Characterisation of the Aspergillus nidulans frA1 mutant: Hexose phosphorylation and apparent lack of involvement of hexokinase in glucose repression

FEMS Microbiology Letters

Volumn 139, Issue 2-3, 1996, Pages 223-228

  Ruijter, George J G ^a   Panneman, Henk ^a   Van Den Broeck, Hetty C ^a   Bennett, James M ^a   Visser, Jaap ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Aspergillus nidulans; complementation; glucokinase; glucose repression; hexokinase; trehalose 6 phosphate

Indexed keywords

GLUCOKINASE; GLUCOSE; HEXOKINASE; HEXOSE;

ARTICLE; ASPERGILLUS NIDULANS; BACTERIUM IDENTIFICATION; BACTERIUM MUTANT; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC COMPLEMENTATION; GLUCOSE METABOLISM; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL;

EID: 0029890944     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(96)00145-0     Document Type: Article

References (25)

1. Lobo, Z. and Maitra, P.K. (1977) Physiology of hexose phosphorylating enzymes in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 182, 639-645.
2. Prior, C., Mamessier, P., Fukuhara, H., Chen, X.J. and Wesolowski-Louvel, M. (1993) The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis. Mol. Cell. Biol. 13, 3882-3889.
3. Rose, M. (1995) Molecular and biochemical characterization of the hexokinase from the starch-utilizing yeast Schwanniomyces occidentalis. Curr. Genet. 27, 330-338.
4. Wedlock, D.N. and Thornton, R.J. (1989) Glucose-negative mutants of Pachysolen tannophilus. J. Gen. Microbiol. 135, 2019-2026.
5. Davidson, E.A. (1960) Hexokinase from Aspergillus parasiticus. J. Biol. Chem. 235, 23-25.
6. Ruiz-Amil, M. and Sols, A. (1961) Hexokinase aus Aspergillus oryzae. Biochem. Z. 334, 168-174
7. Steinböck, F., Choojun, S., Held, I., Röhr, M. and Kubicek, C.P. (1994) Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger. Biochim. Biophys. Acta 1200, 215-223.
8. Lagos, R. and Ureta, T. (1980) The hexokinases from wild-type and morphological mutant strains of Neurospora crassa. Eur. J. Biochem. 104, 357-365
9. Gancedo, J.M. (1992) Carbon catabolite repression in yeast. Eur. J. Biochem. 206, 297-313.
10. Dowzer, C.E.A. and Kelly, J.M. (1991) Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans. Mol. Cell. Biol. 11, 5701-5709.
11. Bailey, C. and Arst Jr., H.N. (1975) Carbon catabolite repression in Aspergillus nidulans. Eur. J. Biochem. 51, 573-77.
12. Van der Veen, P., Arst Jr., H.N., Flipphi, M.J.A. and Visser, J. (1994) Extracellular arabinases in Aspergillus nidulans: The effect of different cre mutations on enzyme levels. Arch. Microbiol. 162, 433-440.
13. Pontecorvo, G., Roper, J.A., Hemmons, L.J., Macdonald, K.J. and Bufton, A.W.J. (1953) The genetics of Aspergillus nidulans. Adv. Genet. 5, 141-238.
14. Vishniac, W. and Santer, M. (1957) The Thiobacilli. Bacteriol. Rev. 21, 195-213.
15. Witteveen, C.F.B., Busink, R., Van de Vondervoort, P.J.I., Dijkema, C., Swart, K. and Visser, J. (1989) L-Arabinose and D-xylose catabolism in Aspergillus niger. J. Gen. Microbiol. 135, 2163-2171.
16. Greaser, E.H., Porter, R.L., Britt, K.A., Pateman, J.A. and Doy, C.H. (1985) Purification and preliminary characterization of alcohol dehydrogenase from Aspergillus nidulans. Biochem. J. 225, 449-454.
17. Creaser, E.H., Porter, R.L. and Pateman, J.A. (1987) Purification and properties of aldehyde dehydrogenase from Aspergillus nidulans. Int. J. Biochem. 19, 1009-1012.
18. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular cloning: a laboratory manual, 2nd edition, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
19. De Graaff L., Van den Broeck, H.C. and Visser, J. (1988) Isolation and transformation of the pyruvate kinase gene of Aspergillus nidulans. Curr. Genet. 13, 315-321.
20. Kusters van Someren, M.A., Harmsen, J.A.M., Kester, H.C.M. and Visser J. (1991) Structure of the Aspergillus niger pelA gene and its expression in Aspergillus niger and Aspergillus nidulans. Curr. Genet. 20, 293-299.
21. Roberts, C.F. (1963) The genetic analysis of carbohydrate utilization in Aspergillus nidulans. J. Gen. Microbiol. 31, 45-58.
22. Blázquez, M.A., Lagunas, R., Gancedo, C. and Gancedo, J.M. (1993) Trehalose-6-phosphate, a new regulator of yeast glycolysis that inhibits hexokinases. FEBS Lett. 329, 51-54.
23. Malardier, L., Daboussi, M.J., Julien, J., Roussel, F., Scazzocchio, C. and Brygoo, Y. (1989) Cloning of the nitrate reductase gene (niaD) of Aspergillus nidulans and its use for transformation of Fusarium oxysporum. Gene 78, 147-156.
24. Gems, D.H. and Clutterbuck, A.J. (1993) Co-transformation with autonomously-replicating helper plasmids facilitates gene cloning from an Aspergillus nidulans gene library. Curr. Genet. 24, 520-524
25. Arst Jr., H.N., Tollervey, D., Dowzer, C.E.A. and Kelly, J.M. (1990) An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression. Mol. Microbiol. 4, 851-854.