAMAGE; NATURAL KILLER CELL; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TARGET CELL;

EID: 0029891315     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.12.5127.bloodjournal87125127     Document Type: Article

References (53)

1. + T lymphocytes. J Immunol 151:2368, 1993
2. Ullberg M, Jondal M: Recycling and target binding capacity of human natural killer cells. J Exp Med 153:615, 1981
3. Windebank KP, Abraham RT, Powis G, Olsen RA, Barna TJ, Leibson PJ: Signal transduction during human natural killer cell activation: Inositol phosphate generation and regulation by cyclic AMP. J Immunol 141:3951, 1988
4. Melero I, Salmeron S, Balboa MA, Aramburu J, López-Botet M: Tyrosine kinase-dependent activation of human NK cell functions upon stimulation through a 58-kDa surface antigen selectively expressed on discrete subsets of NK cells and T lymphocytes. J Immunol 152:1662, 1994
5. Arroyo AG, Campanero MR, Sánchez-Mateos P, Zapata JM, Ursa A, del Pozo MA, Sánchez-Madrid F: Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by CD45 tyrosine phosphatase. J Cell Biol 126:1277, 1994
6. Sugie K, Minami Y, Kawakami T, Uchida A: Stimulation of NK-like YT cells via leukocyte function-associated antigen (LFA)-1. Possible involvement of LFA-1-associated tyrosine kinase in signal transduction after recognition of NK target cells. J Immunol 154:1691, 1995
7. Umehara H, Takashima A, Minami Y, Bloom ET: Signal transduction via phosphorylated adhesion molecule, LFA-1β (CD18), is increased by culture of natural (NK) cells with interleukin (IL)-2 in the generation of lymphokine activated killer (LAK) cells. Int Immunol 5:19, 1993
8. Taga K, Yamauchi A, Bloom ET, Tosato G: Target-induced death by apoptosis in human lymphokine-activated natural killer cells. Blood 87:2411, 1996
9. Crispe IN: Fatal interactions: Fas-induced apoptosis of mature T cells. Immunity 1:347, 1994
10. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F, Lynch DH: Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 181:71, 1995
11. Williams MS, Henkart PA: Apoptotic cell death induced by intracellular proteolysis. J Immunol 153:4247, 1994
12. + donors by cysteine protease inhibitors. J Immunol 153:862, 1994
13. Sarin A, Adams DH, Henkart PA: Protease inhibitors selectively block T cell receptor-triggered programmed cell death in a murine T cell hybridoma and activated peripheral T cells. J Exp Med 178:1693, 1993
14. Su B, Bochan MR, Hanna WL, Froelich CJ, Brahmi Z: Human granzyme B is essential for DNA fragmentation of susceptible target cells. Eur J Immunol 24:2073, 1994
15. Alderson MR, Tough TW, Braddy S, Davis-Smith T, Roux E, Schooley K, Miller RE, Lynch DH: Regulation of apoptosis and T cell activation by Fas-specific mAb. Int Immunol 6:1799, 1994
16. Piechaczyk M, Blanchard JM, Marty L, Dani Ch, Panabieres F, Sabouty SE, Fort Ph, Jeanteur Ph: Post-transcriptional regulation of glyceraldehyde-3-dehydrogenase gene expression in rat tissues. Nucleic Acids Res 12:6951, 1984
17. Yamauchi A, Bloom ET: Requirement of thiol compounds as reducing agents for IL-2-mediated induction of LAK activity and proliferation of human NK cells. J Immunol 151:5535, 1993
18. Ramsdell FJ, Shau H, Golub SH: Role of proliferation in LAK cell development. Cancer Immunol Immunother 26:139, 1988
19. 51Cr-release assay for CTL-mediated target cell lysis, in Sitkovsky MV, Henkart PA (eds): Cytotoxic Cells. Recognition, Effector Function, Generation, and Methods. Boston, MA, Birkhäuser, 1993, p 457
20. Zychlinsky A, Zheng LM, Liu C-C, Young JD-E: Cytolytic lymphocytes induced both apoptosis and necrosis in target cells. J Immunol 146:393, 1991
21. Matzinger P: The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 145:185, 1991
22. Wright SC, Zhong J, Larrick JW: Inhibition of apoptosis as a mechanism of tumor promotion. FASEB J 8:654, 1994
23. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680, 1970
24. Takebe Y, Seiki M, Fujisawa J-I, Hoy P, Yokota K, Arai K-I, Yoshida M, Arai N: SRα promoter: An efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol Cell Biol 8:466, 1988
25. Teshigawara K, Katsura Y: A simple and efficient mammalian gene expression system using an EBV-based vector transfected by electroporation in G2/M phase. Nucleic Acids Res 20:2607, 1992
26. DeBlaker-Hohe DF, Yamauchi A, Yu C-R, Horvath-Arcidiacono JA, Bloom ET: IL-12 synergizes with IL-2 to induce lymphokine activated cytotoxicity and perform and granzyme gene expression in fresh human NK cells. Cell Immunol 165:33, 1995
27. Umehara H, Minami Y, Domae N, Bloom ET: Increased processing of lymphocyte function associated-antigen-1 in human natural killer cells stimulated with interleukin-2. Int Immunol 6:1071, 1994
28. Savary CA, Lotzová E: Adhesion molecules on MHC-nonrestricted lymphocytes: High density expression and role in oncolysis. Lymphokine Cytokine Res 11:149, 1992
29. Takahashi T, Ishikura H, Iwai K, Takahashi C, Kato H, Tanabe T, Yoshiki T: Cytokine regulation of cell-to-cell interactions in lymphokine-activated killer cell cytotoxicity in vitro. Cancer Immunol Immunother 36:76, 1993
30. Azuma A, Yagita H, Matsuda H, Okumura K, Niitani H: Induction of intercellular adhesion molecule 1 on small cell lung carcinoma cell lines by γ-interferon enhances spontaneous and bispecific anti-CD3 X antitumor antibody-directed lymphokine-activated killer cell cytotoxicity. Cancer Res 52:4890, 1992
31. Nagata S: Fas and Fas ligand: A death factor and its receptor. Adv Immunol 57:129, 1994
32. Ortaldo JR, Mason AT, O'Shea JJ: Receptor induced death in human NK cells: Involvement of CD16. J Exp Med 181:339, 1995
33. Azzoni L, Anegon I, Calabretta B, Perussia B: Ligand binding to FcγR induces c-myc-dependent apoptosis in IL-2-stimulated NK cells. J Immunol 154:491, 1995
34. Azuma M, Cayabyab M, Buck D, Phillips JH, Lanier LL: Involvement of CD28 in MHC-unrestricted cytotoxicity mediated by a human natural killer leukemia cell line. J Immunol 149:1115, 1992
35. Azuma M, Yssel H, Phillips JH, Spits H: Functional expression of B7/BB1 on activated T lymphocytes. J Exp Med 177:845, 1993
36. Yen K-Y, Pulaski BA, Woods ML, McAdam AJ, Gaspari AA, Frelinger JG, Lord EM: B7-1 enhances natural killer cell-mediated cytotoxicity and inhibits tumor growth of a poorly immunogenic murine carcinoma. Cell Immunol 165:217, 1995
37. Cleveland JL, Ihle JN: Contenders in FasL/TNF death signaling. Cell 81:479, 1995
38. Ashwell JD, Berger NA, Cidlowski JA, Lane DP, Korsmeyer SJ: Coming to terms with death: Apoptosis in cancer and immune development. Immunol Today 15:147, 1994
39. Squier MKT, Sehnert AJ, Cohen JJ: Apoptosis in leukocytes. J Leukoc Biol 57:2, 1995
40. Surh CD, Sprent J: T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100, 1994
41. Nagata S, Golstein P: The Fas death factor. Science 267:1449, 1995
42. Robertson MJ, Caligiuri MA, Manley TJ, Levine H, Ritz J: Human natural killer cell adhesion molecules. Differential expression after activation and participation in cytolysis. J Immunol 145:3194, 1990
43. Patarroyo M, Prieto J, Rincon J, Timonen T, Lundberg C, Lindbom L, Åsjö B, Gahmberg CG: Leukocyte-cell adhesion: A molecular process fundamental in leukocyte physiology. Immunol Rev 114:67, 1990
44. Mäenpää A, Jääskeläinen J, Carpén O, Patarroyo M, Timonen T: Expression of integrins and other adhesion molecules on NK cells; impact of IL-2 on short- and long-term cultures. Int J Cancer 53:850, 1993
45. Melero I, Balboa MA, Alonso JL, Yagüe E, Pivel JP, Sanchez-Madrid F, López-Botet M: Signaling through the LFA-1 leucocyte integrin actively regulates intercellular adhesion and tumor necrosis factor-α production in natural killer cells. Eur J Immunol 23:1859, 1993
46. Vyth-Dreese FA, Dellemijn TAM, Frijhoff A, van Kooyk Y, Figdor CG: Role of LFA-1/ICAM-1 in interleukin-2-stimulated lymphocyte proliferation. Eur J Immunol 23:3292, 1993
47. Chong SS-F, Boussy IA, Jiang X, Lamas M, Graf LH Jr: CD54/ICAM-1 is a costimulator of NK cell-mediated cytotoxicity. Cell Immunol 157:92, 1994
48. Sugie K, Nakamura K, Teshigawara K, Diamond MS, Springer TA, Nakamura Y, Leonard WJ, Uchida A, Yodoi J: Activation of natural killer cells by the mAb TA-1 that recognizes leukocyte function-associated antigen-1. Int Immunol 7:763, 1995
49. 1 integrins. Blood 85:1858, 1995
50. Shi L, Kam C-M, Powers JC, Aebersold R, Greenberg AH: Purification of three cytotoxic lymphocyte granule serine proteases that induced apoptosis through distinct substrate and target cell interactions. J Exp Med 176:1521, 1992
51. Nakajima H, Henkart PA: Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown. J Immunol 152:1057, 1994
52. Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ: Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76:977, 1994
53. Voelkel-Johnson C, Entingh AJ, Wold WSM, Gooding LR, Laster SM: Activation of intracellular proteases is an early event in TNF-induced apoptosis. J Immunol 154:1707, 1995